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What is the main use of 1H-Pyrrolo [2,3-c] pyridine, 7-chloro-4-Methoxy-?
7-Chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to assist in the synthesis of many biologically active compounds. Due to its unique chemical structure, it can interact with specific targets in organisms or participate in the drug development process, laying the foundation for the creation of new therapeutic drugs.
In the field of organic synthesis, it is also an important building block. With the chemical activity of chlorine atoms and methoxy groups, other functional groups can be introduced through various organic reactions, such as nucleophilic substitution, coupling reactions, etc., and then more complex and diverse organic molecules can be built, which is of great significance for expanding the structural types of organic compounds.
In addition, in the field of materials science, rational design and modification may endow materials with specific properties, such as affecting the photoelectric properties of materials, which has great potential in the development of new functional materials. It is expected to bring new breakthroughs and development opportunities in this field.
What are the physical properties of 1H-Pyrrolo [2,3-c] pyridine, 7-chloro-4-Methoxy-
7-Chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine, this is an organic compound. Its physical properties are related to many aspects, let me tell you one by one.
Looking at its appearance, under room temperature and pressure, it is mostly in a solid state, but the exact color state may vary depending on the purity and crystal form. It is usually white to light yellow powder, just like the color of the first snow in winter or the afterglow of autumn, delicate and pure.
When it comes to the melting point, it has been determined by many experiments that it is about a certain temperature range, which is the critical range for the compound to change from solid to liquid. At this temperature, the force between molecules changes, and the lattice structure gradually disintegrates, just like ice melts in the warm sun. The determination of the melting point is of great significance for identifying the purity and characteristics of this compound. If the purity is high, the melting point range is narrow and approaches the theoretical value; if it contains impurities, the melting point is reduced and the range is wider.
In terms of boiling point, due to the complexity of the compound structure, it can boil at normal pressure or at a higher temperature and transform into a gaseous state. The value of the boiling point is also affected by the pressure of the surrounding environment. When the pressure decreases, the boiling point also decreases.
Solubility is also an important physical property. In organic solvents, such as common ethanol, dichloromethane, etc., or show a certain solubility. In ethanol, or due to the formation of hydrogen bonds between molecules and other interactions, part of the solution is dissolved, and the clarity of the solution may vary depending on the concentration. In water, due to its structure containing hydrophobic parts, the solubility is poor, just like oil drops in water, it is difficult to blend. This property is also related to its molecular polarity. The polarity is weak, so it is not well soluble with water with strong polarity.
Density is also the key to consider. Although the exact value needs to be determined by precise experiments, it can be inferred that its density is different from that of common organic solvents or water. This density characteristic affects the sedimentation and delamination of substances during separation, purification and related chemical processes, and is related to the effectiveness of practical operations.
In summary, the physical properties of 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine are diverse, and each property is interrelated to determine its state and behavior in different environments. It is of great value in the scientific research and industrial application fields.
What is the synthesis method of 1H-Pyrrolo [2,3-c] pyridine, 7-chloro-4-Methoxy-
To prepare 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine, the following method can be followed.
First take a suitable starting material, such as a pyridine or pyrrole derivative with a suitable substituent. This starting material needs to contain a group that can be converted into the desired target structure through a specific reaction.
Taking the nucleophilic substitution reaction as an example, if the starting material contains a group that can be replaced by a chlorine atom, a suitable chlorination reagent, such as thionyl chloride or phosphorus oxychloride, can be selected. Under suitable reaction conditions, such as in a suitable solvent, control the temperature and reaction time to allow the chlorination reagent to fully react with the raw material to introduce chlorine atoms at the specified position.
As for the introduction of methoxy groups, nucleophilic substitution reactions can be used. Select reagents containing methoxy groups, such as sodium methoxide or a combination of iodomethane and sodium alcohol. In a suitable reaction system, active hydrogen or halogen atoms in the raw materials can react with methoxy reagents, so that methoxy groups can be integrated into the target molecule.
During the reaction process, the choice of solvent is crucial. The choice of reactants and reaction types, such as polar aprotic solvents such as dimethylformamide (DMF) or dichloromethane, is required to facilitate the smooth progress of the reaction. Temperature must also be precisely controlled. Different reaction steps require different temperatures, either low temperature to facilitate the protection of specific groups, or high temperature to promote the rapid completion of the reaction.
After the reaction is completed, the separation and purification of the product is indispensable. Column chromatography can be used to separate the product and the impurity according to the difference in the partition coefficient between the stationary phase and the mobile phase. Recrystallization can also be used to select an appropriate solvent, and the solubility of the product and the impurity at different temperatures can be used to obtain a pure product.
Thus, through carefully designed reaction steps, precise control of reaction conditions, and meticulous separation and purification, 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine can be obtained.
In which fields is 1H-Pyrrolo [2,3-c] pyridine, 7-chloro-4-Methoxy- used?
7-Chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine is very useful in the field of pharmaceutical research and development. Due to its unique chemical structure, it can be used as a key component of active compounds for the creation of new drugs, such as anti-tumor, antiviral and neurological diseases. In the development of anti-tumor drugs, it may be able to precisely act on specific targets of cancer cells by virtue of its structural characteristics, inhibiting the growth and spread of cancer cells, and contributing to the solution of cancer problems.
In the field of materials science, it also shows potential value. Or it can be chemically modified to make it have unique optical and electrical properties, and then applied to the preparation of new materials such as organic Light Emitting Diode (OLED) and organic solar cells. It helps OLED to improve luminous efficiency and stability, optimize the photoelectric conversion efficiency of organic solar cells, and promote the progress of materials science.
Furthermore, it also has applications in the creation of pesticides. After rational design and modification, it may become a new type of pesticide active ingredient with high efficiency, low toxicity and environmental friendliness, which can effectively control crop diseases and pests, ensure agricultural harvest, and is of great significance for sustainable agricultural development. In conclusion, 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine has broad application prospects in many fields such as medicine, materials and pesticides, and is worthy of further exploration and research.
What is the market outlook for 1H-Pyrrolo [2,3-c] pyridine, 7-chloro-4-Methoxy-?
7-Chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine, this substance is worth exploring in today's world.
Looking at its past, there is no detailed record to be found, but in the current fields of medicine and chemical industry, it is gradually emerging. In the medical field, many scholars have dedicated themselves to studying, hoping to use its unique molecular structure to develop new specific drugs. Due to the particularity of its structure, it may be able to show a unique affinity for specific disease targets, bringing hope for the conquest of intractable diseases.
In the chemical industry, there are also many skilled craftsmen pondering its application in material synthesis. Or through ingenious processes, it can be integrated into new materials to give the material unique physical and chemical properties, such as enhanced stability and changed optical properties.
Although its potential is remarkable, there are still many thorns ahead. The complexity of the synthesis process and the high cost remain, which is an urgent barrier to be overcome. Only chemical experts can carefully study and improve the optimization process to reduce costs and increase output. Furthermore, safety and environmental impact considerations cannot be ignored. Rigorous tests are required to ensure that it is harmless to humans and animals and the environment in production applications.
Over time, if many difficulties can be overcome, 7-chloro-4-methoxy-1H-pyrrolido [2,3-c] pyridine will surely shine in the market, adding a strong touch to the pharmaceutical and chemical industries, benefiting the common people, and promoting the vigorous progress of the industry.
