1H-Pyrrolo[2,3-b]pyridine-5-ol

The chemical structure of 1H-pyrrolido [2,3-b] pyridine-5-ol is quite subtle. This compound contains the structure of pyrrole and pyridine phase, which is like the fusion of two rings, forming a unique shape.
Looking at its structure, the pyrrole ring and the pyridine ring are fused in a specific way. In the structure of pyrrolido [2,3-b] pyridine, the 1H label indicates the presence of a hydrogen atom in the first position of the pyrrole ring. The location of this hydrogen atom has a significant impact on the chemical properties and reactivity of the compound.
In addition, 5-alcohol is added to the fifth position of the parallel ring structure. The introduction of hydroxyl groups, like a stroke of genius, endows the compound with many characteristics. Hydroxyl groups are hydrophilic, which makes the compound more soluble in polar solvents; and hydroxyl groups, as active groups, can participate in various chemical reactions, such as esterification, etherification, etc., and then derive many derivatives, which are of great value in the fields of organic synthesis and drug development.
The chemical structure of 1H-pyrrolido [2,3-b] pyridine-5-ol, the fusion of pyrrole and pyridine, and its unique hydroxyl group are worthy of further investigation in the field of organic chemistry.

1H-pyrrolido [2,3-b] pyridine-5-ol is an organic compound, and its common physical properties are as follows:
Viewed, most of them are solid at room temperature, but they may vary slightly due to differences in purity and crystallization conditions. Its color is often white to light yellow powder, with a pure and delicate appearance. This compound has different solubility in different solvents. In water, the solubility is quite limited, and the molecular structure polarity matches the polarity of water poorly. However, in polar organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), the solubility is relatively high, and it can dissolve well to form a uniform solution. This property is used in chemical synthesis and drug development to facilitate the selection of suitable reaction solvents and promote the reaction.
Its melting point is also an important physical property. After determination, the melting point is in a specific temperature range, which can be used as a key basis for identifying the purity and structure of the compound. The higher the purity, the closer the melting point is to the theoretical value, and the narrower the melting range. In the field of chemical analysis and quality control, melting point determination is often an effective means to detect the purity of compounds.
In addition, 1H-pyrrolido [2,3-b] pyridine-5-ol has certain stability and can be stored for a long time without significant decomposition or deterioration under conventional conditions. However, when exposed to extreme chemical environments such as strong oxidizing agents, strong acids, and strong bases, its structure may be damaged, triggering chemical reactions and generating new compounds.
In summary, the physical properties of 1H-pyrrolido [2,3-b] pyridine-5-ol, such as appearance, solubility, melting point, and stability, are of great significance for understanding its chemical behavior and application in various fields. It provides a key reference for chemists in the synthesis, analysis, and application of this compound.

1H-pyrrolido [2,3-b] pyridine-5-ol is an organic compound. It has a wide range of uses and is a key drug synthesis intermediate in the field of medicine. The development and production of many drugs for the treatment of neurological diseases, cardiovascular diseases and tumors require the use of this compound to construct a specific molecular structure to achieve the desired pharmacological activity and therapeutic efficacy.
In the field of materials science, 1H-pyrrolido [2,3-b] pyridine-5-ol also has applications. It can be chemically modified and polymerized to prepare organic materials with special photoelectric properties for use in organic Light Emitting Diodes (OLEDs), solar cells and other devices. Due to its unique molecular structure and electronic properties, it can effectively improve the charge transport efficiency and luminous efficiency of materials, thereby optimizing device performance.
In addition, in the field of organic synthetic chemistry, this compound is often used as an important starting material and reaction intermediate. With its activity check point, it can carry out many types of chemical reactions, such as nucleophilic substitution, oxidation reduction, cyclization, etc., to help synthesize complex organic molecules and provide important support for the development of organic synthetic chemistry. In conclusion, 1H-pyrrolido [2,3-b] pyridine-5-ol has shown important application value in many fields such as medicine, materials science and organic synthesis, and plays an indispensable role in promoting scientific research and technological development in related fields.

The synthesis method of 1H-pyrrolido [2,3-b] pyridine-5-ol is quite complicated. In the past, the method may have started with specific pyridine derivatives and gradually constructed pyrrole rings with delicate reaction steps. If a suitable substitute for pyridine is taken first, under specific conditions, it meets a reagent containing an active group, and after a condensation reaction, the prototype of pyrrolido-pyridine is initially established.
At that time, the reaction temperature and pH may need to be carefully regulated. If the temperature is too high, side reactions may occur; if the acid-base imbalance, the reaction process will be blocked. To obtain the preliminary product, it needs to be purified several times, such as column chromatography, to remove impurities and obtain a pure intermediate.
Then, the specific position of the intermediate is hydroxylated. This step also requires precise control of the conditions, selection of appropriate hydroxylating reagents, and control of the reaction time. The activity and dosage of the reagents used are all about success or failure.
There are other methods, based on the construction strategy of heterocycles, starting from other heterocycles, through multi-step transformation, pyridine and pyrrole fragments are introduced, and finally the ring is formed into 1H-pyrrolido [2,3-b] pyridine-5-ol. In the meantime, metal catalysis may be involved, and the unique activity of metal catalysts can be used to promote the formation and fracture of bonds.
However, the choice and dosage of metal catalysts need to be carefully considered. Using too much is expensive and difficult to deal with; using too little, the reaction rate is slow. And after each step of the reaction, fine testing is required to confirm that the structure and purity of the product are correct before proceeding to the next step. The road of synthesis is step by step, with a slight mistake, and it is all lost. The synthesizer needs to be skilled and meticulous in order to obtain this target product.

I look at you and ask "What is the price range of 1H - Pyrrolo [2,3 - b] pyridine - 5 - ol in the market". However, the price of this product in the market often varies for many reasons, and it is difficult to know with certainty.
First, the purity of this product is extremely critical. If the purity is high and there are few impurities, it is suitable for high-end scientific research or special industrial uses, and the price is high. On the contrary, if the purity is slightly lower, the price may be slightly lower.
Second, the supply and demand also affect the price. If the market demand for this product is strong and the supply is scarce, the price will rise; if the supply is sufficient and the demand is flat, the price may stabilize or decrease. < Br >
Third, the difficulty and cost of preparation also affect its price. If the preparation process is complicated and special raw materials and equipment are required, the cost is high and the price is also high.
There are also factors such as sales channels and regional differences. Generally speaking, in the scientific research reagent market, small batches and high purity can cost hundreds or even thousands of yuan per gram. If it is purchased in industrial batches, the unit price may be slightly reduced due to large quantities, but it also depends on the specific situation.
Therefore, in order to determine the exact price range of "1H - Pyrrolo [2,3 - b] pyridine - 5 - ol", it is necessary to carefully consider the above factors and consult the relevant suppliers or market practitioners to obtain a more accurate price.