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What is the main use of 1H-Pyrrolo [2,3-b] pyridine, 4-methoxy- (9CI)
1H-pyrrolido [2,3-b] pyridine-4-methoxy (9CI), this is an organic compound. It has a wide range of uses in the field of medicinal chemistry, and is mostly used as a key intermediate to help synthesize various biologically active compounds. In the process of many drug research and development, it acts as a starting material or an important module. After chemical modification and reaction, it can create new drug molecules with diverse structures, which are of great significance for the treatment of diseases.
In the field of materials science, it may be used to prepare functional materials. With its unique molecular structure, it endows materials with special electrical and optical properties. For example, when preparing organic Light Emitting Diode (OLED) materials, its structure can affect the luminous efficiency and color purity, contributing to the development of new display technologies.
In the field of organic synthetic chemistry, as a characteristic structural unit, it can participate in the construction of many complex organic molecules. With the help of various chemical reactions, it is connected with other organic fragments to construct novel structures, expand the structural diversity of organic compounds, and inject vitality into the development of organic synthetic chemistry.
However, the specific use of this compound varies according to different research and application scenarios. In practical application, chemists will design and react it according to the needs of the target product to give full play to its potential value in various fields.
What are the physical properties of 1H-Pyrrolo [2,3-b] pyridine, 4-methoxy- (9CI)
1H-pyrrolido [2,3-b] pyridine, 4-methoxyl- (9CI), this is an organic compound. Its physical properties are quite important for its application in various scenarios.
Let's talk about the appearance first. Under normal circumstances, this substance may appear as a white to light yellow solid powder. This color and morphology are common characteristics of many organic compounds, determined by their molecular structure and crystallization habits. Its powder shape is convenient for weighing and subsequent experimental operations, and also indicates that its crystal structure is relatively loose.
Besides the melting point, after many experimental measurements and theoretical calculations, its melting point is about a certain temperature range. Melting point is an intrinsic property of a substance and depends on intermolecular forces. In this compound, molecules are maintained by interactions such as hydrogen bonds and van der Waals forces. When the external temperature reaches the melting point, the molecule obtains enough energy to break free from these forces, thus transforming from a solid state to a liquid state. Knowing the melting point is of great significance for the purification and identification of the substance. If the measured melting point is similar to the literature, it can be preliminarily determined that its purity is high.
On the topic of solubility, it has a certain solubility in organic solvents, such as common ethanol and dichloromethane. This is due to the principle of similarity miscibility, and its molecular structure has some polar groups, which can interact with organic solvent molecules. However, the solubility in water is not good. Due to the strong polarity of water molecules, the matching degree of intermolecular forces with this compound is low. This solubility characteristic has a profound impact on its application in organic synthesis reactions. Organic solvents are often used as reaction mediums to ensure full contact with the reactants and promote the smooth progress of the reaction.
In addition, the density of the compound is also one of the physical properties. Although the specific value needs to be determined accurately experimentally, the density range can be inferred based on similar compounds. Density is closely related to the molecular weight of a substance and the degree of molecular accumulation, which affects its behavior in solution and its state when mixed with other substances.
In summary, the physical properties of 1H-pyrrolido [2,3-b] pyridine, 4-methoxyl- (9CI), such as appearance, melting point, solubility, density, etc., reflect their molecular properties from different aspects, laying the foundation for in-depth study of their chemical properties and practical applications.
What is the chemical synthesis method of 1H-Pyrrolo [2,3-b] pyridine, 4-methoxy- (9CI)
To prepare 4-methoxy-1H-pyrrolido [2,3-b] pyridine (9CI), the following ancient method can be used.
Take the appropriate pyridine derivative as the starting material. This material needs to contain modifiable groups to facilitate the subsequent introduction of pyrrole rings and methoxy groups. In a suitable reaction vessel, the pyridine derivative is mixed with a specific reagent, which should be able to promote the connection of the pyrrole ring to the pyrrole ring. The reaction conditions are quite critical and should be controlled within a specific temperature and pressure range. Usually, heat to a moderate temperature to allow the reactants to fully react, or it needs to be protected by an inert gas to prevent side reactions from occurring.
When the pyridine ring is preliminarily connected to the pyrrole ring, a methoxy group is introduced. Select a suitable methoxylation reagent and slowly add it to the reaction system. This process also requires attention to factors such as temperature and reaction time to ensure that the methoxy group is accurately replaced at the target position. After the methoxy group is successfully introduced, the reaction product or impurities must be separated and purified. Common methods such as column chromatography and recrystallization can be used to obtain pure 4-methoxy-1H-pyrrolido [2,3-b] pyridine. < Br >
When operating, be sure to follow the specifications of each step carefully, pay attention to the amount of reagents and changes in reaction conditions, so as to improve the yield and purity of the product.
What is the price range of 1H-Pyrrolo [2,3-b] pyridine, 4-methoxy- (9CI) in the market?
I don't know the price range of 1H - Pyrrolo [2,3 - b] pyridine, 4 - methoxy - (9CI) in the market. However, if you want to know its price, you can follow various ways. First, check in detail on various chemical trading platforms. Such platforms often gather many suppliers with different prices, or the approximate price range can be obtained. Second, contact the chemical supplier directly to inquire about the price of the product. The price quoted by the supplier may be different due to different costs and quantities. Third, consult relevant industry reports, research literature, or find past price information for reference. However, due to the constant changes in the market, raw material prices, supply and demand conditions, and other factors can cause their prices to fluctuate. Therefore, in order to obtain accurate prices, real-time inquiries are essential.
What are the safety and risks of 1H-Pyrrolo [2,3-b] pyridine, 4-methoxy- (9CI)?
1H-pyrrolido [2,3-b] pyridine-4-methoxy (9CI), this is an organic compound. In terms of its safety and risk, it needs to be carefully investigated from multiple ends.
Looking at its chemical structure, it contains the combination of nitrogen heterocycle and methoxy group, or causes it to have specific chemical activities. From a toxicity point of view, due to the lack of detailed experimental data, it is difficult to accurately determine the degree of toxicity to organisms. However, many compounds containing similar nitrogen heterocycle structures may have certain toxicity, or can invade the human body through inhalation, skin contact, ingestion, etc., damage liver, kidney and other organs, or even interfere with nervous system function.
In terms of environmental risks, its behavioral characteristics in the environment are unknown. However, if it enters the natural environment, or due to chemical stability and bioaccumulation, it will cause long-term effects on the ecosystem. For example, it may affect the survival and reproduction of aquatic organisms, or pass through the food chain, endangering higher organisms.
In terms of use and storage, due to its chemical properties or relatively active, it should be placed in a cool, dry and well-ventilated place, away from fire sources and oxidants, to prevent severe chemical reactions, causing serious accidents such as fires or explosions.
In summary, although the safety and risk awareness of 1H-pyrrolido [2,3-b] pyridine-4-methoxy (9CI) is still limited, due to its structural characteristics and experience with similar compounds, appropriate protective and management measures must be taken during use, storage and handling to reduce its potential harm to humans and the environment.