1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid, 5-bromo-

1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid, 5-bromine, its chemical properties are quite complex. The structure of pyridine and pyrrole in this compound gives it a unique electron cloud distribution and reactivity.
In terms of acidity, the carboxyl group at the 3-position can ionize hydrogen ions, which is acidic and can neutralize with bases to form corresponding carboxylic salts. In organic synthesis, this carboxyl group can participate in esterification reactions and form ester compounds with alcohols catalyzed by acids. This reaction is an important means of building carbon-oxygen bonds. The bromine atom at the
5-position has high reactivity and can undergo nucleophilic substitution reactions. When encountering nucleophilic reagents, bromine atoms are easily replaced, thus introducing other functional groups to expand the structure and function of the compound. For example, by reacting with nucleophilic reagents containing nitrogen, oxygen, sulfur, etc., new carbon-heteroatom bonds can be formed, which greatly enriches the types and properties of compounds.
In addition, the conjugate system of the compound makes it have certain optical properties, or can absorb light of specific wavelengths, which may have potential applications in the field of photochemistry. At the same time, the rigidity and planarity of its structure affect the interaction between molecules, which has an important impact on its crystal structure and aggregation behavior in solution, and then relates to its physical and chemical properties. The many chemical properties of this compound make it show broad application prospects in many fields such as medicinal chemistry and materials science.

1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid, 5-bromine, has a wide range of uses. It is often used as a key intermediate in the field of medicine. For example, the development of anti-tumor drugs can use its unique chemical structure, through a series of reactions, combined with specific targets, to interfere with tumor cell growth and proliferation signaling pathways, in order to achieve therapeutic effect. In the field of pesticides, agents with high insecticidal and bactericidal properties can be developed. With its structural characteristics, it can act on the physiological processes of pests and pathogens, inhibit their reproduction and invasion, and protect crop growth. In materials science, it also has potential uses. Materials that can be chemically modified to produce special optoelectronic properties, such as organic Light Emitting Diode (OLED) materials, are expected to improve the display performance of OLEDs because of their structure, which can affect electron transmission and luminous efficiency, and play an important role in the development of display technology.
The use of this compound, with the deepening of scientific research and technological refinement, or more expansion and innovation, plays a more critical role in various fields, bringing positive impact on human life and technological progress.

The synthesis of 1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid and 5-bromine is a key issue in organic synthetic chemistry. To prepare this substance, the following ancient methods can be followed.
First, pyridine derivatives are used as starting materials, and bromine atoms are introduced through halogenation. For this halogenation reaction, it is often necessary to select suitable halogenating reagents, such as bromine ($Br_2 $) or N-bromosuccinimide (NBS), and the reaction temperature and time need to be controlled so that the bromine atoms fall precisely in the fifth position of the pyridine ring. This step of reaction is like craftsmen carving jade, and it is necessary to accurately grasp the scale to obtain the ideal intermediate. < Br >
After the bromine-containing intermediate is obtained, the pyrrole ring is constructed. This goal is often achieved by condensation reaction. Nitrogen-containing and carbonyl-containing compounds are selected. Under the catalysis of bases, the pyrrole [2,3-b] pyridine skeleton is gradually formed through multi-step complex reactions. The type and dosage of bases, and the characteristics of the reaction solvent all have a profound impact on the reaction process and product purity.
During the synthesis process, each step of the reaction needs to be carefully monitored. The progress of the reaction can be tracked by thin-layer chromatography (TLC), and the raw material consumption and product generation can be judged according to the change of spots. Purification of the product is also crucial. Column chromatography or recrystallization is often used to remove impurities to obtain pure 1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid and 5-bromine.
Although the steps in this synthesis are complicated, every step is like a march, interlocking. Synthesizers need deep chemical skills and exquisite experimental skills to successfully prepare the target product, laying a solid foundation for subsequent organic synthesis research and drug development.

I have not heard of the price of "1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid, 5-bromine" in the market. However, if you want to know the price of this product in the market, you should follow various paths.
First, you can explore the pharmaceutical market. In the pharmaceutical market, all kinds of medicinal materials are sold, or there may be this "1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid, 5-bromine". In the pharmaceutical market, ask the shopkeeper or store, and he may know the price. However, the price of the product in the pharmaceutical market may vary depending on the quality, quantity, time and place. If the quality is good and the quantity is wide, the price may be high; if there is a shortage of goods at the time, and the source is near the place, the price is also different.
Second, you can visit the ancient books of various pharmaceutical shops. In the past, the price of medicinal materials was often remembered in pharmaceutical shops. Although the situation has changed in today's times, it may be possible to observe the signs of its changes. The ancient books contain the price of the past, so as to deduce today's price.
Third, you can ask the industry about this. In the pharmaceutical industry and the process of drug research, there must be those who know "1H-pyrrole [2,3-b] pyridine-3-carboxylic acid, 5-bromine". They often deal with this thing, or know the price of its market, and may be able to say the reason for its price, such as the difficulty of making it, the amount needed.
It is a pity that I have not personally touched the city, and I have not known its exact price in detail. If you want to know, you should follow these several paths, explore it yourself, and observe it carefully, so that you can get the truth of its market price.

1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid, 5-bromine, does have many wonderful uses in the field of medicine.
It shows its talents in the road of anti-tumor. This compound can precisely target specific molecular pathways in tumor cells, and effectively inhibit the proliferation, migration and invasion of tumor cells by inhibiting the activity of key proteins. For example, targeting some cancer cells with specific gene mutations can block abnormally activated signaling pathways and inhibit the growth of cancer cells, just like setting up obstacles on the enemy's march, making it difficult to continue their offensive.
It is also indispensable in the field of drug development for neurological diseases. Due to its unique chemical structure, it can interact with neurotransmitter receptors to regulate nerve signaling. For example, in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, it can adjust the balance of neurotransmitters and improve the function of nerve cells. It is like re-sorting the disordered nervous system and restoring its normal operation.
In the field of anti-infection, there are also extraordinary performances. It can play an antibacterial and antiviral role by interfering with the metabolic process of pathogens or destroying their cellular structure. For some drug-resistant strains, its unique mechanism of action may break through the limitations of traditional drugs and open up new paths for anti-infection treatment, just like adding new weapons to the fight against stubborn bacteria.
It also has potential in the development of drugs for the prevention and treatment of cardiovascular diseases. It can regulate the physiological functions of the cardiovascular system, such as affecting the activity of angiotensin-converting enzymes, regulating blood pressure, and maintaining the stability of the cardiovascular system environment, which seems to build a strong line of defense for cardiovascular health.
From this perspective, 1H-pyrrolido [2,3-b] pyridine-3-carboxylic acid, 5-bromine, is like a shining star in the field of medicine, showing great application potential in the prevention and treatment of many diseases, providing a strong boost for the improvement of human health and well-being.