1H-pyrrolo[2,3-b]pyridine, 2-methyl-

2-Methyl-1H-pyrrolido [2,3-b] pyridine, this is an organic compound. Its chemical properties are unique and have many wonders.
First of all, from the structural point of view, it contains the skeleton of pyrrolido-pyridine, and there are methyl groups connected at the 2 position. This unique structure endows it with specific electronic effects and spatial resistance. The presence of methyl groups can affect the electron cloud distribution of molecules, which in turn affects their chemical activity.
In terms of physical properties, the melting point, boiling point, solubility and other properties of the compound are closely related to the intermolecular forces. Due to the presence of nitrogen atoms in the molecule, intermolecular forces such as hydrogen bonds can be formed, which affects its melting point and boiling point. And its polarity is specific due to its structure, so the solubility in different solvents also varies.
In terms of chemical activity, there are lone pair electrons on the nitrogen atom, which make it alkaline and can react with acids to generate corresponding salts. At the same time, the pyrrole ring is conjugated with the pyridine ring, which makes the molecule have a certain aromaticity and is relatively stable. However, under appropriate conditions, electrophilic substitution reactions can also occur. Because the electron cloud density of the pyridine ring is lower than that of the pyrrole ring, electrophilic substitution reactions are more likely to occur on the pyrrole ring. In addition, the α-hydrogen of the 2-position methyl group has a certain activity, and under conditions such as strong bases, deprotonation can occur, which can lead to a series of reactions, such as substitution reactions with halogenated hydrocarbons, etc., through which molecules can be further modified and derived.
This compound has rich and diverse chemical properties and can be used as an important intermediate in the field of organic synthesis to construct more complex organic molecular structures, laying the foundation for the creation of new drugs and new materials.

2-Methyl-1H-pyrrolido [2,3-b] pyridine is an organic compound that has important uses in many fields.
In the field of medicinal chemistry, it is often used as a key intermediate. In the process of pharmaceutical development, the construction of many drug molecules needs to be based on this nitrogen-containing heterocyclic structure. Due to its unique chemical structure and electronic properties, it can interact with specific targets in organisms. Therefore, in drug design, chemists can use it to construct compounds with specific biological activities to develop new therapeutic drugs, such as specific drugs for certain diseases.
In the field of materials science, this compound also has extraordinary performance. Because of its photoelectric properties, it can be applied to the creation of organic optoelectronic materials. For example, in the research and development of organic Light Emitting Diode (OLED) materials, through ingenious modification and adjustment of their structure, key performance indicators such as material luminous efficiency and stability can be improved, helping to improve the image quality and service life of OLED displays.
In the field of organic synthesis chemistry, 2-methyl-1H-pyrrolido [2,3-b] pyridine, with its special structure, provides an effective starting material or reaction intermediate for the synthesis of more complex organic molecules. Chemists can use various organic synthesis methods to introduce different functional groups according to their structural characteristics, so as to construct a rich and diverse library of organic compounds, which lays the foundation for subsequent scientific research and application development.
In summary, 2-methyl-1H-pyrrolido [2,3-b] pyridine plays an indispensable role in the fields of medicine, materials and organic synthesis, and is of great significance to promote the development of these fields.

The synthesis method of 1H-pyrrolido [2,3-b] pyridine-2-methyl derivatives shall be described in detail.
First, the corresponding pyridine derivatives can be initiated. Take the pyridine derivative first, add a specific nucleophilic reagent in a suitable reaction vessel, and use a strong base as a catalyst to carry out a nucleophilic substitution reaction at a specific temperature, such as between an ice bath and room temperature. In this reaction, the nucleophilic reagent will attack a specific position on the pyridine ring to form a key intermediate. For example, with a methyl-containing nucleophilic reagent, the methyl group is precisely introduced at a specific check point of the pyridine ring through clever design of the reaction conditions, which lays the foundation for the subsequent construction of the pyrrole ring.
Second, the method of constructing pyrrole rings. When a pyridine intermediate containing a specific substituent is obtained, a condensation reaction strategy can be adopted. Adding a suitable condensation agent, such as some reagents with dehydration condensation ability, under heating conditions, prompts the pyridine ring to condensate with another nitrogen-containing compound. This process is like a tenon-mortise connection, where the nitrogen-containing compound interacts with a specific part of the pyridine ring, and through cyclization, gradually builds a pyrrole [2,3-b] pyridine structural framework. During this period, the reaction temperature and time need to be strictly controlled to prevent side reactions from occurring.
Third, optimize the modification. After the basic skeleton is synthesized, the product can be modified. If 2-methyl needs to be further modified, a halogenation reaction can be used. In a specific reaction system, a halogenating agent is added to selectively halogenate 2-methyl, and then other functional groups are introduced through a nucleophilic substitution reaction to obtain 1H-pyrrolido [2,3-b] pyridine-2-methyl derivatives with different properties and uses.
The method of synthesizing this compound requires fine regulation of the reaction conditions, clever selection of reagents, and step by step according to the laws of chemistry to obtain the ideal product.

I don't know the price range of 1H - pyrrolo [2,3 - b] pyridine, 2 - methyl - in the market. This is a chemical professional product, and its price often changes due to quality, purity, source, supply and demand. And the market is also complex and changeable, with times changing, and prices are also different. Or you can ask the price at the place where chemical raw materials are traded, or at the chemical reagent supplier. To know the price, you can get a more accurate price when you visit the merchant in person, ask people in the industry, or check the information of the chemical product trading platform. You can't just rely on empty ideas, you must rely on facts to know the approximate price.

Today there is a question, what is the manufacturer of 1H - pyrrolo [2,3 - b] pyridine, 2 - methyl -? This is a question related to a substance in the field of organic chemistry.
In the current chemical industry world, many manufacturers are involved in the production of this substance. There is a well-known Sigma - Aldrich company abroad, which is a giant in the field of chemical reagents. Its products are widely used in scientific research, production and many other aspects. It has a long-standing reputation in the global chemical market. Its production of 1H - pyrrolo [2,3 - b] pyridine, 2 - methyl - is of high quality and is supplied to many scientific research institutions and enterprises.
There are also domestic manufacturers involved. Such as Bailingwei Technology Co., Ltd., the company has been focusing on the supply of chemical reagents and related products for many years. Its products are quite influential in the domestic market. It also produces 1H-pyrrolo [2,3-b] pyridine, 2-methyl -, which can meet the needs of many domestic customers. Another Tixi Ai (Shanghai) Chemical Industry Development Co., Ltd., as a well-known chemical product supplier, has a rich product line, which also includes this substance, which is recognized in the industry for its stable quality.
However, it needs to be clear that the production of this substance by various manufacturers may vary in terms of purity, price, output, etc. Purchasers should choose carefully based on their actual needs, such as the high purity requirements of scientific research experiments or the consideration of cost and output in industrial production.