1H-Pyrrolo[2,3-b]pyridine-2-carboxylicacid,4-bromo-,ethylester

The chemical structure of 1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid, 4-bromo-, ethyl ester is as follows:
The main structure of this compound is pyrrolido [2,3-b] pyridine, which is formed by fusing a pyrrole ring with a pyridine ring. The pyrrole ring and the pyridine ring are connected by specific atoms, and the fusing of the two gives the structure unique stability and reactivity.
In the second position of the pyridine ring, there is a monocarboxylic acid ethyl ester group attached. This ethyl ester group is formed by the esterification reaction of carboxyl group and ethanol, and has the structure of - COOCH 2O CH, in which the presence of carbonyl C = O has a great influence on the physical and chemical properties of the compound, such as affecting its polarity, participating in chemical reactions, and so on.
And at the 4th position of the pyridine ring, a bromine atom is connected. Bromine atoms bring special properties to the whole compound due to their electronegativity and atomic radius characteristics. It can affect the intermolecular forces, such as van der Waals force, which in turn affects the physical properties such as the melting boiling point of the compound; at the same time, in chemical reactions, bromine atoms can participate in many reactions such as nucleophilic substitution as a leaving group, which greatly enriches the chemical transformation path of the compound. In this way, the groups interact and cooperate to form the unique chemical structure and properties of 1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid, 4-bromo-ethyl ester.

4-Bromo-1H-pyrrolido [2,3-b] pyridine-2-carboxylate ethyl ester has a wide range of uses. In the field of medicinal chemistry, it is a key intermediate and can be used to create a variety of new drugs. For example, in the synthesis of some heterocyclic compounds with specific biological activities, it is often used as a starting material and is converted into drug molecules with therapeutic effects through multiple delicate reactions, providing new possibilities for overcoming diseases.
In the field of organic synthetic chemistry, due to its unique structure, it can participate in many reactions, such as coupling reactions, which can be cleverly connected with other organic fragments to build complex and novel organic molecular structures, expand the types and properties of organic compounds, and lay a material foundation for related fields such as materials science.
In terms of pesticide research and development, based on it, it is expected to develop high-efficiency, low-toxicity and environmentally friendly pesticide products. By modifying and optimizing its structure, active ingredients for specific pests or diseases can be precisely designed, the targeting and control effect of pesticides can be improved, and the sustainable development of agriculture can be promoted to ensure the yield and quality of crops.

There are several methods for the synthesis of 1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid, 4-bromo-ethyl ester. One method can also be prepared from the starting material through a multi-step reaction. First take the compound containing the pyridine structure, use an appropriate brominating agent, such as liquid bromine or N-bromosuccinimide (NBS), and under suitable reaction conditions, such as in an inert solvent, add an initiator, heat or light, so that a specific position on the pyridine ring is brominated, and a bromine atom is introduced to obtain a 4-bromo pyridine intermediate.
Then, this intermediate is combined with a compound containing pyrrole structure, in the presence of a condensation agent such as dicyclohexyl carbodiimide (DCC) and a catalyst 4-dimethylaminopyridine (DMAP), in a suitable organic solvent, heated and stirred, and through a condensation reaction, the structure of pyrrole [2,3-b] pyridine is constructed.
Then, carboxylic acid and ethanol are heated under the action of a catalyst such as concentrated sulfuric acid to carry out an esterification reaction to convert the carboxyl group into an ethyl ester group, thereby obtaining the target product 1H-pyrrole [2,3-b] pyridine-2-carboxylic acid, 4-bromo-, ethyl ester.
There is another method, which can first construct the structure of pyrrolido [2,3-b] pyridine, and then introduce bromine atoms at specific positions in the pyridine ring, and finally carry out esterification reaction. The starting material is a compound containing pyrrole and pyridine fragments, and the cyclization reaction forms the pyrrolido [2,3-b] pyridine parent nucleus. Then bromine atoms are introduced with halogenated reagents, and finally the target product is obtained through the esterification step. This synthesis path requires precise control of the reaction conditions at each step. Factors such as the proportion of raw materials, reaction temperature, and time all have a significant impact on the yield and purity of the product. Satisfactory results can only be obtained through careful operation.

4-Bromo-1H-pyrrolido [2,3-b] pyridine-2-carboxylic acid ethyl ester, this is an organic compound. Its physical and chemical properties are quite important and related to many practical applications.
First of all, the appearance of this compound is often white to light yellow crystalline powder, which is convenient for observation and preliminary identification. From the perspective of melting point, it has a specific melting point range, which can be used for purity detection. If there are many impurities, the melting point will decrease and the melting range will become wider; the melting point of pure people is relatively fixed, such as around [X] ℃, this temperature value is of great significance for identification and quality control.
Solubility is also a key property. It has good solubility in organic solvents such as dichloromethane and N, N-dimethylformamide. Due to the interaction between specific groups in the molecular structure and organic solvents, it is similar to dissolve. But it has poor solubility in water because its molecular polarity does not match water.
Chemical stability is relatively stable under conventional conditions. However, the bromine atom in its structure is highly active and prone to substitution reactions when encountering nucleophiles. The conjugation system of pyridine ring and pyrrole ring makes the molecule have certain aromaticity. When participating in the reaction, electrophilic substitution can occur at specific positions on the ring. At the same time, ester groups can also participate in hydrolysis, alcoholysis and other reactions. When encountering acids or bases, the hydrolysis rate is different. The reaction under acid catalysis is mild, and the hydrolysis is rapid when catalyzed by bases.
These physical and chemical properties, whether used as intermediates in organic synthesis or in drug development, are all key considerations, and are of great significance for research and practice in related fields.

Today there is 1H - Pyrrolo [2,3 - b] pyridine - 2 - carboxylic acid, 4 - bromo -, ethyl ester. It is difficult to tell how the price is in the market. In the market, prices are volatile and often change due to various reasons.
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