1H-Pyrazolo[4,3-b]pyridine,3-methyl-(9CI)

1H-pyrazolo [4,3-b] pyridine-3-methyl (9CI) is an organic compound with unique chemical properties and is quite important.
Looking at its structure, this compound contains a pyrazolo-pyridine core skeleton with 3-methyl as a substituent. This structure endows it with specific physical and chemical properties.
In terms of chemical activity, the nitrogen atom exists in the structure of pyrazolo-pyridine, which has a certain alkalinity. The lone pair electrons on the nitrogen atom can participate in chemical reactions, such as reacting with acids to form salts. This property is of great significance in medicinal chemistry. After forming salts, it can improve the solubility and stability of compounds and is conducive to the development of pharmaceutical preparations.
Furthermore, the 3-methyl substituent affects the distribution and spatial structure of the molecular electron cloud. Methyl is the power supply group, which can change the electron cloud density of the pyridine ring, which affects the activity of electrophilic substitution and nucleophilic substitution. At the same time, the steric hindrance will affect the intermolecular interaction and reaction selectivity. For example, in some reactions, the methyl steric hindrance will reduce the reactivity at a specific position, resulting in changes in the reaction selectivity.
In addition, the compound may participate in various organic reactions, such as halogenation reactions, where halogen atoms can replace hydrogen atoms on the pyridine ring; oxidation and reduction reactions may also occur, changing the oxidation state of some functional groups in the molecule and generating new derivatives, providing diverse possibilities for organic synthesis and drug development.
In the field of organic synthesis, 1H-pyrazolo [4,3-b] pyridine-3-methyl (9CI) is often used as a key intermediate. Due to its unique structure and chemical properties, complex organic molecular structures can be constructed through various reactions, laying the foundation for the synthesis of new drugs and materials.

1H-pyrazolo [4,3-b] pyridine-3-methyl (9CI) is useful in various fields today. In the field of medicinal chemistry, it is often a key intermediate for the creation of new drugs. Due to its unique molecular structure, it can be combined with specific targets in organisms. By modifying its surrounding groups, chemists can develop highly active and highly selective drugs, such as therapeutic drugs for specific diseases, or can precisely intervene in cell signaling pathways for therapeutic purposes.
In the field of materials science, this compound has also emerged. Due to its special electronic structure and physicochemical properties, it may be used to prepare functional materials, such as organic Light Emitting Diode (OLED) materials. In this material, it may optimize luminous efficiency and prolong device life, contributing to the development of display technology.
Furthermore, in the field of organic synthetic chemistry, 1H-pyrazolo [4,3-b] pyridine-3-methyl (9CI) is an important cornerstone for the construction of complex organic molecules. With a variety of synthetic methods, chemists can use it as a starting material to prepare complex and functionally specific organic compounds through multi-step reactions, expanding the boundaries of organic synthesis and providing a richer material basis for the development of new materials and drugs.

The synthesis of 1H-pyrazolo [4,3-b] pyridine-3-methyl (9CI) is an important research direction in the field of organic synthesis. The synthesis method can be achieved by various paths.
First, the compound containing the pyridine structure is used as the starting material. First, a suitable functional group is introduced through a substitution reaction at a specific position of the pyridine ring, which must be able to echo the construction of the pyrazole ring in the subsequent reaction. Subsequently, the pyrazole ring structure is constructed by a cyclization reaction. During the cyclization reaction, the reaction conditions, such as temperature, catalyst type and dosage, need to be precisely regulated. If the temperature is too high or too low, the reaction may be biased towards side reactions, or the reaction rate may be uncomfortable. The choice of catalyst has a great impact on the process of the reaction and the purity of the product. The specific catalyst can effectively promote the formation of pyrazole rings and inhibit unnecessary side reactions.
Second, the pyrazole structure can also be used. First, the pyrazole is modified to introduce active groups that can be connected to the pyrazole ring. Then, with suitable reaction conditions, the pyrazole is connected to the pyridine-containing related fragments to form the target product. In this process, the selection of active groups and the control of the reaction activity are particularly critical. If the activity is too high, it is easy to cause excessive reactions and generate complex by-products; if the activity is too low, the reaction is difficult to proceed.
During the synthesis process, it is also indispensable to monitor the purity of the intermediate and final products of the reaction. The reaction process is often monitored in real time by means of thin layer chromatography, high performance liquid chromatography, etc., to ensure that the purity and structure of the product meet expectations. In this way, through multi-step delicate design and precise regulation of the reaction, 1H-pyrazolo [4,3-b] pyridine-3-methyl (9CI) can be successfully synthesized.

I don't know where the city of 1H - Pyrazolo [4,3 - b] pyridine, 3 - methyl - (9CI) is. This is a well-known city, and it is related to the city, or it may vary depending on the supply and demand of the product, source, quantity, and market.
If you want to know the city, you can go to the factory to supply and sell it. In today's world, there are many chemical product merchants, and they also have official websites on the road, or you can log in to check and sell it.
In addition, the chemical trading platform may also have this quality, which can be searched and compared with more than one person, so as to estimate its approximate market value. However, such prices are often uncertain, and it needs to be observed according to the transformation of the next market.

The safety and toxicity of 1H-pyrazolo [4,3-b] pyridine-3-methyl (9CI) are related to human life and cannot be ignored. However, in ancient literature, there is no direct record of this substance. Although there is no ready-made text, it can be deduced from common sense and the properties of other substances.
Most chemical substances need to be carefully regarded. Organic compounds have complex structures and have different reactivity and biological activity. Nitrogen-containing heterocyclic compounds such as 1H-pyrazolo [4,3-b] pyridine-3-methyl have certain chemical activity due to the existence of nitrogen atoms. In terms of safety, or during storage and transportation, avoid high temperatures, open flames, strong oxidants, etc., to prevent accidental chemical reactions, such as combustion, explosion, etc.
Discuss toxicity, or there are various possibilities. Or because its structure is similar to some active substances in the body, after entering the organism, it interacts with biological macromolecules such as proteins, nucleic acids, etc., interfering with normal physiological and biochemical processes. If it enters the human body, it may be absorbed through the skin, inhaled by the respiratory tract, ingested by mistake, etc. Skin contact may cause allergies, irritation, etc.; inhalation may damage the respiratory system, causing cough, asthma, or even more serious lesions; ingestion may harm the digestive system, causing vomiting, diarrhea, and even life-threatening.
Although the above are all inferences, such unknown and detailed chemicals should be treated with caution, such as the treatment of all substances in "Tiangong Kaiwu". In practical applications, sufficient research and testing must be carried out to clarify their safety and toxicity before they can be used reasonably to avoid harming people and pests.