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What are the physical properties of 1H-pyrazolo [3,4-c] pyridine, 5-chloro-
5-Chloro-1H-pyrazolo [3,4-c] pyridine. The physical properties of this compound are as follows:
Its appearance is often a crystalline solid, and the color may be white to off-white. It is quite stable at room temperature and pressure. In terms of melting point, it is about a specific temperature range, but it varies slightly due to the preparation method and purity. Its solubility is very critical. It has a certain solubility in common organic solvents, such as methanol and ethanol, due to the interaction between the molecular structure of the compound and the organic solvent. In polar organic solvents, intermolecular forces, such as hydrogen bonds, van der Waals forces, etc., can be used to achieve dissolution. In water, the solubility is relatively limited, and the cap is poorly matched with water due to its molecular polarity.
Its density is also one of the important physical properties. After accurate determination, it has a certain value, reflecting the compactness of its internal structure. In addition, the vapor pressure of the compound is low, and at room temperature, the tendency to volatilize is not significant. This property is very important for the consideration of its storage and use environment. Because it is not easy to volatilize, it can better maintain its own chemical integrity under conventional storage conditions.
These physical properties are of crucial significance in the synthesis, separation, purification and practical application of the compound, and can provide a solid theoretical basis for the design of related chemical operations and industrial processes.
What are the chemical properties of 1H-pyrazolo [3,4-c] pyridine, 5-chloro-
5-Chloro-1H-pyrazolo [3,4-c] pyridine, this is an organic compound. Its chemical properties are unique and contain many wonders.
Looking at its structure, it is formed by the combination of pyrazole and pyridine, and chlorine atoms are introduced at the 5th position. This chlorine atom is like the finishing touch, which greatly affects the properties of the compound.
In terms of physical properties, it usually appears as a solid with a specific melting point and boiling point. Due to the nitrogen heterocycle in the structure, there is a strong interaction between molecules, resulting in a relatively high melting point.
When it comes to chemical properties, the nitrogen atom on the pyridine ring and the pyrazole ring in this compound is rich in solitary pairs of electrons, showing a certain alkalinity, which can react with acids to form corresponding salts. The chlorine atom has high activity and can participate in the nucleophilic substitution reaction. Under suitable conditions, the nucleophilic reagent can attack the carbon atom connected to the chlorine, and the chlorine atom leaves to form a new compound. This reaction has a wide range of uses in the field of organic synthesis.
In addition, due to the existence of a conjugate system, the compound also has certain optical properties and electronic properties, which may have potential applications in optoelectronic devices and other fields.
Furthermore, its reactivity and selectivity are affected by factors such as substituents and reaction conditions. Through careful regulation of these factors, specific chemical reactions can be achieved, laying the foundation for the synthesis of more complex organic compounds.
In short, 5-chloro-1H-pyrazolo [3,4-c] pyridine is rich in chemical properties and has broad potential applications in many fields such as organic synthesis and materials science, waiting for people to explore and dig deeper.
What is the main use of 1H-pyrazolo [3,4-c] pyridine, 5-chloro-?
5-Chloro-1H-pyrazolo [3,4-c] pyridine has a wide range of uses. In the field of medicine, it is often a key intermediate for the creation of new drugs. Due to its unique chemical structure, it can closely bind to specific biological targets, helping to develop specific drugs for specific diseases. For example, in the research of anti-tumor drugs, modified and modified, it can precisely act on tumor cell-related targets, interfering with tumor cell growth, proliferation and metastasis, and bringing new opportunities to overcome tumor diseases.
In the field of pesticides, 5-chloro-1H-pyrazolo [3,4-c] pyridine also plays an important role. With its special activity against certain pests or pathogens, high-efficiency, low-toxicity and environmentally friendly pesticides can be developed. Such pesticides can precisely target pests, reduce the harm to beneficial organisms and the environment, and are of great significance to ensuring a bumper crop harvest and maintaining ecological balance.
In the field of materials science, its unique structure endows special physical and chemical properties, or can be used to prepare materials with special properties. For example, in the field of photovoltaic materials, through rational design and synthesis, it is expected to develop new materials with excellent photoelectric conversion efficiency, injecting new impetus into the development of photovoltaic devices such as solar cells. In short, 5-chloro-1H-pyrazolo [3,4-c] pyridine has important application value and broad development prospects in many fields.
What are the synthesis methods of 1H-pyrazolo [3,4-c] pyridine, 5-chloro-
The synthesis method of 1H-pyrazolo [3,4-c] pyridine-5-chlorine, although the synthesis of such specific compounds is not directly recorded in the ancient book "Tiangong Kaiwu", the chemical process ideas contained in it may be enlightening for its synthesis.
Looking at "Tiangong Kaiwu", the preparation of various substances follows a step-by-step and exquisite preparation method. To synthesize this compound, you can start from the basic raw materials first. The compound containing the pyridine structure is used as the initial substrate, and the pyridine ring has stable aromatic properties. Chlorine atoms can be introduced into the pyridine ring at the appropriate position by halogenation reaction. This step requires precise control of the reaction conditions, such as temperature, reaction time, and the amount of halogenated reagents. If the temperature is too high, it may cause excessive halogenation or damage to the structure of the pyridine ring; if the temperature is too low, the reaction rate will be slow and the yield will be poor.
As for the construction of the pyrazole ring, the nitrogen-containing compound and an appropriate carbon source can be selected according to the idea of constructing a complex structure in Tiangong Kaiwu. Take advantage of the nucleophilicity of the nitrogen atom in the nitrogen-containing compound to condensate with the carbon source. In the reaction, a suitable catalyst may be required to promote the reaction, and the influence of the catalyst on the selectivity of the reaction needs to be considered, and the pyrazole ring should be constructed at a specific position of the pyridine ring to generate the target pyrazolo [3,4-c] pyridine structure. In the
reaction process, each step needs to be carefully monitored and regulated. "Tiangongkai" also emphasizes the control of the process. Modern analytical methods, such as thin-layer chromatography, nuclear magnetic resonance, etc., can be used to monitor the reaction process and product purity. After each step of the reaction, properly handle the reaction mixture, separate and purify the product, remove impurities, and provide pure raw materials for the next reaction. In this way, following scientific and reasonable steps and referring to the process ideas of "Tiangongkai", an effective synthesis of 1H-pyrazolo [3,4-c] pyridine-5-chloride can be achieved.
What is the price range of 1H-pyrazolo [3,4-c] pyridine, 5-chloro in the market?
I don't know if 1H - pyrazolo [3,4 - c] pyridine, 5 - chloro - is in the market price range. This is a more professional chemical substance, and its price is determined by many factors. First, the purity is extremely critical, and the price of high purity must be higher than that of low purity. Second, the difficulty of the production process is different. If the process is complicated and the cost rises, the price is also high. Third, the market supply and demand situation has a great impact. If demand is strong and supply is scarce, the price will rise; conversely, if supply exceeds demand, the price may fall. Fourth, different suppliers have different pricing strategies, which also lead to differences in prices.
If you want to know the exact price range, you can explore it from the following ways. First, consult professional chemical reagent suppliers, such as Sinopharm Group Chemical Reagent Co., Ltd., which often provide price information for various chemical products. Second, consult professional chemical product e-commerce platforms, such as Gade Chemical Network, etc., many merchants publish product prices on it, which can be used as a reference. Third, seek help from scientific research institutions and university chemical laboratory personnel, who may know the price range of this substance due to experimental purchases. Unfortunately, it is difficult for me to understand the specific price range at this moment. You can follow the above method and explore it in detail to get accurate price information.