1h Pyrazolo 3 4 B Pyridine
pyridine pyrrole pyrazine piperidine piperazine

1H-pyrazolo[3,4-b]pyridine

    Specifications

    HS Code

    496764

    Chemical Formula C7H6N4
    Molar Mass 146.15 g/mol
    Appearance Solid
    Melting Point 160 - 163 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like DMSO, DMF
    Uv Absorption Absorbs in the UV region, specific λmax depends on substitution

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    General Information
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    Frequently Asked Questions

    As a leading 1H-pyrazolo[3,4-b]pyridine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1H-pyrazolo [3,4-b] pyridine?
    1H-pyrrolido [3,4-b] pyridine has a wide range of uses. In the field of medicinal chemistry, it is a key organic synthesis intermediate. Many drug research and development are based on it. By modifying its structure, compounds with diverse biological activities can be obtained for the treatment of various diseases such as cancer and neurological diseases.
    In the field of materials science, 1H-pyrrolido [3,4-b] pyridine also exhibits unique properties. It can participate in the preparation of materials with special photoelectric properties. In the fields of organic Light Emitting Diode (OLED) and solar cells, it is expected to improve the photoelectric conversion efficiency and stability of materials, and then promote the development of related technologies.
    In the field of pesticide chemistry, compounds synthesized from this raw material may have good insecticidal and bactericidal activities. Can develop high-efficiency, low-toxicity and environmentally friendly pesticide products, providing assistance for agricultural pest control.
    Furthermore, in organic synthetic chemistry, 1H-pyrrolido [3,4-b] pyridine is often used as a key synthetic block due to its unique structure and reactivity. Chemists can use various chemical reactions to connect it with other functional groups or molecular fragments to construct complex organic compounds, injecting vitality into the development of organic synthetic chemistry.
    In conclusion, 1H-pyrrolido [3,4-b] pyridine has important application value in many important fields due to its unique structure and properties. With the continuous progress of science and technology, its application prospects will also be broader.
    What are the synthesis methods of 1H-pyrazolo [3,4-b] pyridine
    The synthesis method of 1H-pyrrolido [3,4-b] pyridine is a key research topic in the field of organic synthesis. Its synthesis paths are diverse, each has its own advantages, and varies according to different starting materials and reaction conditions.
    First, the synthesis method using pyridine derivatives as starting materials is quite common. Under specific reaction conditions, pyridine derivatives react with suitable reagents, and after key steps such as cyclization, the core skeleton of pyrrolido [3,4-b] pyridine can be constructed. In this process, the precise regulation of reaction conditions is crucial, such as temperature, pH, and the choice and dosage of catalysts, all of which have a profound impact on the reaction process and product yield.
    Second, there are also those who use pyrrole derivatives as starting materials. By ingeniously designing the reaction route, pyrrole derivatives can react with specific reagents to gradually build the target molecular structure. This approach also requires careful consideration of each reaction step to ensure that the reaction proceeds in the expected direction and obtains high-purity products.
    Furthermore, the synthesis strategy of transition metal catalysis has also attracted much attention. Transition metal catalysts often exhibit unique catalytic properties in organic synthesis, which can effectively promote the reaction progress, improve the reaction efficiency and selectivity. In the synthesis of 1H-pyrrolido [3,4-b] pyridine, transition metal catalysis can achieve some reactions that are difficult to achieve by traditional methods, providing a novel and efficient way for synthesis.
    In addition, there are also those who synthesize 1H-pyrrolido [3,4-b] pyridine through multi-component reaction. The multi-component reaction has the advantages of simple operation and high atomic economy, and can react a variety of raw materials in one step to construct complex molecular structures. However, this method also faces challenges such as complex reaction conditions and difficulty in product separation and purification.
    There are many methods for synthesizing 1H-pyrrolido [3,4-b] pyridine, and the advantages and disadvantages of each method coexist. Chemists need to carefully choose a suitable synthesis path according to their own needs, raw material availability, and experimental conditions, in order to achieve the purpose of efficient and high-purity synthesis.
    What are the physicochemical properties of 1H-pyrazolo [3,4-b] pyridine?
    1H-pyrrolido [3,4-b] pyridine is a kind of organic compound. Its physical and chemical properties are particularly important and are related to applications in many fields.
    In terms of its physical properties, under normal temperature and pressure, 1H-pyrrolido [3,4-b] pyridine is often in a solid state, but this is uncertain and depends on changes in the surrounding environment. Its melting point, which is a key parameter for measuring the transformation of its physical state, has been experimentally measured and has a specific value. This value is very useful in the purification and separation of substances. And its solubility also has characteristics. It can show good solubility in some organic solvents, such as common ethanol and dichloromethane, but its solubility in water is relatively limited. This property allows chemists to consider when choosing a reaction solvent to meet the needs of the reaction.
    As for chemical properties, in the molecular structure of 1H-pyrrolido [3,4-b] pyridine, the pyridine ring and the pyrrole ring are conjugated to each other, giving it a unique electron cloud distribution. This structure makes it aromatic, and in chemical reactions, it can participate in a variety of electrophilic substitution reactions. In case of electrophilic reagents, hydrogen atoms at specific positions on the ring are easily replaced to generate novel derivatives. Furthermore, the lone pair of electrons on the nitrogen atom makes the compound have a certain alkalinity, which can neutralize with acids to generate corresponding salts. This acid-base property has a great impact on the field of medicinal chemistry, because the acid-base interaction between drugs and the environment in the body is related to the development of drug efficacy.
    The physicochemical properties of 1H-pyrrolido [3,4-b] pyridine have laid a solid foundation for its application in organic synthesis, drug research and development, etc. Chemists can design and synthesize desired compounds according to their characteristics to meet different needs.
    What is the market price of 1H-pyrazolo [3,4-b] pyridine?
    1H-pyrrolido [3,4-b] pyridine, an organic compound, is quite useful in many fields, but it is difficult to generalize its market price, because many factors are intertwined, which affects its price.
    The difficulty of its preparation is one of the key effects of price. If the preparation requires complicated steps, rare raw materials or special conditions, the cost will be high, and the price will also rise. For example, the preparation process requires strict temperature and pressure control, or relies on rare reagents, which all lead to higher costs.
    Furthermore, market demand and supply trends also affect the price. If the market demand for this compound is strong at a certain time, but the supply is limited, according to the reason of supply and demand, the price will go up; on the contrary, if the demand is low and the supply is abundant, the price will tend to decline.
    The purity of 1H-pyrrolido [3,4-b] pyridine is difficult to prepare and the use is more specialized, so the price is often far higher than that of ordinary purity. If used in high-end pharmaceutical research and development, the purity requirements must be extremely high, and such high-purity products are expensive.
    In addition, the cost structure of the manufacturer, transportation and storage conditions, etc., also play a role in the price. The technical level and operating costs of different manufacturers are different, and the price may be different; and those who require special transportation and storage conditions, such as low temperature, protection from light, etc., also increase the cost and affect the selling price.
    In summary, the market price of 1H-pyrrolido [3,4-b] pyridine fluctuates due to difficulty in preparation, supply and demand, purity and other related factors. To know the exact price, it is necessary to consider the specific market situation and transaction details in detail.
    What are the related research advances of 1H-pyrazolo [3,4-b] pyridine?
    1H-pyrrolido [3,4-b] pyridine, which is related to many research progress. In the field of organic synthesis, chemists continue to study new paths to improve yield and purity. In the past, the synthesis method may have the disadvantages of complicated steps and harsh conditions, but now there are more concise and efficient methods emerging. Some scholars have greatly simplified the synthesis process and significantly improved the yield by using new catalysts and optimized reaction conditions.
    In the field of medicinal chemistry, 1H-pyrrolido [3,4-b] pyridine has a unique structure and potential biological activity. Scientists are committed to exploring new drugs with this core structure. Many studies have shown that compounds containing this structure exhibit good inhibitory or activating effects on specific disease targets, and are expected to be developed into new drugs such as anti-cancer and anti-virus.
    In the field of materials science, it has also attracted attention. Due to its special electronic structure and physical properties, it can be used to prepare new functional materials. For example, it can be used in organic optoelectronic materials, which may improve the photoelectric conversion efficiency and stability of materials, adding new possibilities for the development of optoelectronic devices.
    Other scholars have focused on the study of its derivatives and expanded its application range and properties through modification and derivatization. These research advances pave the way for the future development of 1H-pyrrolido [3,4-b] pyridine, which may lead to new changes and breakthroughs in many fields.