1H-Pyrazolo[3,4-b]pyridine-5-carbonitrile

1H-pyrazolo [3,4-b] pyridine-5-formonitrile is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry. In the process of many drug research and development, new drugs with specific biological activities can be created by modifying and modifying their structures.
In the field of pesticides, 1H-pyrazolo [3,4-b] pyridine-5-formonitrile also has potential application value. It may be appropriately derived and converted into pesticide products with high insecticidal, bactericidal or herbicidal properties, which can help agricultural pest control and improve crop yield and quality.
Furthermore, in the field of materials science, the compound may be applied to the preparation of organic optoelectronic materials due to its own unique structure and properties. After rational design and synthesis, it may endow the material with special optical and electrical properties, and make a name for itself in the manufacturing of Light Emitting Diodes, solar cells and other devices.
In summary, 1H-pyrazolo [3,4-b] pyridine-5-formonitrile has important uses in many fields such as medicine, pesticides and materials science, and plays a key role in promoting technological development and innovation in various fields.

The synthesis methods of 1H-pyrazolo [3,4-b] pyridine-5-formonitrile have been around for a long time, and there are many kinds.
One method is to use the corresponding pyridine derivative as the starting material. First, the pyridine derivative and a specific nitrogen-containing reagent are condensed in a suitable solvent under mild heating and alkali catalysis. This base such as potassium carbonate and the solvent such as dimethylformamide complement each other to promote the smooth reaction and generate key intermediates. Subsequently, the intermediate undergoes a cyclization reaction. By precisely regulating the reaction temperature and time, supplemented by suitable catalysts, such as some transition metal salts, the internal structure of the molecule is rearranged and cyclized, resulting in 1H-pyrazolo [3,4-b] pyridine-5-formonitrile.
There is another method, starting from pyrazole compounds. With suitable pyrazoles as raw materials, they are first functionalized and modified to introduce specific substituents. Halogen atoms, such as bromine atoms, are introduced at specific positions on the pyrazole ring by halogenation reaction. Then, coupling reactions occur with cyanopyridine derivatives under palladium catalysis. The reaction system needs to be strictly anhydrous and oxygen-free. Palladium catalysts such as tetrakis (triphenylphosphine) palladium, with suitable ligands, react at a specific temperature to make the two molecules skillfully combine. After subsequent refining steps, the target product can also be obtained.
Furthermore, the target molecular skeleton can be constructed from simple and easy-to-obtain raw materials through multi-step reactions. First, use common organic reagents through nucleophilic substitution, addition and other basic reactions to gradually build a molecular framework. For example, nitrile compounds react with active olefins under specific conditions to form a preliminary structure. After multi-step functional group conversion, including oxidation, reduction, cyclization and other steps, each step requires careful control of the reaction conditions, such as temperature, pH, reactant ratio, etc., and finally successfully synthesize 1H-pyrazolo [3,4-b] pyridine-5-formonitrile. These synthesis methods have their own advantages and need to be followed according to actual needs and conditions.

1H-pyrazolo [3,4-b] pyridine-5-formonitrile, the physical properties are related to its shape, melting boiling, solubility, and stability.
Looking at its shape, under normal conditions, 1H-pyrazolo [3,4-b] pyridine-5-formonitrile is mostly white to off-white powder, fine and uniform, and the quality is visible.
As for the number of melting boiling, its melting point is quite considerable, about within a certain temperature range. This value is its inherent property, due to intermolecular forces and crystal structure. Under the hot topic, it can be seen that it melts, showing the stability of the structure. The boiling point is higher, reaching a specific temperature, from liquid to gaseous state, after a phase change, this process requires a sufficient amount of energy to break the binding between molecules.
Talking about solubility, among common organic solvents, 1H-pyrazolo [3,4-b] pyridine-5-formonitrile has different behaviors. In polar organic solvents, such as methanol and ethanol, it is slightly dissolved, and the molecules and solvents interact with hydrogen bonds and other forces; in non-polar solvents, such as n-hexane, toluene, etc., it dissolves very little, because the forces between the two molecules are quite different.
Stability is also key. 1H-pyrazolo [3,4-b] pyridine-5-formonitrile is relatively stable at room temperature and pressure, and the chemical bonds in the molecular structure are firm. In case of extreme conditions such as strong acid, strong base or high temperature and light, the structure may change, triggering chemical reactions and causing changes in properties.
In summary, the physical and chemical properties of 1H-pyrazolo [3,4-b] pyridine-5-formonitrile are of great significance in many fields such as organic synthesis and drug development, and are the basis for related research and application.

I look at your question, but I am inquiring about the market price of 1H-pyrazolo [3,4-b] pyridine-5-formonitrile. However, the price of this chemical product is not static and is determined by many factors.
First, the price varies depending on the purity. If it is high purity, it is suitable for high-end fields such as fine chemical experiments or pharmaceuticals, and the price must be high; if the purity is slightly lower, it is used for general basic research, and the price may be slightly lower.
Second, the purchase quantity is also related to the price. If you buy in bulk, the supplier may give a discount due to economies of scale; if you buy only a small amount, the price may be higher to meet sporadic demand.
Third, the state of market supply and demand has a deep impact. If the demand for this product is strong and the supply is limited, the price will tend to rise; conversely, if the supply exceeds the demand, the price will drop.
Fourth, the manufacturer and the source are different, and the price is also different. Well-known large factories, due to quality control and brand reputation, the price may be high; small factories produce, the price may be competitive. And different origins, transportation costs, etc. also affect their final selling price.
Due to the unpredictable market, it is difficult to determine its price. For the actual price, you can consult the chemical reagent supplier, or check it on the chemical product trading platform, and you can get a more accurate price.

1H-pyrazolo [3,4-b] pyridine-5-formonitrile is produced by many manufacturers. In today's chemical and pharmaceutical industry, many manufacturers are involved in the production of this compound.
In China, there are pharmaceutical companies specializing in the research and production of heterocyclic compounds. Such manufacturers have devoted themselves to the manufacture of 1H-pyrazolo [3,4-b] pyridine-5-formonitrile with exquisite technology and complete equipment. In the study of technology, they strive to improve in order to achieve high-quality production.
There are also various factories overseas. With profound background and cutting-edge technology, they have also made considerable achievements in the production of this compound. They recruit talents, explore new ways, and improve product quality and yield with good intentions.
There may be small enterprises, although the scale is not large, in specific fields, they can also produce high-quality 1H-pyrazolo [3,4-b] pyridine-5-formonitrile. Its focus is one corner, and it has won a place in the market with its characteristic method.
There are also production units affiliated to scientific research institutes. According to its strong scientific research strength, the research results are converted into actual output. The 1H-pyrazolo [3,4-b] pyridine-5-formonitrile produced by them often has unique advantages.
All these things are more. Each manufacturer applies its own capabilities to promote the production and development of 1H-pyrazolo [3,4-b] pyridine-5-formonitrile.