1H-pyrazolo[3,4-b]pyridine, 5-bromo-3-iodo-

5-Bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine, this compound has important applications in many fields. In the field of medicinal chemistry, it is often used as a key intermediate. By means of organic synthesis, complex molecular structures with specific biological activities can be carefully constructed. The skeleton structure of geinpyrazolo-pyridine shows a unique affinity with biological targets in drug development and can influence specific biological processes. For example, for certain disease-related protein kinases, such compounds may be designed as highly effective inhibitors, thereby modulating cell signaling pathways and opening up new avenues for disease treatment.
In the field of materials science, 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine also has potential uses. Due to the special electronic properties imparted by its molecular structure, it may be applied to the creation of organic optoelectronic materials. After rational molecular design and modification, the compound may become an active material component in organic Light Emitting Diode (OLED) or organic solar cells, contributing greatly to the improvement of photoelectric conversion efficiency and stability of materials.
Furthermore, in the field of pesticide chemistry, it may also emerge. With in-depth research on the relationship between its structure and activity, new and efficient pesticides may be developed, which have specific biological activities against pests and are relatively friendly to the environment, contributing to sustainable agricultural development.
In short, 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine has broad application prospects in many fields such as medicine, materials, and pesticides. With the continuous deepening of research, it is expected to bring new breakthroughs and development to these fields.

To prepare 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine, there are various methods. It is described in the ancient method today.
First, it can be obtained by bromination of pyrazolo [3,4-b] pyridine and then iodization. At the time of bromination, use a suitable brominating agent, such as liquid bromine or N-bromosuccinimide (NBS), under suitable reaction conditions, such as in an organic solvent, control the temperature to replace the bromine atom in a specific position of the pyridine ring to obtain 5-bromo-1H-pyrazolo [3,4-b] pyridine. Then, an iodine agent, such as potassium iodide, works synergistically with a suitable oxidizing agent to introduce iodine atoms, resulting in 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine.
Second, you can also iodize first and then bromide. In the iodization step, choose a suitable iodine source and catalyst to promote the integration of iodine atoms in a specific solvent and reaction environment. After the bromination reaction, through these two steps, the target product can also be reached.
Third, the one-pot method can also be used. That is, carefully select the appropriate reagent combination, so that the bromination and iodization reactions occur in the same reaction system in sequence, without the need to separate the intermediate product. In this way, reducing the operation steps may improve the yield. However, this method requires high control of the reaction conditions, and factors such as temperature, reagent ratio and reaction time need to be precisely regulated to ensure that the reaction proceeds according to the expected path to obtain a pure 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine product.

5-Bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine is a kind of organic compound. Its physical and chemical properties are worth exploring.
Looking at its physical properties, under normal circumstances, the substance may be in a solid state, but the specific color state may vary depending on the purity and crystal form, or in a white to light yellow powder or crystalline state. The determination of its melting point is of great significance in exploring its thermal stability and purity. The value of the melting point can be measured by differential scanning calorimetry and other techniques. This value is an important basis for identifying the compound and evaluating its purity.
As for chemical properties, the presence of bromine and iodine atoms in its molecular structure endows the compound with unique reactivity. Bromine and iodine atoms are halogen atoms with strong electronegativity and are prone to nucleophilic substitution. Under appropriate reaction conditions, halogen atoms can be replaced by other nucleophilic reagents, such as hydroxyl groups, amino groups, etc., to form new carbon-heteroatom bonds, providing the possibility for the synthesis of organic molecules with more complex structures. At the same time, the parent nuclear structure of pyrazolo [3,4-b] pyridine has a certain alkalinity due to nitrogen atoms, which can react with acids to form salts. This property may have application value in the field of medicinal chemistry to improve the solubility and stability of compounds. And the conjugated structure of the compound makes it have potential applications in the fields of light and electricity, such as participating in photochemical reactions, showing unique optical properties.

I am looking at your inquiry, but it is the market price of 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine. However, the market price often changes due to many reasons, such as supply and demand, quality differences, purchase quantities, differences in sellers, and even differences in time and place, which can cause its price to fluctuate.
In the chemical raw material market, if this product is common and mass-produced, its price may be relatively affordable. Large-scale production can reduce its unit cost, the market supply is sufficient, competition is also fierce, and the price will decrease. However, if the preparation of this product is difficult, requires complex processes, rare raw materials, or the market demand is small but specific, the price may be high.
And the purchase volume is also the key. If the purchase volume is huge, the seller may give a discount due to the idea of small profits but quick turnover, and the total price will be reduced. On the contrary, only a small amount is purchased, or the unit price is higher due to cost considerations such as packaging and transportation.
In addition, different merchants also have different pricing. Well-known large factories, because of their excellent brand reputation and quality control, may have high prices; while small factories or new factories, in order to compete for market share, the price may be more close to the people.
As for the exact price, it is difficult to say in a word. If you want to know the details, you can consult chemical product suppliers, traders, or search on the chemical product trading platform to obtain more accurate price information.

There are many derivatives of 1H-pyrazolo [3,4-b] pyridine, 5-bromo-3-iodine-this substance. Its derivation path often involves chemical synthesis, and different products can be produced by many reactions.
Such as nucleophilic substitution reaction, because the bromine and iodine atoms in this compound are quite active, it is easy to interact with nucleophiles. If you encounter nitrogen-containing nucleophiles, such as amines, new carbon-nitrogen bonds can be formed to obtain nitrogen-containing derivative products. Such products may have potential uses in the field of medicinal chemistry, because nitrogen atoms can participate in molecular interactions and affect the biological activity of compounds. < Br >
can also carry out metal-catalyzed coupling reactions. Taking the cross-coupling reaction catalyzed by palladium as an example, 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine can be coupled with organoboronic acids or halogenated hydrocarbons to construct compounds with more complex structures. The derived products may have applications in materials science and can be used to prepare materials with special photoelectric properties.
In addition, its structure can be changed by reduction reaction. For example, bromine and iodine atoms are reduced and removed to obtain 1H-pyrazolo [3,4-b] pyridine derivatives with simplified structures. Such products may play a role in studying the basic properties of such compounds, helping researchers to clarify the relationship between their structures and properties.
Furthermore, it can be cyclized. Using intramolecular interactions between atoms to construct new cyclic structures to generate derived products with unique spatial configurations. Such products may be of great significance in the field of total synthesis of natural products, providing key intermediates for the synthesis of complex natural products.
In summary, 5-bromo-3-iodine-1H-pyrazolo [3,4-b] pyridine can be derived from a variety of chemical reactions, resulting in a wide range of products with different structures and uses, which are of great value in various scientific research fields.