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What is the chemical structure of 1H-octahydropyrrolo [3,4-b] pyridine?
1H-octahydro pyrrole [3,4-b] pyridine, its chemical structure is also. This is one of the organic compounds, with a specific atomic connection mode and spatial arrangement.
In terms of its name, "pyrrole" indicates that its structure contains pyrrole ring and other ring phase merger. "[3,4-b]" is the position of merger between standard rings. For octahydro, it is said that the partially unsaturated bond on the ring is hydrogenated and saturated, that is, on the basis of the pyrrole structure, multiple carbon-carbon double bonds are hydrogenated, which is in the shape of octahydro.
The part of pyridine is a six-membered nitrogen-containing heterocycle, which is aromatic. After combining with pyrrole, the overall structure is more complex and unique. This structure endows the compound with specific physical and chemical properties, which may have important uses in organic synthesis, medicinal chemistry and other fields. Due to the specific structure, it may have a unique electron cloud distribution, which affects its reactivity and selectivity. In drug development, it may interact specifically with biological targets and exhibit specific pharmacological activities.
What are the physical properties of 1H-octahydropyrrolo [3,4-b] pyridine
1H-octahydropyrrolido [3,4-b] pyridine, having various physical properties. It is an organic compound, under normal conditions, either in a liquid state or a solid state, but the specific form depends on the temperature and pressure of the surrounding environment.
Looking at its color, it is often close to colorless, or very light in color, just as clear as water, or slightly yellow. Smell it, or emit a slight smell, but its taste is specific, unlike the common aroma, which seems to be a unique smell of organic compounds.
When it comes to solubility, it can be dissolved in organic solvents, such as ethanol, ether, etc., just like fish get water, and the two are mixed and fused. However, in water, its solubility varies, or it is only slightly soluble, or it is almost insoluble, depending on the characteristics of its molecular structure.
As for the melting point and boiling point, they are also important physical properties. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. The melting point of 1H-octahydro pyrrolido [3,4-b] pyridine varies slightly depending on the purity and measurement conditions, and is probably in a certain temperature range. The boiling point is the temperature at which the liquid is converted into a gas. At this temperature, the internal bubbles of the liquid rise and escape into a gaseous state. The boiling point of this compound also has its specific value, which reflects the strength of its intermolecular forces. < Br >
The density is related to the mass per unit volume. The density of 1H-octahydropyrrolido [3,4-b] pyridine may be different from that of water, or lighter than water and floating on water; or heavier than water and sinking on the bottom, which is also determined by its molecular composition and accumulation mode. All kinds of physical properties are of crucial significance in the study of the properties, separation and purification, and practical application of this compound.
What is the main use of 1H-octahydropyrrolo [3,4-b] pyridine?
1H-octahydropyrrolido [3,4-b] pyridine is one of the organic compounds. It has a wide range of uses and plays a crucial role in the field of medicinal chemistry.
In the process of drug development, this compound is often a key intermediate. Due to its unique chemical structure, it can interact with specific targets in organisms and exhibit diverse biological activities. For example, many drugs developed on its basis can act on the nervous system, affect the transmission of neurotransmitters, and then be used to treat nervous system-related diseases such as depression and anxiety. Or it can regulate the physiological function of the cardiovascular system and play a therapeutic effect on cardiovascular diseases such as hypertension and arrhythmia.
Furthermore, in the field of materials science, 1H-octahydropyrrole [3,4-b] pyridine also has its uses. Its structure can endow materials with specific physical and chemical properties, such as improving the stability and solubility of materials. This helps to prepare new materials with better properties, which may have potential applications in fields such as electronics and optics.
In addition, in organic synthetic chemistry, it is often used as an important synthetic building block. Chemists can modify and derive its structure through various chemical reactions to construct more complex organic molecules, providing many possibilities for the development of organic synthetic chemistry.
In conclusion, 1H-octahydropyrrolido [3,4-b] pyridine, with its unique structure and properties, plays an indispensable role in many fields such as medicine, materials, and organic synthesis, and has made great contributions to the development of related fields.
What are the synthesis methods of 1H-octahydropyrrolo [3,4-b] pyridine
The synthesis method of 1H-octahydro-pyrrolido [3,4-b] pyridine is important in the field of organic synthesis. To make this compound, there are various paths.
First, the structure can be constructed by multi-step reaction from suitable starting materials. For example, starting with a nitrogen-containing heterocycle and a suitable hydrocarbon fragment, the nucleophilic substitution reaction is used to connect the two. In this case, the appropriate base and solvent need to be selected to promote the smooth progress of the reaction. If potassium carbonate is used as a base, in an acetonitrile solvent, the nucleophilic reagent reacts with the halogenated hydrocarbon fragment to form a preliminarily linked intermediate.
Second, a cyclization reaction strategy can also be used. Using chain-like compounds with appropriate functional groups as raw materials, under suitable conditions, the intramolecular ring is formed. In this process, specific catalysts may be required. For example, metal catalysts are used to catalyze the intramolecular cyclization of alkenyl halides and nitrogen-containing nucleophiles. After fine regulation of reaction temperature, time and catalyst dosage, the target product can be obtained.
Furthermore, it can also be achieved by rearrangement reaction. Some compounds with specific structures, under suitable reagents and conditions, undergo intramolecular rearrangement, and then form the structure of 1H-octahydropyrrolio [3,4-b] pyridine. This requires precise grasp of the structure and reaction conditions of the reaction substrate in order to obtain ideal results.
Each method has its own advantages and disadvantages. During synthesis, the appropriate synthesis path should be carefully selected according to the actual situation, such as the availability of raw materials, the difficulty of reaction, and the purity requirements of the product. To efficiently prepare 1H-octahydropyrrolido [3,4-b] pyridine.
What is the price range of 1H-octahydropyrrolo [3,4-b] pyridine in the market?
The price range of 1H-octahydropyrrolido [3,4-b] pyridine on the market is difficult to determine. The price of this compound often varies due to many factors. Its purity is one of the keys. If the purity is high, the price may be high; if it is slightly inferior, the price may be slightly reduced. And the simplicity of its production process also affects the price. The process is complicated, the cost must be high, and the price will rise accordingly; if the process is simple, the price may be slightly cheaper.
Furthermore, the situation of market supply and demand also affects its price. If there are many people who want it, and there are few people who supply it, the price will increase; if the supply exceeds the demand, the price may decrease. And different suppliers, because of their operating costs and marketing strategies, have different pricing.
Looking at various markets, there may be low prices, each gram or only a few yuan; however, there are also high prices due to special needs, which can reach tens of yuan per gram, or even hundreds of yuan. Therefore, in order to determine the exact price, it is necessary to carefully examine the real-time market conditions and consult many suppliers to obtain a more accurate price range.