1H-imidazo[4,5-b]pyridine, 5-bromo-

5-Bromo-1H-imidazolo [4,5-b] pyridine, which has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate, used to create various drugs with special pharmacological activities. For example, when developing targeted therapeutic drugs for specific diseases, its structural characteristics can help the drug to act precisely on the target to achieve therapeutic effect.
In the field of materials science, or can participate in the synthesis of new organic materials. Due to its unique molecular structure, or endowing materials with special properties such as photoelectric properties and thermal stability, it has emerged in the fields of optoelectronic devices, such as organic Light Emitting Diodes, solar cells, etc. < Br >
It is also an important research object at the level of chemical research. Chemists can use various chemical reactions to explore new reaction paths and methods, deepen their understanding of the mechanism of organic chemistry, and then promote the development of organic synthetic chemistry. It is of great value in many fields and provides a key foundation for many scientific research and practical applications.

5-Bromo-1H-imidazolo [4,5-b] pyridine is an organic compound with unique physical properties. It is a solid and stable at room temperature. Looking at its color, or white to light yellow powder, this color is derived from the absorption and reflection characteristics of the molecular structure.
When it comes to the melting point, it has been determined by many experiments that it is about a certain temperature range. This temperature is of great significance to the change of the state of the substance in its synthesis and application. For example, in some reaction systems, when the temperature approaches or reaches the melting point, the substance will change from solid to liquid, which will affect the reaction rate and process.
Its solubility is also an important physical property. In common organic solvents, such as dichloromethane, N, N-dimethylformamide, it exhibits a certain solubility. This is due to interactions such as van der Waals forces and hydrogen bonds between molecules and solvent molecules. In dichloromethane, because the molecular polarity of dichloromethane matches the partial structure of the compound, the two attract each other and dissolve. In water, due to the relatively hydrophobic overall structure of the compound, the interaction between water molecules and compound molecules is weak, so it is difficult to dissolve.
In addition, the compound has a certain density. Although the specific value needs to be accurately measured by instruments, the density affects its distribution and behavior in different media. In the mixed system, depending on the density difference, it is either in the upper layer or at the bottom, which affects the contact and reaction between substances. These physical properties lay the foundation for their applications in organic synthesis, drug discovery, and other fields.

To prepare 5-bromo-1H-imidazolo [4,5-b] pyridine, the following method can be used. First, a suitable pyridine derivative is taken as the starting material, and the structure of this material should contain groups that can be converted into imidazole rings. In the ancient method, nitrogen-containing heterocycles are often reacted with halogenated reagents.
First, the pyridine derivative is mixed with an appropriate amount of brominating reagents, such as bromine or bromine-containing compounds. The reaction must be carried out in a suitable reaction medium, such as organic solvents, such as dichloromethane, chloroform, etc. These solvents can help the reactants to disperse uniformly and promote the smooth occurrence of the reaction. The reaction system needs to be controlled at an appropriate temperature, or at room temperature, or heated, depending on the specific reaction activity. If heating is required, the temperature should be precisely controlled by oil or water bath.
In this process, the bromine atom of the brominating reagent will replace the hydrogen atom at a specific position of the pyridine derivative to obtain the bromine-containing pyridine intermediate. Then, the intermediate is subjected to a cyclization reaction, and suitable cyclization reagents, such as nitrogen-containing base compounds, are often added to promote the cyclization of the molecule to form the structure of imidazolo [4,5-b] pyridine, and then 5-bromo-1H-imidazolo [4,5-b] pyridine is obtained. The whole process requires attention to the precise control of the reaction conditions. The proportion of reactants and reaction time are all related to the purity and yield of the product.

I look at what you are asking, but I am inquiring about the price of 5-bromo-1H-imidazolo [4,5-b] pyridine in the market. However, this price varies from time to time, and also depends on factors such as seller, quality, and quantity.
If you find the price of this chemical in the city of the past, you often need to go through various pharmaceutical stores and chemical materials. Or if there is a company specializing in this, you can ask in detail. However, at that time, the information was not as accessible as it is today, and it was difficult to find the price.
Today is different from the past, and the information flow is convenient. If you want to know the price, you can search on the Internet. There are many platforms for trading chemical products, or there are such things, and the price is also clearly listed on them. However, the price of each platform may be high or low, and it needs to be carefully screened. Or ask the distributors of chemical products, who are familiar with the market conditions and can tell you a more accurate price.
However, the market price changes rapidly, and it is difficult to give you an exact number. Only by looking for it in person can you get the current actual price. If you are in a hurry to know, in my opinion, you can quickly look for it on the Internet or call the dealer, and you will get it.

5-Bromo-1H-imidazolo [4,5-b] pyridine is an important organic compound that is commonly used in chemical experiments and industrial production. Regarding its safety precautions, it is necessary to be cautious.
First, this substance is toxic and may cause damage to the human body after contact. Be sure to wear suitable protective equipment when operating, such as protective gloves, goggles and gas masks, to prevent skin contact, eye splashing and inhalation of dust or volatile gases. In case of inadvertent contact, rinse with plenty of water immediately and seek medical attention in time.
Second, this compound is flammable. Keep away from fire sources and high temperature objects for storage and use to avoid fire. At the same time, the storage environment should be kept cool, dry and well ventilated to prevent its volatilization and accumulation, reducing the risk of fire and explosion.
Third, when conducting chemical reactions involving this compound, it is necessary to precisely control the reaction conditions, such as temperature, pressure and ratio of reactants. Improper reaction conditions or cause the reaction to go out of control, causing danger. In addition, the experimental operation should be carried out in the fume hood, and the harmful gases generated by the reaction should be discharged in time.
Fourth, after use, the waste must be properly disposed of. It should not be discarded at will. It should be classified into a specific chemical waste container according to relevant regulations and disposed of by a professional organization to prevent environmental pollution.
In conclusion, when handling 5-bromo-1H-imidazolo [4,5-b] pyridine, it is necessary to strictly follow safety operating procedures and exercise caution to ensure personal safety and environmental safety.