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What is the chemical structure of 1-Phenyl-4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c] pyridine?
The chemical structure of 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine can be deduced as follows. "1-phenyl" means that in the molecular structure, there is a phenyl group attached to the main structure. The phenyl group is the remaining group after the benzene ring is removed from a hydrogen atom. It has a cyclic structure composed of six carbon atoms and has a conjugated double bond on the ring, which is stable and aromatic.
The term "4,5,6,7-tetrahydro" means that on the carbon atoms at positions 4, 5, 6, and 7 of the main structure, the original double bond is converted into a single bond by hydrogenation reaction, and hydrogen atoms are added. This change results in a decrease in the degree of unsaturation of the main structure.
"1H-pyrazolo [4,3-c] pyridine" part, the structure of pyrazolo-pyridine is formed by fusing the pyrazole ring with the pyridine ring. Pyrazole ring is a five-membered heterocycle containing two adjacent nitrogen atoms, which has certain aromatic properties. Pyridine ring is a six-membered heterocycle containing one nitrogen atom, which is also aromatic. The way of fusing the two is [4,3-c], that is, according to the specific atomic connection rules, the pyrazole ring and the pyridine ring combine to form a unique fused ring structure. 1H represents the hydrogen atom in the first position. This hydrogen atom occupies a specific position in the whole molecular structure, which affects the chemical properties and reactivity of the molecule.
In summary, the chemical structure of 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine is a complex organic compound with a pyrazolo-pyridine fused ring as the backbone, 4, 5, 6, and 7 positions are hydrogenated, and 1 position is connected with a hydrogen atom, and at a specific position is connected with a phenyl group.
What are the main physical properties of 1-Phenyl-4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c] pyridine?
1-Phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine, which is an organic compound. Its main physical properties are as follows:
Looking at its properties, it is mostly solid at room temperature and pressure, but the specific form may vary depending on the purity and crystallization conditions, or it is crystalline or powdery.
When it comes to the melting point, due to the presence of aromatic rings and heterocyclic rings in the molecular structure, the melting point is relatively high due to the mutual force. However, the exact value varies slightly due to different literature reports, and is roughly within a certain temperature range.
In terms of boiling point, in view of the existence of various forces between molecules, such as van der Waals forces, hydrogen bonds, etc., its boiling point is also at a high level to overcome the intermolecular forces and achieve gas-liquid conversion.
In terms of solubility, the compound has relatively good solubility in organic solvents, such as ethanol, dichloromethane, acetone, etc. Due to the fact that the aromatic ring and heterocyclic structure in the molecule are similar to the organic solvent molecules, they can be uniformly dispersed in the solvent through the interaction of van der Waals forces. In water, its solubility is poor, because the overall polarity of the molecule is limited, and it is difficult to form an effective interaction with water molecules.
In addition, the density of the compound is moderate, slightly higher than that of water. The molecular structure endows it with certain stability, and it is not easy to decompose and other reactions under conventional conditions. However, when encountering special conditions such as high temperature and strong oxidizing agent, its structure may change.
1-Phenyl-4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c] pyridine in which applications?
1-Phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine is useful in various fields such as medicine and materials.
In the field of medicine, it has attracted much attention. Gai can be used as a lead compound for drug development because of its unique structure and potential biological activity. Studies have found that it may have an affinity for related targets of specific diseases, such as in neurological diseases, or can regulate neurotransmitter transmission, and has potential value in the treatment of epilepsy, Parkinson's disease, etc.; in anti-tumor research, it may also inhibit tumor cell proliferation and induce apoptosis, providing new ideas for the creation of anti-cancer drugs. < Br >
In the field of materials, it also shows its promise. Due to its special molecular structure, it can give materials different properties. In optical materials, it can improve the luminescence properties of materials, so that materials can be used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) to improve display effects; in polymer materials, adding this substance may enhance the mechanical properties of materials, such as improving the strength and toughness of plastics, and broadening its application range.
Furthermore, in the field of organic synthesis, it can be used as a key intermediate. With its structural characteristics, it can use a variety of chemical reactions to construct complex organic molecular structures, facilitate the synthesis of new compounds, enrich the library of organic compounds, and lay the foundation for the development of more fields. In conclusion, 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine has important application and development potential in many fields.
What are the synthesis methods of 1-Phenyl-4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c] pyridine?
The synthesis of 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine is an important matter in the field of organic synthetic chemistry. The synthesis of this compound often depends on several ways.
One of them can be constructed by nitrogen-containing heterocycles. First, take a suitable pyridine derivative and introduce a pyrazole structure on the pyridine ring through a specific reaction. For example, take pyridine as the starting material and react it with hydrazine compounds under appropriate conditions, or obtain an intermediate containing a pyrazolo-pyridine skeleton. The reaction conditions are very critical, such as temperature, pH, reaction time, etc. All need to be carefully regulated. Usually, in an organic solvent, under the action of heating and catalyst, the nucleophilic substitution or cyclization reaction can occur between the two, and then the core structure of pyrazolopyridine can be constructed.
Second, it can be started from the phenyl starting material. Select suitable phenyl halide or other active phenyl derivatives to react with reagents with the potential structure of pyridine and pyrazole. In the meantime, it may involve metal-catalyzed coupling reactions, such as palladium-catalyzed reactions. In such reactions, palladium catalysts can promote the connection of phenyl groups to pyridine-pyrazole structural units. At the same time, the choice of ligands is also very important, which can affect the activity and selectivity of the reaction. The combination of ligands and palladium catalysts can regulate the reaction process and ensure that the reaction proceeds in the direction of
Furthermore, the strategy of intramolecular cyclization can also be used. The structure of the target compound is constructed by molecular closed-ring reaction using chain-like precursors containing specific functional groups as raw materials. Such reactions require clever design of the structure of the precursor molecule, so that the functional groups interact under specific conditions and cyclize. For example, the reaction between unsaturated bonds such as alkenyne and nitrogen-containing functional groups is used to form a pyrazole-pyridine ring system through intramolecular cyclization. During the reaction, the cyclization reaction can be triggered by conditions such as light, heat or free radical initiators to realize the transition from chain-like structure to cyclic structure.
All synthetic methods have their own advantages and disadvantages. In actual operation, it is necessary to comprehensively consider the availability of raw materials, the difficulty of controlling the reaction conditions, the yield and purity of the target product, and make a careful choice. The purpose of synthesizing 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine can be achieved.
What is the market outlook for 1-Phenyl-4,5,6, 7-tetrahydro-1H-pyrazolo [4,3-c] pyridine?
Today, there are 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine, and its market prospects are related to many aspects. Looking at the current field of pharmaceutical and chemical industry, this compound has great potential.
In the process of drug development, many studies have shown that those with such structures may have unique biological activities. It can be used as a lead compound to help create new drugs. Because drug development often requires novel structures to find effective and low-toxicity prescriptions. This compound has a specific structure and may interact with specific biological targets, which holds great potential for development in the fields of anti-cancer, anti-inflammatory, and neurological drug development.
In chemical materials, it may be used as a key intermediate for the synthesis of new materials. With the advance of materials science, the demand for special structural compounds is increasing. The structure of 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine may endow the material with unique properties, such as optical and electrical properties, etc., and it is expected to emerge in the fields of electronic materials and polymer materials.
However, its market prospects are not smooth sailing. If the process of synthesizing this compound is complicated and expensive, it will be unfavorable for large-scale production. Researchers need to study and optimize, reduce costs and increase efficiency. And the market competition is fierce, and similar or alternative compounds also exist. In order to dominate the market, we must highlight our unique advantages.
In summary, the market for 1-phenyl-4,5,6,7-tetrahydro-1H-pyrazolo [4,3-c] pyridine has a bright future, but challenges also exist. Only when scientific research and industry work together to overcome problems can we tap its maximum potential and bloom in the market.