1-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[3,4-b]pyridine

1 - methyl - 5 - (4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan - 2 - yl) pyrazolo [3,4 - b] pyridine, an organic compound. Its chemical structure is quite complex, which is composed of several parts cleverly combined.
Looking at its structure, the first thing to see is "pyrazolo [3,4 - b] pyridine", which is the structure of pyrazolo [3,4 - b] pyridine. Pyrazolo-pyridine compounds have a unique cyclic structure and are often found in many fields of medicinal chemistry and organic synthesis. The pyridine ring is a six-membered nitrogen-containing heterocycle with aromatic properties, and the pyrazole ring is fused to it. The interaction between the two makes the overall structural stability and electronic properties unique.
"1-methyl" is clearly shown in the first position of the pyrazolo [3,4-b] pyridine structure, which is connected with a methyl group. The introduction of methyl groups alters the steric resistance and electron cloud distribution of the molecule, which affects the physicochemical properties of the compound, such as boiling point, solubility and reactivity.
Furthermore, "5 - (4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan - 2 - yl) " indicates that at the 5th position of pyrazolo [3,4 - b] pyridine, a 4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan ring - 2 - group is connected. This boronyl ester group is widely used in organic synthesis and often participates in various reactions as a nucleophile, such as the Suzuki coupling reaction. In its structure, boron atoms form a stable five-membered ring with two oxygen atoms, and there are four methyl groups attached to the ring, which enhance the stability of the group and the steric resistance effect.
In summary, 1-methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) pyrazolo [3,4-b] pyridine is composed of pyrazolo [3,4-b] pyridine as the parent nucleus, and 1-methyl and 5-tetramethyl-1,3,2-dioxoboramyl-2-yl are modified. Each part works synergistically to endow the compound with unique chemical properties and reactivity.

1 - methyl - 5 - (4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan - 2 - yl) pyrazolo [3,4 - b] pyridine, which is a key organoboron compound in the field of organic synthesis. It has a wide range of uses and mainly covers the following aspects:
First, in the field of medicinal chemistry, it is often used as a key intermediate. In the process of creating new drug molecules, with its unique chemical properties, it can precisely construct complex molecular structures with specific biological activities through the formation and transformation of boron-carbon bonds. For example, in the research and development of some anti-cancer drugs, this compound can be used as a key building block to precisely build a molecular skeleton with specific anti-cancer activity by palladium-catalyzed coupling reaction with other halogenated compounds, providing an important material basis for the creation of new drugs.
Second, in the field of materials science, it also plays an important role. It can participate in the preparation of functional organic materials, such as organic Light Emitting Diode (OLED) materials. With the help of the structural modifiability of this compound, it can be introduced into the organic conjugate system by rationally designing the reaction path, thereby improving the electron transport performance and luminous efficiency of the material, and improving the performance of OLED devices.
Third, in the field of organic synthetic chemistry, it is an extremely important synthesizer. It can participate in many types of coupling reactions, such as Suzuki-Miyaura coupling reactions. In such reactions, it can react with aryl halides, alkenyl halides, etc. under the action of suitable catalysts and bases, and efficiently form carbon-carbon bonds. It provides an extremely effective strategy for the synthesis of various organic compounds with specific structures and functions, and is widely used in the total synthesis of natural products, the construction of new organic functional molecules, and many other aspects.
To sum up, 1-methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) pyrazolo [3,4-b] pyridine, with its diverse and unique chemical properties, has shown crucial value in many fields such as drug development, material preparation, and organic synthesis, promoting continuous development and innovation in related fields.

The synthesis of 1-methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxoborocyclopentane-2-yl) pyrazolo [3,4-b] pyridine is quite complicated and requires many steps to obtain this compound.
At the beginning, pyrazolo [3,4-b] pyridine derivatives are often used as binders. A specific substituent is introduced at the appropriate check point of this derivative to lay the foundation for subsequent reactions with boron reagents. This substitution reaction requires careful selection of reaction conditions, such as temperature, solvent, and catalyst type and dosage, which all have a significant impact on the reaction process and product purity.
Next, the step of introducing boron groups is generally to use boron-containing reagents, such as tetramethyl-1,3,2-dioxoboronheterocyclopentane-related reagents. This reaction needs to be carried out in a suitable alkaline environment, and the strength of alkalinity needs to be precisely controlled. Too strong or too weak is not conducive to the advancement of the reaction towards the direction of generating the target product. In this process, the efficacy of the catalyst cannot be ignored, which can effectively improve the reaction rate and promote the smooth integration of boron groups into the predetermined position.
After the reaction is completed, the product needs to go through multiple purification steps, such as column chromatography. This is to take advantage of the difference in the distribution coefficient between the stationary phase and the mobile phase of different compounds to achieve the purpose of separation and purification. Pure 1-methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxyboron heterocyclopentane-2-yl) pyrazolo [3,4-b] pyridine can be obtained by layer-by-layer purification and removal of impurities. Each step requires fine operation, and a slight poor pool may affect the quality and yield of the product.

1 - methyl - 5 - (4,4,5,5 - tetramethyl - 1,3,2 - dioxaborolan - 2 - yl) pyrazolo [3,4 - b] pyridine is an organic compound, and its physicochemical properties are quite important, which is related to its application in many fields.
Looking at its physical properties, under normal temperature and pressure, the state of this compound is particularly critical. However, the literature does not specify whether it is in a solid state, a liquid state or a gaseous state. However, due to the many aromatic rings and boroxyl heterocycles contained in its structure, it can be deduced to be a solid state. The structure of the aromatic ring often enhances the intermolecular force and tends to form a solid state. Its melting point and boiling point are also key physical parameters, and exact data are rarely available. However, according to the structure, due to the potential of hydrogen bond receptor and donor in the molecule, coupled with the conjugated system of aromatic rings, it may have a high melting point and boiling point.
As for the chemical properties, the structure of pyrazolopyridine in this compound endows it with unique reactivity. Pyrazolopyridine rings are rich in electrons and are prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. Under appropriate conditions, the hydrogen atoms on the ring can be attacked by electrophilic reagents to generate corresponding substitution products. The boron ester group, namely 4,4,5,5-tetramethyl-1,3,2-dioxoboro-heterocyclopentane-2-yl, brings it a variety of chemical properties. This boron ester can participate in many organic synthesis reactions, such as Suzuki-Miyaura coupling reaction. In the presence of alkali and palladium catalyst, it can couple with halogenated aromatics or olefins to form carbon-carbon bonds, which is widely used in drug synthesis and materials science. In addition, boron ester groups are sensitive to air and moisture, and attention should be paid to isolating air and moisture during storage and use to prevent side reactions such as hydrolysis, which affect their chemical stability and reactivity.

I do not know the price range of "1-methyl-5- (4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl) pyrazolo [3,4-b] pyridine" in the market. This compound may be used in scientific research in a specific field, and its price is determined by many factors, such as purity, yield, market supply and demand, and the quotations of each supplier are also different.
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