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What is the chemical structure of 1-methyl-3-hydroxypyridine-2-one?
1-methyl-3-hydroxypyridine-2-one is an organic compound, and its chemical structure can be summarized as follows.
This compound uses pyridine as the parent nucleus, and pyridine is also a nitrogen-containing hexa-ring compound. It has aromatic properties. In the first position of the pyridine ring, there is one methyl group (-CH 🥰), and the methyl group is an alkyl group composed of carbon and hydrogen, which is a common substituent for organic compounds. In the third position of the pyridine ring, there is a hydroxy group (-OH), which has active chemical properties and can participate in many chemical reactions, such as esterification and oxidation. Furthermore, in the second position of the pyridine ring, it is a carbonyl group (C = O), and the carbonyl group is a polar functional group, which makes the compound have certain reactivity and physical properties, and affects the electron cloud distribution and spatial structure of the molecule.
Overall, the chemical structure of 1-methyl-3-hydroxypyridine-2-one is based on the pyridine ring and is composed of functional groups such as methyl, hydroxyl and carbonyl. This unique structure endows the compound with specific chemical and physical properties, and may have important applications and research value in organic synthesis, medicinal chemistry and other fields.
What are the main uses of 1-methyl-3-hydroxypyridine-2-one?
1-Methyl-3-hydroxypyridine-2-one, which is 1-methyl-3-hydroxypyridine-2-one, has a wide range of uses and has its impact in many fields.
First, in the field of medicine, its role cannot be underestimated. It can be used as a key intermediate in drug synthesis. Due to its specific chemical structure, it can participate in the construction of many drug molecules, helping to develop new drugs with unique therapeutic effects. For example, in the synthesis path of some antibacterial drugs, 1-methyl-3-hydroxypyridine-2-ketone can be ingeniously integrated into the drug molecular structure through a series of chemical reactions, giving the drug more excellent antibacterial activity, or improving the metabolic properties of the drug in the body and enhancing the efficacy of the drug.
Second, in the field of materials science, it also shows unique value. It can be used to prepare materials with special properties. For example, introducing it into polymer materials can change the physical and chemical properties of the material. For example, by enhancing the stability of the material, it can better maintain its own structure and properties under different environmental conditions; or by adjusting the optical properties of the material, giving the material unique optical properties, which has potential applications in optoelectronic devices.
Third, it also makes contributions in the field of agriculture. It can be used as an important raw material for pesticide synthesis. With its chemical properties, pesticides can be synthesized that have an efficient control effect on crop diseases and insect pests. Such pesticides may have more precise targets, and have stronger ability to inhibit or kill target diseases and insects. At the same time, the impact on the environment and non-target organisms is relatively small, which is in line with the needs of modern green agriculture development.
Fourth, in the field of organic synthetic chemistry, it is an extremely important building block for organic synthesis. Organic chemists can modify and derive organic compounds with complex and diverse structures through various organic reactions, which greatly expands the scope and possibility of organic synthesis and provides rich materials and tools for organic chemistry research.
What are the physical properties of 1-methyl-3-hydroxypyridine-2-one?
1-Methyl-3-hydroxypyridine-2-one is one of the organic compounds. Its physical properties are worth exploring.
Looking at its appearance, it often appears solid at room temperature. The color is either nearly colorless or white, with a fine texture and a powder-like shape. It is clean and uniform when viewed by the eye.
The melting point is about a specific temperature range. This temperature is the key node for a substance to change from a solid state to a liquid state. Due to the characteristics of intermolecular forces, its melting point is fixed, which is an important basis for identifying and purifying the substance.
As for the boiling point, it also has a corresponding value. When the temperature rises to the boiling point, the substance is liquefied from the liquid state to the gaseous state. During this process, the kinetic energy of the molecule is sufficient to overcome the attractive force between the molecules, so that the liquid phase can escape. The determination of boiling point is of great significance for the separation and identification of substances.
In terms of solubility, 1-methyl-3-hydroxypyridine-2-one exhibits different solubility characteristics in specific solvents. In some organic solvents, such as ethanol and acetone, it can be better dissolved. Due to the existence of suitable interactions between the molecular structure and the solvent molecules, such as hydrogen bonds, van der Waals forces, etc., the solute molecules are uniformly dispersed in the solvent. In water, its solubility may be limited due to the degree of matching between the polarity of the molecule and the water molecule.
Density is also one of its physical properties. This value reflects the mass per unit volume of a substance and is related to the size and close arrangement of the molecules. Accurate determination of density helps to understand its distribution in the mixture and the possibility of separation from other substances.
In addition, the volatility of this compound is weak. Due to its relatively strong intermolecular forces, molecules are not easy to break away from the solid or liquid surface and enter the gas phase. Therefore, under normal temperature and pressure, the volatilization rate is slow. This property also affects its stability and durability in the environment.
From the above, it can be seen that the physical properties of 1-methyl-3-hydroxypyridine-2-one have their own characteristics and significance, and are indispensable factors in many fields such as chemical research and industrial applications.
What are 1-methyl-3-hydroxypyridine-2-one synthesis methods?
1-methyl-3-hydroxypyridine-2-one is an organic compound. There are many synthesis methods, and now I will describe several common ones in detail.
First, it can be prepared by the oxidation and substitution reaction of pyridine compounds. First, take a suitable pyridine derivative and oxidize it with a specific oxidant, such as peroxide, to introduce hydroxyl groups at a specific position on the pyridine ring. Then, methylation is carried out with methylating reagents, such as iodomethane and base, and methyl groups are introduced at the appropriate position. After careful separation and purification steps, 1-methyl-3-hydroxypyridine-2-one can be obtained.
Second, it can also be achieved by a nitrogen-containing heterocyclic construction strategy. Using small molecules with suitable functional groups as starting materials, pyridine rings are constructed through multi-step reactions. For example, using β-dicarbonyl compounds and nitrogen-containing reagents, under the catalysis of acids or bases, through a series of reactions such as condensation and cyclization, the pyridine ring structure is first constructed. Later, for specific positions on the ring, hydroxylation and methylation are used to introduce hydroxyl groups and methyl groups in turn, and the final product is obtained. In this process, the reaction conditions of each step need to be precisely controlled, such as reaction temperature, time, and reagent dosage, which all have a significant impact on the reaction yield and selectivity.
Third, the idea of biosynthesis can also be used. Using the catalytic properties of certain microorganisms or enzymes, the synthesis of 1-methyl-3-hydroxypyridine-2-one is achieved under mild conditions with specific substrates as raw materials. Although this method has the potential for green and high efficiency, it is very demanding for the screening and culture of biological systems. It is necessary to find microorganisms or enzymes that can specifically catalyze related reactions, and optimize the reaction conditions to improve the yield.
All the above synthetic methods have their own advantages and disadvantages. In practical application, the appropriate method needs to be weighed according to specific needs and conditions.
What is the price range of 1-methyl-3-hydroxypyridine-2-one in the market?
I think this "1-methyl-3-hydroxypyridine-2-one" is a chemical product. However, the price range on the market is difficult to determine. The price is affected by various factors, such as the quality of the product, the situation of supply and demand, the simplicity of production, the region of sale and the pricing strategy of the merchant.
If there were such chemicals in the ancient books of "Tiangong Kaiwu" in the past, or due to the limitations of skills and cognition at that time, the price was not detailed. However, in today's time, if the quality is ordinary, the demand is not extremely strong, and the production is easy, in the common chemical market, the price per gram may be between a few yuan and tens of yuan. If the quality is high, the demand is high, the production is complicated, or the special purpose is involved, the price can reach 100 yuan per gram or even higher. In different regions, the price varies due to differences in transportation costs and market competition.
In short, if you want to know the exact price range, you can get a more accurate number when you carefully check the chemical market information and consult the merchants.