1-Methyl-1,2-dihydro-2-oxopyridine-5-carboxylic acid methyl ester

Methyl 1-methyl-1,2-dihydro-2-oxo-pyridine-5-carboxylate is widely used. In the field of pharmaceutical synthesis, it is often a key intermediate. Due to its unique chemical structure, it can participate in many reactions, assisting medical chemists in constructing complex active molecular structures for the creation of new drugs for the treatment of various diseases, such as antibacterial, anti-inflammatory, anti-tumor and other drugs.
In the field of organic synthesis chemistry, it is also an important building block. Chemists can expand the structural diversity of organic compounds by modifying them, such as introducing different substituents on the pyridine ring, or performing reactions such as conversion of ester groups, providing rich raw materials for the exploration of new materials.
In addition, in the preparation of some fine chemicals, 1-methyl-1,2-dihydro-2-oxypyridine-5-carboxylic acid methyl esters also play an indispensable role in helping to improve the performance and quality of products, and are widely used in fragrance, dye and other industries to promote the development of the fine chemical industry.

1-Methyl-1,2-dihydro-2-oxo-pyridine-5-carboxylic acid methyl ester, this is an organic compound, its physical properties are quite important, and it is related to many chemical processes and applications.
Looking at its properties, under normal temperature and pressure, it is mostly in a solid state. Its specific form may be crystalline, the texture is relatively dense, and the appearance may have a certain luster. However, it is also affected by the preparation process and purity.
When it comes to the melting point, the melting point of this compound is a specific value, which is crucial when identifying and purifying. When heated to this temperature, the substance gradually melts from the solid state to the liquid state. This process requires the absorption of specific heat, and the exact value of its melting point can be determined due to the intermolecular forces and structure.
The boiling point is also a key physical property. Under a specific pressure, when the compound is heated to the boiling point, it is rapidly converted from the liquid state to the gaseous state. The boiling point of methyl 1-methyl-1,2-dihydro-2-oxo-pyridine-5-carboxylate reflects the difficulty of its gasification, which is of great significance for separation and purification methods such as distillation.
In terms of solubility, it varies in different solvents. In organic solvents, such as common ethanol, acetone, etc., or have a certain solubility. Due to the principle of similar dissolution, its organic structure is compatible with the intermolecular forces of organic solvents, and it can be better dispersed. However, in water, due to the polarity difference between its structure and water, its solubility or poor solubility, only a small amount is soluble.
Density is also an important physical parameter. The density of this compound reflects the size of the mass per unit volume. When mixed with other substances, the density affects its delamination and other behaviors. In chemical production and experimental operations, it is of guiding significance for material ratio and separation operations.
In addition, its refractive index also has specific values. The refractive index is related to the molecular structure of the substance and the distribution of electron clouds. It can be used for purity detection and substance identification. When light passes through this compound, the degree of propagation direction change is reflected by the refractive index.
The physical properties of this compound are interrelated and play an important role in many fields such as chemical synthesis, analytical testing, and drug development. Only by understanding and mastering its physical properties can we better control and utilize this compound.

The synthesis of 1-methyl-1,2-dihydro-2-oxo-pyridine-5-carboxylic acid methyl ester is a subject of great concern in the field of chemistry. To synthesize this substance, it can be achieved through many ways.
First, the methyl group can be introduced into the specific position of the pyridine ring by starting with the pyridine derivative. This process can be selected by using a suitable methylating agent, such as iodomethane, under appropriate base and reaction conditions, to promote the smooth integration of the methyl group. Then, the pyridine ring is modified by dihydro and carbonylation, or by using specific reducing reagents and oxidizing reagents, and the structure of the dihydro-2-oxo is achieved step by step. Finally, the corresponding carboxylic acid and methanol are used to form the desired carboxylic acid methyl ester through esterification reaction under the action of catalyst.
Second, the pyridine ring can also be constructed by cyclization from other nitrogen-containing heterocyclic compounds. During the cyclization process, the reaction conditions and raw materials are cleverly designed to introduce the structural units of methyl, dihydro-2-oxo and methyl carboxylate synchronously or step by step. This approach requires precise control of the mechanism and conditions of the cyclization reaction to ensure that the reaction proceeds in the expected direction.
In addition, the strategy of inverse synthesis analysis can also be considered to disassemble the target product into several easy-to-obtain simple fragments, and then synthesize these fragments one by one, and then combine them into the final product through splicing reaction. This strategy requires in-depth understanding of the selectivity and compatibility of various organic reactions in order to efficiently achieve the synthesis of target molecules.
There are many methods for synthesizing 1-methyl-1,2-dihydro-2-oxypyridine-5-carboxylate methyl esters, but all of them require fine regulation of reaction conditions, careful selection of raw materials and reagents, in order to achieve high yield and high purity synthesis goals.

I think what you are asking is about the price range of 1 - Methyl - 1,2 - dihydro - 2 - oxopyridine - 5 - carboxylic acid methyl ester in the market. However, this is not an easy matter, and its price often changes due to many factors.
First, the price of raw materials is the key. If the raw materials for preparing this compound are rare or expensive, the price of this compound will also rise. Second, the complexity of the production process has a great impact. If a fine and difficult process is required, it will consume a lot of manpower and material resources, and the price will be high. Third, the state of market supply and demand also affects the price. If demand is strong and supply is scarce, the price will rise; conversely, if supply exceeds demand, the price will fall.
According to past transactions and market conditions, the price of this compound fluctuates widely. In the case of ordinary purity and small batches, the price per gram may be between tens and hundreds of yuan. If the purity is extremely high, it reaches the scientific research level, or the batch is very large, the price will be different. When the batch is large, the unit price may be reduced to a lower level due to the scale effect; for high-purity scientific research products, the price per gram may exceed 100 yuan, or even hundreds of yuan. < Br >
However, this is only a rough guess. To know the exact price, you should consult the chemical product supplier in detail, or explore the latest quotation on the relevant chemical trading platform.

1-Methyl-1,2-dihydro-2-oxo-pyridine-5-carboxylic acid methyl ester, this is an organic compound. During storage and transportation, many matters need to be paid attention to.
First of all, storage should be placed in a cool, dry and well-ventilated place due to its nature. If the environment is humid, or the compound is damaged by moisture, it will affect its quality and performance. Temperature also needs to be strictly controlled. Excessive temperature may cause chemical reactions, causing it to decompose or produce other adverse changes. At the same time, it must be stored separately from oxidants, acids, bases and other substances. Due to its chemical activity, contact with these substances may cause violent reactions, and even risk combustion and explosion.
As for transportation, the packaging must be solid and firm to ensure that it will not be damaged and leaked during transportation. The transportation process needs to follow relevant regulations and standards, and the transportation vehicle should be equipped with corresponding fire protection equipment and leakage emergency treatment equipment. During transportation, it should be protected from exposure to the sun, rain and high temperature. When loading and unloading, it should be handled lightly to avoid packaging damage due to rough operation and cause safety accidents.
In short, the storage and transportation of 1-methyl-1,2-dihydro-2-oxo-pyridine-5-carboxylate methyl ester requires caution and strict follow-up to ensure the safety of personnel and the environment, and at the same time ensure that the quality of the compound is not damaged.