1 Hydroxy 2 1h Pyridinethion Sodium Salt
pyridine pyrrole pyrazine piperidine piperazine

1-hydroxy-2-(1h)-pyridinethion sodium salt

    Specifications

    HS Code

    679909

    Chemical Formula C5H4NOSNa
    Molecular Weight 149.14 g/mol
    Appearance Yellow to greenish - yellow solid
    Odor Characteristic, faint odor
    Solubility In Water Soluble
    Solubility In Organic Solvents Soluble in polar organic solvents like ethanol
    Ph Range 9 - 11 in aqueous solution
    Melting Point 122 - 125 °C
    Antimicrobial Property Effective against bacteria, fungi, and yeasts
    Stability Stable under normal conditions, but may decompose on exposure to strong acids or bases

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    General Information
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    Frequently Asked Questions

    As a leading 1-hydroxy-2-(1h)-pyridinethion sodium salt supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1-hydroxy-2- (1h) -pyridinethion sodium salt?
    1 - hydroxy - 2 - (1H) - pyridinethion sodium salt is sodium hydroxymethylpyridine, commonly known as omedine sodium. Its main uses are as follows:
    In the field of daily chemical industry, it is often the key ingredient of cosmetics and personal care products. This is because it has excellent antibacterial and antifungal effects, which can effectively resist microorganisms such as Malassezia. In shampoo products, it can inhibit the growth of microorganisms in the scalp, relieve scalp itching and desquamation, return hair and scalp to health, and achieve the effect of anti-dandruff and anti-itching. In skin care products, it can prevent and control skin problems caused by microorganisms, maintain the balance of skin flora, and make the skin healthier and smoother.
    In the field of medicine, it also shows important functions. Due to its antibacterial properties, it can be applied to external preparations to assist in the treatment of skin diseases caused by fungi or bacteria, help relieve symptoms and promote skin healing.
    In the industrial field, in paints, plastics and other products, it can act as a preservative. By inhibiting the growth of microorganisms, prolong the service life of products, prevent product deterioration and damage caused by microbial erosion, and ensure the stability of product quality and performance.
    It can be seen that 1-hydroxy-2 - (1H) -pyridinethion sodium salt plays an important role in many fields. With its antibacterial and antifungal properties, it provides many benefits for people's lives and industrial production.
    What is the safety of 1-hydroxy-2- (1h) -pyridinethion sodium salt?
    1 - hydroxy - 2 - (1h) - pyridinethion sodium salt, that is, hydroxymethopyridone sodium salt, is often referred to by its trade name, such as omedine sodium. The safety of this substance is of great concern, as detailed below:
    From the perspective of toxicity, after many experiments, its acute toxicity is quite low at the conventional use dose. The oral half lethal dose (LD50) value of rats is quite high, which indicates that a large amount of intake of prescription may cause serious acute toxicity. Daily use rarely reaches this dose. However, if overdose is taken incorrectly, it may cause gastrointestinal discomfort, such as nausea, vomiting, and abdominal pain.
    At the level of skin contact, generally speaking, normal skin contact with substances containing this ingredient rarely causes allergies or irritation. Among the many skin care products and shampoos contained in it, most people have not experienced adverse skin reactions after population trial and monitoring. However, some people with sensitive skin may be at risk of contact dermatitis, causing skin redness, swelling and itching. Therefore, before using new products, people with sensitive skin should have a local skin test.
    Re-discuss the risk of inhalation. In normal product use scenarios, such as shampooing and skin care, there will rarely be inhalation. However, in the production environment, if the dust protection is insufficient, workers will inhale dust containing this ingredient for a long time, or cause irritation to the respiratory tract, causing symptoms such as cough and asthma. It is necessary to have good ventilation and dust control measures in the production site.
    In terms of environmental safety, some of this substance can be decomposed by natural degradation process after entering the environment. However, a large amount of discharge may still have a potential impact on the water ecology. Studies have shown that under high concentrations, the growth and reproduction of aquatic organisms such as fish and algae may be inhibited, so the production and use process should pay attention to reasonable discharge to avoid excessive pressure on the environment.
    In summary, 1-hydroxy-2 - (1h) - pyridinethion sodium salt is safe under normal and reasonable use, but the use and production process need to pay attention to the risks in specific scenarios to ensure the safety of human beings and the environment.
    1-Hydroxy-2- (1h) -pyridinethion sodium salt is common in which products
    Sodium 1-hydroxy-2- (1H) -pyrithione, also known as sodium pyrithionium, is common in many products in the fields of daily chemicals, medicine, agriculture, etc.
    In the category of daily chemicals, it can often be found in shampoo and hair care products. Because of its excellent antibacterial and antifungal properties, it can effectively inhibit the growth of microorganisms such as Malassezia. Overreproduction of Malassezia can easily cause dandruff. This ingredient can create an environment that is not conducive to its survival and reduce scalp itching and dandruff problems. For example, many well-known anti-dandruff shampoos use it as a key active ingredient. Body wash is also commonly used to resist bacteria and fungi on the surface of the skin, keep the skin healthy and clean, and prevent skin discomfort caused by the growth of microorganisms.
    In the field of medicine, some external dermatological ointments and lotions contain this ingredient. For some skin diseases caused by fungi or bacteria, such as tinea corporis and tinea corporis, its antibacterial properties can help relieve symptoms and promote skin recovery. For example, some over-the-counter ointments for treating skin inflammation and infection, add this ingredient to enhance the efficacy.
    In agriculture, some fungicides contain 1-hydroxy-2- (1H) -pyrithione sodium. It can be used in crops to prevent the invasion of fungal diseases, ensure the healthy growth of crops, and improve the yield and quality of agricultural products. In the cultivation of fruits and vegetables, it can reduce post-harvest rot and prolong the shelf life.
    What is the mechanism of action of 1-hydroxy-2- (1h) -pyridinethion sodium salt
    1 - hydroxy - 2 - (1H) - pyridinethion sodium salt is sodium hydroxymethylpyrithione, often referred to as OCT. Its mechanism of action is as follows:
    The reason why OCT can play a role is because of its unique chemical structure and properties. This substance can bind to specific receptors on the surface of microbial cell membranes, which is a key step in the initiation of its role. Once bound, it is like a key inserted into a keyhole, disrupting the normal physiological function of the cell membrane. Cell membranes are crucial to microorganisms, just like the city walls, controlling the entry and exit of substances and the stability of the intracellular environment.
    The intervention of OCT changes the permeability of the cell membrane, just like a hole in the city wall. Key components that should have been left in the cell, such as proteins, nucleic acids, etc., begin to flow out, while harmful or should not be outside the cell take advantage of it. At the same time, OCT can also interfere with the activities of many key enzymes in microbial cells. Enzymes are like craftsmen in the cell, catalyzing various important biochemical reactions. OCT changes the activity of enzymes, causing many biochemical reactions closely related to the growth and reproduction of microorganisms to fail to proceed normally, such as energy metabolism, DNA replication, etc. As a result, the growth and reproduction process of microorganisms is hindered, and even leads to death. In practical applications, OCT is often used in antibacterial and antiseptic fields by virtue of this mechanism of action. For example, in personal care products, it can effectively inhibit the growth of bacteria and fungi, ensuring product quality and user health.
    What are the side effects of 1-hydroxy-2- (1h) -pyridinethion sodium salt
    1-Hydroxy-2- (1H) -pyrithione sodium salt solution, also known as pyrithionium sodium, is a common chemical raw material and has applications in many fields. However, it also has some potential side effects, which need to be paid attention to.
    In personal care products, such as shampoos and body washes, this substance is often used as a preservative and antibacterial agent, which can effectively resist the growth of bacteria and fungi, maintain product stability, and prevent scalp itching, dandruff and other problems. However, some individuals may be allergic to it, and after use, it may cause contact dermatitis, symptoms include skin redness, itching, tingling, etc. < Br >
    In the industrial field, it is often used in coatings, paints, adhesives and other products to prevent microbial erosion and prolong the service life of the product. However, in the process of production and use, if the protection is improper, the substance may enter the human body through the respiratory tract and skin, irritating the respiratory tract and skin. Long-term exposure, or cause chronic damage to the respiratory system and skin.
    In terms of water treatment, 1-hydroxy-2- (1H) -pyrithione sodium salt solution can be used as a bactericidal algaecide to control the growth of microorganisms in water. However, excessive use or improper treatment may affect the ecological balance of water bodies, produce toxic effects on aquatic organisms, and interfere with the normal ecological functions of water bodies.
    In summary, although 1-hydroxy-2- (1H) -pyrithione sodium salt solution plays an important role in various industries, its potential side effects should not be underestimated. Be sure to follow relevant norms and standards when using it, and take appropriate protective measures to reduce its potential harm to human body and the environment.