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What is the chemical structure of 2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarboxamide?
1 - ethyl - 1,2 - dihydro - 6 - hydroxy - 4 - methyl - 2 - oxo - 3 - pyridinecarboxamide, this is the name of an organic compound. Looking at its name, according to the convention of organic chemical nomenclature, its chemical structure can be deduced.
"1 - ethyl", epiethyl is connected to the first position of the pyridine ring. "1,2 - dihydro", shows that the 1 and 2 positions of the pyridine ring are double-bonded hydrogenated to form a single bond. "6 - hydroxy", refers to the 6 position is connected with a hydroxyl group. "4 - methyl", shows that the 4 positions are connected with a methyl group. " "3-Pyridinecarboxamide", that is, the 3-position of the pyridine ring is connected with a formamide group.
To sum up, the chemical structure of this compound is based on the pyridine ring as the core, with ethyl at 1, carbonyl at 2, methyl at 4, hydroxyl at 6, formamide at 3, and single bonds between 1 and 2 positions. The structure can be briefly depicted as follows: first draw a pyridine ring, connected at 1 position to - CH ² CH, 2 positions to = O, 3 positions to - CONH ², 4 positions to - CH < unk >, 6 positions to - OH, 1 and 2 positions are connected by a single bond.
What are the main uses of 1-ethyl-1, 2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarboxamide?
1 - ethyl - 1,2 - dihydro - 6 - hydroxy - 4 - methyl - 2 - oxo - 3 - pyridinecarboxamide is an organic compound with a wide range of uses.
In the field of medicine, it may be a key pharmaceutical intermediate. Pharmaceutical intermediates are important starting materials or intermediates for the synthesis of various drugs. With the special structure of this compound, specific groups can be added or changed through a series of chemical reactions to construct pharmaceutical molecules with specific pharmacological activities. For example, for some inflammatory diseases, anti-inflammatory drugs can be developed on this basis; for specific nervous system diseases, its structure can be modified, or drugs with neuroprotective effects can be synthesized.
In the chemical industry, it can be used as an important raw material for organic synthesis. It can participate in many organic reactions and is used to prepare organic materials with different functions. For example, in the synthesis of polymer materials, structural fragments of this compound can be introduced to give the polymer material unique properties, such as improving the solubility, thermal stability or mechanical properties of the material. In the field of coatings, with its participation in the synthesis of polymers with special structures, coatings have better adhesion and corrosion resistance.
In addition, in agricultural chemistry, there may also be potential applications. It may be possible to develop new pesticides based on it, such as fungicides or herbicides. By modifying its chemical structure, it can effectively inhibit or kill specific crop diseases or weeds, and has a small impact on the environment, which is in line with the current needs of green agriculture development. In short, this compound has shown important value in many fields, providing a key foundation for the development and production of many products.
What are the physical properties of 2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarboxamide?
1 - ethyl - 1,2 - dihydro - 6 - hydroxy - 4 - methyl - 2 - oxo - 3 - pyridinecarboxamide, this is an organic compound. Its physical properties are as follows:
Look at its appearance, or it is a white to off-white crystalline powder with a fine texture. This is a common trait of many organic compounds, which is caused by the regular and orderly arrangement of molecules.
As for the melting point, or at a specific temperature range, this temperature is crucial to determine its purity and characteristics. When heated, the intermolecular forces gradually weaken, the lattice structure disintegrates, and then it changes from a solid state to a liquid state. The exact melting point can only be determined by professional instruments and repeated measurements.
Solubility is also an important property. In water, it may have a certain solubility, but because there are both hydrophilic hydroxyl groups and hydrophobic alkyl groups in the molecule, the solubility may be limited. In organic solvents, such as ethanol and acetone, the solubility may be different. Ethanol and the compound can form hydrogen bonds and other interactions, or increase their solubility; and the compatibility of the polarity of acetone with the molecular structure will also affect its solubility.
Its density is related to the mass of the unit volume. Although the exact value needs to be measured experimentally, it can be inferred according to its molecular composition and structural characteristics. The type, number and spatial arrangement of atoms in the molecule all affect the density.
In addition, the stability of the compound also needs to be considered. Under normal temperature and pressure, dark, dry environment, or relatively stable. However, under extreme conditions such as high temperature, strong acid, and strong base, the molecular structure may change, triggering chemical reactions and causing it to deteriorate.
The physical properties of this compound are of great significance to its synthesis, separation, purification, and application. By studying these properties, researchers can better control its behavior and use.
What are the synthesis methods of 1-ethyl-1, 2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarboxamide?
The synthesis method of 1 - ethyl - 1, 2 - dihydro - 6 - hydroxy - 4 - methyl - 2 - oxo - 3 - pyridinecarboxamide (1 - ethyl - 1, 2 - dihydro - 6 - hydroxy - 4 - methyl - 2 - oxo - 3 - pyridinecarboxamide) has been explored by many scholars in the past, and now it is yours.
One method is to use a suitable pyridine derivative as the starting material. First, the desired substituent is introduced at a specific position on the pyridine ring. For example, choose a pyridine compound with a modifiable group, and under appropriate reaction conditions, use a nucleophilic substitution reaction to introduce ethyl. Among them, the choice of reaction solvent is very critical, such as polar aprotic solvents, dimethylformamide, etc., which can promote the activity of nucleophilic reagents and make the reaction smooth.
Then, through oxidation or other functional group conversion steps, a carbonyl group is constructed on the pyridine ring. If a specific group is oxidized to a carbonyl group under the control of a suitable oxidizing agent and a suitable temperature and reaction time, this process requires fine regulation of the reaction conditions to avoid excessive oxidation.
As for the introduction of hydroxyl groups, it can be achieved by specific reduction reactions or nucleophilic addition reactions. If the raw material contains suitable unsaturated bonds or convertible groups, under suitable reagents and conditions, it can be converted into hydroxyl groups. For example, with reducing agents such as lithium aluminum hydride, the reduction of specific carbonyl groups to hydroxyl groups can be achieved in a low temperature and anhydrous and oxygen-free environment.
Furthermore, the introduction of methyl groups also has various ways. Methylating reagents, such as iodomethane, can be used under the catalysis of bases to undergo nucleophilic substitution with specific positions on the pyridine ring and introduce methyl groups.
Finally, a carboxyamide structure is formed. The group at the corresponding position on the pyridine ring can be converted into a carboxylic acid derivative, such as an acid chloride, and then reacted with ammonia or suitable amine compounds to generate the desired carboxyamide. This series of reactions requires careful consideration of the reaction conditions at each step, from temperature, solvent, reactant ratio to reaction time, all of which are related to the success or failure of synthesis and the purity of the product. In this way, the reaction with careful design and operation in multiple steps may yield 1-ethyl-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarboxamide.
1-Ethyl-1, how safe is the 2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarboxamide?
1 - ethyl - 1, 2 - dihydro - 6 - hydroxy - 4 - methyl - 2 - oxo - 3 - pyridinecarboxamide, which is an organic compound. When it comes to the safety of this compound, it needs to be investigated from many aspects.
To observe its chemical structure, the atoms it contains interact with functional groups or cause unique chemical activities. Among them, hydroxyl and carbonyl functional groups may participate in many chemical reactions. Under suitable conditions, hydroxyl groups can involve esterification, oxidation and other reactions, while carbonyl groups may interact with nucleophiles. If this compound encounters active substances in a specific environment, or has an unpredictable reaction, it may affect the surrounding environment and the objects it comes into contact with.
In living organisms, the safety of this compound also needs to be considered. When the human body comes into contact with or ingests this substance, it may undergo processes such as absorption, distribution, metabolism and excretion. Because of its specific chemical structure, or interact with biological macromolecules in living organisms, such as proteins, nucleic acids, etc. Or change the conformation of proteins, affecting their normal function; or interfere with the replication and transcription of nucleic acids, affecting the normal physiological activities of cells, and even causing toxic effects, such as cell damage, gene mutation, etc.
From an environmental point of view, if this compound is released in the environment, its behavior in different environmental media, such as soil, water, and atmosphere, also needs attention. In soil, or interact with soil particles, affecting the physical and chemical properties of soil; in water bodies, or affecting the survival and reproduction of aquatic organisms. Its degradation pathway and rate in the environment are also critical. If it is difficult to degrade or accumulate in the environment, it will have a long-term impact on the ecosystem.
However, it is difficult to make an accurate conclusion about its safety based on its name. A lot of experimental studies, such as toxicological experiments, are needed to clarify its acute, subacute and chronic toxicity to organisms; conduct environmental behavior studies to clarify its migration and transformation laws in the environment. Only in this way can we have a comprehensive and accurate understanding of the safety of 1-ethyl-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridinecarboxamide.