1-butyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile

This is an investigation into the chemical structure of 1-butyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridine-3-formonitrile. This compound belongs to a nitrogen-containing heterocyclic class derived from pyridine rings.
Looking at its structure, the first position of the pyridine ring is connected with butyl, which is a linear alkyl group containing four carbon atoms, which endows the molecule with certain hydrophobicity, which affects its solubility and interaction with other hydrophobic substances. The hydroxy group in the second position is hydrophilic and can participate in the formation of hydrogen bonds, which affects the physicochemical properties and biological activities of the compound. The methyl group at position 4 is a simple alkyl group, which affects the spatial structure and electron cloud distribution of the molecule, and plays a role in its stability and reactivity.
The carbonyl group at position 6 (C = O) has strong electron-absorbing properties, which changes the electron cloud density of the pyridine ring and affects the reactivity of the substituents on the ring. The methonitrile group at position 3 (-CN) is a strong electron-absorbing group, which not only affects the electron cloud of the pyridine ring, but also participates in various chemical reactions, such as hydrolysis and addition.
The structure of 1,6-dihydropyridine partially hydrogenates the pyridine ring. Compared with the fully conjugated pyridine ring, its electronic structure and reactivity are different. This structure partially destroys the aromaticity of the pyridine ring, endowing the compound with unique redox properties and reaction check points.
In short, the structure of this compound is composed of a pyridine ring and a variety of substituents, and the interaction of each part determines its physicochemical properties and chemical reactivity. It has potential applications in organic synthesis, medicinal chemistry and other fields.

1 - butyl - 2 - hydroxy - 4 - methyl - 6 - oxo - 1,6 - dihydropyridine - 3 - carbonitrile, this is an organic compound. Its main physical properties are as follows:
Viewed, or crystalline solid, white to light yellow, clean appearance, but the specific color may vary depending on the purity and preparation method.
Discusses the melting point, which is transformed from solid to liquid at a specific temperature due to intermolecular forces and structural characteristics. The exact melting point needs to be determined experimentally, roughly or at a certain temperature range, which is determined by molecular arrangement and interaction.
In terms of boiling point, because there are various functional groups in the structure, it affects the attractive force between molecules, so that it needs to reach a specific high temperature to overcome the intermolecular force to escape the liquid phase. However, the exact boiling point also needs to be determined experimentally.
In terms of solubility, in organic solvents such as ethanol and acetone, due to the principle of similar miscibility, or there is a certain solubility, because it contains polar and non-polar parts. However, in water, because of its strong overall non-polarity, the solubility may be limited.
Density is related to the unit volume mass, and is related to the molecular weight and the degree of packing. The exact density needs to be measured experimentally, and the approximate range can be inferred according to the chemical structure and similar compounds. < Br > The refractive index reflects the degree of refraction of light when passing through the substance, and is related to the molecular structure and electron cloud distribution. It can be measured under specific conditions, which is helpful for identification and purity analysis.
The physical properties of this compound are of great significance in the fields of chemical synthesis, separation and purification, and drug development. It can help researchers understand its behavioral characteristics and provide a basis for related applications.

1 - butyl - 2 - hydroxy - 4 - methyl - 6 - oxo - 1,6 - dihydropyridine - 3 - carbonitrile, this compound has applications in many fields.
In the field of pharmaceutical research and development, it shows potential value. Due to its specific structure, it may interact with targets in organisms. Some studies speculate that some parts of its structure can conform to the activity check point of specific enzymes, thereby regulating the activity of enzymes. For example, in inflammation-related diseases, it may be possible to inhibit some enzymes related to inflammatory mediators to exert anti-inflammatory effects; or in cancer diseases, it may inhibit the growth of tumor cells by acting on enzymes related to the proliferation of tumor cells.
In the field of materials science, it is also useful. Due to its special molecular structure, it can be used as a basic unit for the construction of new functional materials. For example, in the field of optical materials, its structural characteristics can be used to endow materials with unique optical properties, such as fluorescence properties, for the production of fluorescent labeling materials, which can help researchers in biological imaging and other aspects to accurately observe specific substances or structures in organisms.
In the field of organic synthesis, it is often regarded as an important intermediate. Because it has multiple reactive check points, it can connect different functional groups or structural fragments through a series of chemical reactions to synthesize more complex and functional organic compounds. Chemists can use this to construct molecules with unique structures and properties, providing a rich material basis for the development of new drugs and new materials.

1 - butyl - 2 - hydroxy - 4 - methyl - 6 - oxo - 1,6 - dihydropyridine - 3 - carbonitrile, the Chinese name is often 1 - butyl - 2 - hydroxy - 4 - methyl - 6 - oxo - 1,6 - dihydropyridine - 3 - formonitrile, the synthesis method is common as follows:
###Based on the synthesis strategy of nitrogen-containing heterocyclic
This compound contains pyridine rings, and the pyridine structure can be constructed by cyclization reaction from nitrogen-containing raw materials. Using β-ketonitrile compounds and suitable amines as starting materials, pyridine rings are formed by condensation and cyclization. If β-ketonitrile with appropriate substituents is selected and reacted with butylamine under appropriate conditions. An appropriate amount of catalyst is added to the reaction system, such as an organic base. Under heating conditions, β-ketonitrile and butylamine undergo nucleophilic addition first, followed by intramolecular cyclization and dehydration to form pyridine rings, thereby obtaining the target compound. This process requires precise control of the reaction temperature and time. If the temperature is too high or the time is too long, side reactions may occur, resulting in multiple substitution or over-cyclization products; if the temperature is too low or the time is too short, the reaction is incomplete.
###Stepwise construction of
1 by multi-step reaction. ** Construction of pyridine ring precursor **: Compounds containing double bonds and cyanyl groups are first prepared from simple raw materials. For example, the Michael addition reaction between acrylonitrile derivatives and acetoacetate esters under base catalysis generates intermediates containing suitable substituents and reactive. This step requires attention to the amount and type of base. Different bases will affect the reaction rate and selectivity.
2. ** Cyclization reaction **: The resulting intermediate is cyclized with butylamine under the action of an acidic or basic catalyst. If an acidic catalyst is used, the nucleophilic addition and cyclization dehydration process can be promoted; if an alkaline catalyst is used, the nucleophilic reaction may be triggered by deprotonation to promote cyclization. The reaction process needs to be monitored during the reaction process. The end point of the reaction can be judged by thin-layer chromatography to prevent impurities from overreaction.
3. ** Post-treatment and purification **: After the reaction is completed, the products are initially separated by conventional post-treatment operations such as extraction, washing, drying, etc. Then using column chromatography or recrystallization method to further purify, column chromatography to select the appropriate eluent, recrystallization to select the appropriate solvent to obtain high purity 1 - butyl - 2 - hydroxy - 4 - methyl - 6 - oxo - 1,6 - dihydropyridine - 3 - carbonitrile.

1 - butyl - 2 - hydroxy - 4 - methyl - 6 - oxo - 1,6 - dihydropyridine - 3 - carbonitrile, this is an organic compound. Its stability is related to many factors, just like the refining of ancient medicinal pills, many factors need to be considered before it can achieve positive results.
First of all, temperature is to the compound, just like heat is to alchemy. If the temperature is too high, such as cooking oil on fire, the internal energy of the molecule will surge, the chemical bond will be easily broken, and the stability will be greatly reduced. And the appropriate temperature can maintain the stability of its structure and prevent decomposition and change.
Besides pH, the pH of the environment in which this compound is located is just like the hot and cold world in which the ancients lived. The strong acid and alkali environment, like a turbulent chaotic world, will prompt the compound to react, or hydrolyze, or interact with acid and alkali substances, changing its original structure, and stability is impossible. A neutral or near-neutral mild environment is where it can live.
Solvents are also key. Different solvents, like different soils, have different solubility to compounds. If the solvent is not selected properly, the compound may be difficult to dissolve, or interact with the solvent, just like the soil where seeds are planted wrong, it is difficult to survive. A suitable solvent should be able to disperse the compound evenly without initiating a chemical reaction, so that stability can be guaranteed.
In addition, light is like the light between heaven and earth. If it is irradiated with strong light for a long time, it will provide additional energy for the compound, triggering photochemical reactions, destroying its structure and impairing its stability. Therefore, preservation away from light is also the key to maintaining its stability.
In summary, to ensure the stability of 1-butyl-2-hydroxy-4-methyl-6-oxo-1,6-dihydropyridine-3-carbonitrile, it is necessary to comprehensively consider factors such as temperature, pH, solvent and light to create a suitable environment for it, so that it can be satisfied with its own structure and not change.