1-(benzenesulfonyl)-4-bromo-2-iodo-pyrrolo[2,3-b]pyridine

This is the chemical structure analysis of 1- (benzenesulfonyl) -4-bromo-2-iodo-pyrrolo [2,3-b] pyridine. Its structure is composed of several parts cleverly combined.
First, pyrrolo [2,3-b] pyridine is the parent nuclear structure, which is a nitrogen-containing fused ring system. Pyrrole fuses with pyridine in a specific way to form a unique skeleton, giving the compound a specific spatial configuration and electronic properties.
On top of the parent nucleus, bromo atoms are connected at 4 positions. Bromo atoms have a large atomic radius and electronegativity, which have a great impact on the physical and chemical properties of molecules, such as enhancing molecular polarity, affecting their reactivity and solubility.
2 positions are connected with iodine atoms (iodo). The atomic radius of the iodine atom is larger, and the electronegativity also has characteristics, which further changes the distribution of the molecular electron cloud and affects its interaction with other molecules. It can be used as a leaving group or participate in a special bonding process in chemical reactions.
1 position is connected to benzenesulfonyl (benzenesulfonyl). The benzenesulfonyl group contains benzene ring and sulfonyl group (-SO 2O -), and the benzene ring has a conjugated system, which endows the molecule with certain stability and hydrophobicity; the sulfur atom in the sulfonyl group is in a high valence state and has strong electron absorption, which can adjust the density of the molecular electron cloud and significantly affect the chemical and biological activities of the compounds.
In summary, the chemical structure of 1- (benzenesulfonyl) -4-bromo-2-iodo-pyrrolo [2,3-b] pyridine is composed of a special fused ring mother nucleus combined with different substituents, and the interaction of each part determines the unique chemical and physical properties of the compound.

1-%28benzenesulfonyl%29-4-bromo-2-iodo-pyrrolo%5B2%2C3-b%5Dpyridine, that is, 1- (benzenesulfonyl) -4-bromo-2-iodine pyrrolido [2,3-b] pyridine, this compound is widely used in the field of organic synthesis.
First, it can be used as a key intermediate in pharmaceutical chemistry. Because of its unique structure, it contains halogen atoms such as bromine and iodine, and has a benzenesulfonyl and pyrrolidine skeleton. Halogen atoms can introduce multiple active groups through nucleophilic substitution and other reactions to modify the activity and properties of compounds. By connecting specific pharmacoactive groups, potential drug molecules with novel structures can be created for the development of anti-swelling, anti-infection and other drugs.
Second, in the field of materials science, it can be used to prepare functional materials. The pyrrolidine skeleton and benzenesulfonyl group give it special electronic properties and molecular configuration. It can be chemically modified to become a material with specific optoelectronic properties, such as being used in organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to improve its performance and improve the luminous efficiency or photoelectric conversion efficiency.
Third, in the field of organic synthesis methodology research, it is the choice of reaction substrates. Because of its structure, multiple check points have reactivity and can be used for novel organic reactions. For example, bromine and iodine atoms can participate in coupling reactions, providing new paths and methods for building carbon-carbon bonds, carbon-heteroatom bonds, etc., and promoting the development of organic synthetic chemistry.

The synthesis of 1- (benzenesulfonyl) -4-bromo-2-iodine-pyrrolido [2,3-b] pyridine is a key issue in the field of organic synthetic chemistry. To make this compound, the following steps can be followed.
First, the starting material for synthesis needs to be prepared. The synthesis of this compound is often started with pyridine or pyrrole derivatives with appropriate substituents. For example, a specific substituted pyridine can be selected, and the substituent on it is gradually converted into the desired structure of the target product through subsequent reactions.
Second, the bromination reaction is carried out. Under suitable reaction conditions, brominate the pyridine ring at a specific position in the starting material with a brominating reagent, such as bromine (Br ²) or N-bromosuccinimide (NBS). The key to this step is to precisely control the reaction conditions, such as reaction temperature, reaction time, and reactant ratio, so that the bromine atom is precisely placed in the target 4 position.
Next, carry out the iodization reaction. Using an iodine substitution reagent, such as iodine elemental substance (I2O), and an appropriate oxidizing agent, the iodine atom is introduced into the 2 positions of the pyridine ring in a suitable reaction system. This process also requires careful regulation of reaction conditions to ensure reaction selectivity and yield.
Furthermore, the benzenesulfonyl group is introduced. In general, benzenesulfonyl chloride (PhSO 2O Cl) can be used to react with an organic base, such as triethylamine (Et 🥰 N), in a suitable organic solvent. The base can assist in grabbing the hydrogen protons of the substrate, promoting the smooth connection of the benzenesulfonyl group to the first position of the pyridine ring to generate 1- (benzenesulfonyl) -4-bromo-2-iodine-pyrrolido [2,3-b] pyridine.
After each step of the reaction, purification methods such as column chromatography and recrystallization are required to obtain high-purity intermediate products and final products. In this way, the target compound 1 - (benzenesulfonyl) - 4 - bromo - 2 - iodine - pyrrolido [2,3 - b] pyridine can be obtained by carefully designed reaction steps and precise reaction conditions.

I don't know the market price of 1- (benzenesulfonyl) -4-bromo-2-iodine-pyrrolido [2,3-b] pyridine. The price of this compound or an uncommon organic synthesis intermediate is often affected by many factors.
First, the cost of raw materials is different. If the starting materials required to synthesize this compound are rare and expensive, the price of the finished product will also be high. If benzenesulfonyl, bromine and iodine substituent-related raw materials are prepared, if their supply is scarce, the cost will rise.
Second, the difficulty of synthesis has a great impact. This compound has a complex structure, and there are many synthesis steps. It needs to go through multiple reactions and the conditions of each reaction are harsh. It requires high reaction equipment and technology, so the production cost will increase greatly and the price will be high.
Third, the supply and demand relationship in the market is the key. If a certain field has strong demand for it but limited supply, merchants will raise prices due to market laws; conversely, if the demand is weak and the supply is abundant, the price will tend to be flat.
Fourth, the production scale also plays a role. In large-scale production, due to the scale effect, the unit cost may be reduced and the price may be more affordable; in small-scale production, the cost is difficult to reduce and the price is relatively high.
However, I have checked the list and quotations of common chemical reagent suppliers, but I have not found a clear price for this specific compound. For details, you may need to consult a professional chemical reagent supplier or explore the relevant chemical product trading platform to obtain a more accurate market price.

1 - (benzenesulfonyl) - 4 - bromo - 2 - iodine - pyrrole [2,3 - b] pyridine is an organic compound. When storing and transporting, the following things should be paid attention to:
First, the storage environment must be dry. This compound has certain hygroscopicity. If the environment is humid, it may react with water and cause it to deteriorate. Therefore, it should be stored in a dry place, and the environment can be maintained dry with the help of desiccant.
Second, the temperature must also be controlled. Generally speaking, it is best to store in a cool environment to avoid high temperature. High temperature can easily cause the decomposition of the compound or accelerate its chemical reaction process, resulting in damage to its stability. Generally, a refrigerated environment of 2-8 ° C is appropriate. For details, please refer to the characteristics and related information of the compound.
Third, avoid light. Many organic compounds are sensitive to light, and this compound may be no exception. Light may cause photochemical reactions to occur, affecting its quality and structure. When storing, choose an opaque container or store it in a dark place.
Fourth, ensure that the packaging is tight during transportation. To prevent leakage, because it may be toxic and corrosive, once leaked, it will not only wear out the product, but also endanger the safety of transportation personnel and the environment. Packaging needs to be made of suitable materials that can withstand certain external shocks and temperature changes.
Fifth, it should be isolated from other substances. Do not co-store with strong oxidants, strong acids, strong bases, etc., because the compound may react violently with it and cause danger. When transporting and storing, be sure to strictly abide by relevant regulations and standards, and make labels and records for traceability and management.