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What is the chemical structure of 1,4 - Dioxino [2,3 - b] pyridine, 2,3 - dihydro- (9CI)
1% 2C4 - Dioxino% 5B2% 2C3 - b%5Dpyridine%2C2%2C3 - dihydro - (9CI) is an organic compound with a complex chemical structure. According to chemical nomenclature, the structure of this compound can be resolved as follows:
Its core structure is a nitrogen-containing pyridine ring, the pyridine ring has a six-membered ring structure, in which one carbon atom is replaced by a nitrogen atom. At the 2,3 position of the pyridine ring, a 1,4-dioxane ring is fused. This 1,4-dioxane ring is also a five-membered ring structure, and the ring contains two oxygen atoms. " 2,3-Dihydro "means the double bond hydrogenation saturation of the compound at the 2,3 position, that is, the two positions are converted from unsaturated to saturated state.
In the ancient classical Chinese words of" Tiangong Kaiwu ", this compound is like a delicate creation. Its pyridine ring is like a stable building, in which nitrogen atoms occupy key positions, like the beams and columns of the building. The fused 1,4-dioxane ring is like an exquisite pavilion built on the side of the building, connected to it and complementary to each other. Hydrogenation saturation at the 2,3 position is like a partial repair of the building, making its structure more stable. Therefore, the chemical structure of this compound exists in the world in a delicate state, containing the secrets of nature and chemistry.
What are the physical properties of 1,4 - Dioxino [2,3 - b] pyridine, 2,3 - dihydro- (9CI)
1%2C4+-+Dioxino%5B2%2C3+-+b%5Dpyridine%2C2%2C3+-+dihydro-%289CI%29, this is an organic compound. Its physical properties are quite critical, related to its application in various fields.
Looking at its appearance, it is often colorless to slightly yellow liquid, clear and translucent, like a clear spring, without impurities mixed in it. Its smell is specific, slightly irritating, just like a spicy breath, but it is not pungent and intolerable, and can be detected at a certain distance.
When it comes to density, it is slightly heavier than water, about [X] g/cm ³, like a stable stone, which can slowly sink in water. The boiling point is also characteristic, about [X] ℃, and it needs specific temperature conditions to turn it into a gaseous state. < Br >
In terms of solubility, it has good solubility in organic solvents such as ethanol and ether, just like fish get water, and can be uniformly mixed with these solvents; however, the solubility in water is not good, and the two are like oil and water, and it is difficult to melt.
The melting point is around [X] ° C. When the temperature drops to this point, the compound will solidify from liquid to solid, just like water freezes when cold.
The physical properties of this compound have important uses in chemical synthesis, drug development and other fields. During chemical synthesis, its boiling point, solubility and other properties determine the reaction conditions and the way of separation and purification; in drug development, appearance, solubility, etc. are related to the dosage form and absorption effect of drugs. All of these all highlight the importance of its physical properties.
What are the common uses of 1,4 - Dioxino [2,3 - b] pyridine, 2,3 - dihydro- (9CI)
1% 2C4 - Dioxino% 5B2% 2C3 - b%5Dpyridine%2C2%2C3 - dihydro - (9CI), this is the name of an organic compound. Its common use is related to the field of organic synthesis. In the process of organic synthesis, it is often used as a key intermediate. Due to its special molecular structure, it can participate in a variety of chemical reactions to build more complex organic molecular structures.
For example, in the preparation of some fine chemicals, this is used as a starting material. With specific reaction conditions and reagents, compounds with specific functions and properties can be gradually derived. In the field of medicinal chemistry, it may also become an important cornerstone for the development of new drugs. By modifying and modifying their structures, molecular entities with potential biological activities can be explored.
Furthermore, in the field of materials science, materials synthesized based on this compound may exhibit unique physical and chemical properties, such as optical and electrical properties, and then be applied to optoelectronic devices, sensors, and many other aspects.
It plays an important role in the fields of organic synthesis, drug development, and materials science, providing a key starting point and structural foundation for many research and applications.
What are the synthesis methods of 1,4 - Dioxino [2,3 - b] pyridine, 2,3 - dihydro- (9CI)
To prepare 1% 2C4-dioxa [2,3-b] pyridine, 2,3-dihydro - (9CI), the following methods can be adopted.
First, the compound containing the corresponding functional group is used as the starting material, and the common reactions in organic synthesis, such as nucleophilic substitution, addition, etc. Pyridine derivatives with suitable substituents and reagents containing dioxa structure fragments, under suitable reaction conditions, such as in a specific solvent, catalyzed by a specific catalyst, carry out nucleophilic substitution reaction, so that the dioxa structure is connected to the pyridine ring, and then through reduction and other steps, the structure transformation of 2,3-dihydro is achieved. < Br >
Second, the strategy of parallel construction of pyridine ring and dioxane ring can be used. Select suitable multi-functional small molecules, such as aldehyde groups, amino groups, hydroxyl groups and other groups, through a series of reactions such as condensation and cyclization, build pyridine ring and dioxane ring at the same time. For example, shilling the condensation of compounds containing aldehyde groups and amino groups to form the prototype of pyridine ring, and then through a suitable reaction, the hydroxyl groups and the like are converted into part of the structure of dioxane ring, and then modified to improve the structure of the target product.
Third, use the rearrangement reaction. Select the appropriate raw materials to make them rearrange under specific conditions to construct the special structure of the target product. If a compound with a similar skeleton but different functional group positions or connection methods is first synthesized, the rearrangement is initiated by heat, light or catalyst to rearrange the atoms or groups to the target position, and then further modified by reaction to obtain 1% 2C4 -dioxa [2,3 -b] pyridine, 2,3 -dihydro- (9CI).
The key to synthesis lies in precise control of the reaction conditions, including temperature, solvent, catalyst, etc., to ensure that the reaction proceeds according to the expected path and to improve the purity and yield of the product.
What are the safety precautions for 1,4 - Dioxino [2,3 - b] pyridine, 2,3 - dihydro- (9CI)
1% 2C4 - Dioxino% 5B2% 2C3 - b%5Dpyridine%2C2%2C3 - dihydro - (9CI), this is a special chemical, about its safety precautions, let me explain in detail.
This chemical is potentially dangerous, and you must be careful when handling it. First of all, protective equipment is essential. It is recommended to wear professional protective clothing to prevent chemicals from contacting the skin and causing damage to the skin. You also need to wear chemically resistant gloves to avoid direct contact, because it may irritate and corrode the skin. Face protection is also indispensable. Wear a protective mask to prevent chemicals from splashing into the eyes and damaging the eyes.
Furthermore, the operating environment is extremely critical. It should be operated in a well-ventilated place, and the best choice is in a fume hood. In this way, the volatile gas of chemicals can be dispersed in time, the concentration of harmful substances in the air can be reduced, and the risk of inhalation can be reduced. If inhaled inadvertently, it may cause respiratory discomfort and even cause more serious health problems.
Storage is also important. It must be stored in a cool, dry and ventilated place, away from fire and heat sources. Because of its flammable and explosive properties, if it is not careful, it will cause disaster. And it should be stored separately from oxidants, acids, alkalis, etc., to prevent mutual reaction and cause danger.
If you accidentally come into contact with this chemical during operation, you should take corresponding measures immediately. If you come into contact with the skin, rinse quickly with a large amount of flowing water, and then seek medical treatment. Eye contact, immediately lift the eyelids, rinse with flowing water or normal saline, and seek medical attention as soon as possible. If inhaled, quickly leave the scene to a fresh place of air, keep the respiratory tract unobstructed, if breathing difficulties, give oxygen, stop breathing and heartbeat, immediately perform cardiopulmonary resuscitation, and call for first aid.
In short, treat 1% 2C4 - Dioxino% 5B2% 2C3 - b%5Dpyridine%2C2%2C3 - dihydro - (9CI), must strictly follow safety procedures, do not slack in the slightest, to ensure personal safety and environmental safety.