1 4 Dihydro 5 Methoxycarbonyl 2 6 Dimethyl 4 3 Nitrophenyl Pyridine 3 Carboxylic Acid
pyridine pyrrole pyrazine piperidine piperazine

1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3-carboxylic Acid

    Specifications

    HS Code

    479981

    Chemical Formula C17H18N2O7
    Molar Mass 362.33 g/mol
    Appearance Typically a solid (description may vary based on purity and preparation)
    Melting Point Data might vary depending on purity; specific value needs experimental determination
    Solubility In Water Low solubility in water due to its non - polar nature from the aromatic and alkyl groups
    Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane, chloroform based on its lipophilic groups
    Pka Values related to its carboxylic acid groups; data may require experimental determination
    Uv Vis Absorption Absorption bands associated with the aromatic rings and nitro group in the UV - Vis spectrum
    Ir Absorption Characteristic peaks for carbonyl groups (ester and carboxylic acid), aromatic C - H, nitro group etc. in the IR spectrum

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    Frequently Asked Questions

    As a leading 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3-carboxylic Acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (3-nitrophenyl) pyridine-3-carboxylic acid?
    1% 2C4-dihydro-5-methoxybenzofuran-2% 2C6-dimethyl-4- (3-pyridylbenzyl) -3-quinoline carboxylic acid, which is a class of organic compounds of great significance in the field of medicinal chemistry. Its main uses cover the following ends.
    First, in the process of drug development, such compounds are often used as lead compounds. Due to its unique chemical structure, it can be combined with specific targets in organisms. Taking cancer treatment as an example, studies have found that it may inhibit specific protein kinases related to the proliferation of cancer cells, acting as a delicate "lock and key", accurately adapting and blocking the signaling pathway of abnormal proliferation of cancer cells, opening up new paths for the creation of anti-cancer drugs.
    Second, it also has extraordinary performance in the exploration of antibacterial drugs. It can exert antibacterial effect by interfering with key physiological processes such as bacterial cell wall synthesis and protein synthesis. Just like when resisting certain drug-resistant bacterial infections, it shows potential antibacterial activity and is expected to become a new weapon against drug-resistant bacteria and alleviate the severe situation of clinical antibacterial drug resistance.
    Third, in the field of drug research for nervous system diseases, it may regulate the release and transmission of neurotransmitters. For example, for neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, by affecting the metabolism and function of related neurotransmitters such as dopamine and acetylcholine, it provides a novel structural template for the development of therapeutic drugs for such diseases, helping to solve the problem of neurological disease treatment.
    What are the synthesis methods of 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (3-nitrophenyl) pyridine-3-carboxylic acid?
    To prepare 1% 2C4-dihydro-5-methoxypyridyl-2% 2C6-dimethyl-4- (3-furanylphenyl) -3-pyridinecarboxylic acid, the synthesis method is as follows:
    First, the corresponding pyridine derivative can be used as the starting material and prepared through a multi-step reaction. First, the pyridine compound containing a specific substituent is alkylated with a haloalkane under suitable reaction conditions, such as in a specific solvent, with a suitable base as the catalyst, and groups such as methyl are introduced to construct the substituted structure on the pyridine ring.
    Furthermore, for the formation of dihydropyridine structures, catalytic hydrogenation can be used. In the presence of suitable catalysts, such as palladium carbon, hydrogen is introduced to control the temperature, pressure and other conditions of the reaction, so that the pyridine ring is partially hydrogenated to form a 1% 2C4-dihydropyridine structure.
    As for the introduction of methoxy groups, corresponding alcohols can be selected. In an alkaline environment, nucleophilic substitution reactions are carried out with pyridine derivatives to introduce methoxy groups at the 5th position of the pyridine ring.
    For the connection of 4- (3-furanylphenyl) structures, the coupling reaction can be achieved. For example, by using the Suzuki coupling reaction catalyzed by palladium, the boronic acid containing furyl group and the pyridine derivative containing halogenated phenyl group are reacted in a suitable solvent under the action of alkali and palladium catalyst to realize the connection of this key structure.
    During the whole synthesis process, it is necessary to carefully control the reaction conditions of each step, including reaction temperature, time, proportion of reactants and solvent selection, in order to improve the yield and selectivity of the reaction, and then efficiently synthesize the target product 1% 2C4-dihydro-5-methoxypyridyl-2% 2C6-dimethyl-4 - (3-furanylphenyl) -3-pyridinecarboxylic acid.
    What are the physicochemical properties of 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (3-nitrophenyl) pyridine-3-carboxylic acid?
    1% 2C4-dihydro-5-methoxybenzimidazole-2% 2C6-dimethyl-4- (3-pyridylphenyl) -3-quinoline carboxylic acid, this physical property is quite unique. Its appearance is often crystalline and the texture is relatively stable. In terms of physical characteristics, it has a certain melting point, but the specific value will fluctuate due to purity and measurement environment. In terms of solubility, it is slightly soluble in common organic solvents such as ethanol and acetone, but it is difficult to dissolve in water. This property is closely related to the groups contained in the molecular structure.
    From the analysis of chemical properties, the structures of benzimidazole and quinoline in this compound endow it with certain aromatics and conjugated systems, making it exhibit specific activities in chemical reactions. The substituents on its benzene ring have a significant impact on the activity of electrophilic substitution, and the electronic effects of the substituents at different positions determine the check point and difficulty of the reaction. For example, methoxy as a power supply group will increase the electron cloud density of the benzene ring, making the ortho and para positions more prone to electrophilic substitution.
    Furthermore, the introduction of pyridylphenyl enriches the electron distribution and spatial structure of the molecule, which affects its interaction with other substances. This structural property makes the compound have unique properties and application potential in the fields of medicinal chemistry, materials science, etc., providing many possibilities for related research and development.
    What is the market price of 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (3-nitrophenyl) pyridine-3-carboxylic acid?
    Wen Jun inquired about the price of 1,4-dihydro-5-methoxypyridine-2,6-dimethyl-4- (3-furanyl) phenyl-3-carboxylic acid in the market. This is a fine chemical, and its price often varies depending on quality, purity, and supply and demand.
    If its purity is ordinary, it is suitable for general experiments, and the price per gram may be between tens and hundreds of dollars. However, if the purity is extremely high, it reaches the standard of pharmaceutical grade or special use, and the price will rise significantly.
    Furthermore, the purchase volume is also the key. If you buy in bulk, the unit price may be reduced due to economies of scale; if you buy in small quantities, the unit price will be higher.
    In addition, market fluctuations, rising and falling raw material costs, and difficulty in synthesis processes all affect the price. If raw materials are scarce and complex to synthesize, the price will be high; if the market is abundant and the synthesis is convenient, the price will be more affordable.
    If you want to know the exact price, you should consult chemical raw material suppliers, chemical reagent merchants, or visit relevant chemical product trading platforms to compare the quotations of each company in detail.
    What are the storage conditions for 1,4-dihydro-5-methoxycarbonyl-2,6-dimethyl-4- (3-nitrophenyl) pyridine-3-carboxylic acid?
    1% 2C4-dihydro-5-methoxybenzimidazole-2% 2C6-dimethylphenyl-4- (3-pyridyl) quinoline-3-carboxylic acid is a rare medicine. Its storage conditions are quite important, which is related to the quality and efficacy of the medicine.
    This medicine should be stored in a cool, dry and well-ventilated place. In a cool place, the temperature should not be too high to prevent the medicine from being heated and deteriorating. If it is in a warm place, the ingredients in the medicine may react chemically, causing its structure to change and its efficacy to be damaged. Generally speaking, the storage temperature should be controlled between 15 and 25 degrees Celsius. < Br >
    A dry environment is also indispensable. Moisture can easily cause deliquescence and mildew of the medicinal material. If the medicinal material is damp, not only the appearance and properties change, but also its chemical properties may change, and the active ingredients become inactivated, reducing its medicinal value. Therefore, the storage place should be moisture-proof, and a desiccant can be placed next to it to absorb excess water vapor.
    Furthermore, good ventilation can ensure the smooth flow of gas in the environment where the medicinal material is located. If turbid gas and filth gather around the medicinal material, it may have an adverse effect on it. The circulating air can protect the medicinal material from turbid gas erosion and maintain its purity.
    And the medicinal material should be placed separately from other sundries and odors to prevent its odor and contamination. Because of its chemical properties or more active, it is easy to interact with surrounding substances. When storing, it should be contained in a sealed container to further block the intrusion of external adverse factors, so as to have the best quality and ensure its effectiveness. When needed, it can perform its function.