1 4 Dihydro 2 6 Dimethyl 3 5 Pyridinedicarboxylic Acid Diethyl Ester
pyridine pyrrole pyrazine piperidine piperazine

1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester

    Specifications

    HS Code

    235046

    Chemical Formula C13H19NO4
    Molecular Weight 253.294 g/mol
    Appearance Colorless to pale yellow liquid or solid
    Boiling Point Approx. 313 - 314 °C
    Melting Point Approx. 39 - 41 °C
    Density Approx. 1.086 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
    Flash Point Approx. 135 °C
    Odor Characteristic odor

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    General Information
    Where to Buy 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester in China?
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    Frequently Asked Questions

    As a leading 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 1,4-Dihydro-2,6-dimethyl-3, 5-pyridinedicarboxylic acid diethyl ester?
    1% 2C4-dihydro-2% 2C6-dimethyl-3% 2C5-diethyl pyridine dicarboxylate, its chemical structure can be summarized as follows:
    This compound belongs to the pyridine derivative, which is in the dihydrogen state at the 1 and 4 positions of the pyridine ring, that is, the double bonds of the 1 and 4 positions of the original pyridine ring are hydrogenated to form a single bond. The 2 and 6 positions are connected to a methyl group, so there is a dimethyl group. The 3 and 5 positions are connected to a carboxylic acid diethyl ester group, and this carboxylic acid diethyl ester group is obtained by forming an ester of carboxylic acid and ethanol. That is, the carboxyl group at the 3 and 5 positions is esterified with ethanol to form the structure of -COOCH -2 CH. From a holistic perspective, the basic structure of the pyridine ring is modified, and the dihydrogen state changes the electron cloud distribution and reactivity of the ring. The introduction of methyl groups affects the steric hindrance and lipophilicity of the molecule. The carboxylic acid diethyl ester group at position 3 and 5 endows the molecule with specific chemical activities and physical properties. In the fields of organic synthesis and medicinal chemistry, such structures often attract attention due to their unique reactivity and biological activity.
    What are the main physical properties of 1,4-Dihydro-2,6-dimethyl-3, 5-pyridinedicarboxylic acid diethyl ester?
    1% 2C4 - Dihydro - 2% 2C6 - dimethyl - 3% 2C5 - pyridinedicarboxylic acid diethyl ester is an organic compound, commonly known as ethyl methoxymethylene cyanoacetate. It has many important physical properties.
    Looking at its properties, it is mostly a colorless to light yellow transparent liquid under normal conditions. This color and shape are easy to observe and operate in various experimental and industrial scenarios.
    When it comes to the boiling point, it is about 210-212 ° C. The higher boiling point indicates that the intermolecular force of the substance is strong, and it will change from liquid to gas at higher temperatures, which is of great significance in distillation, separation and other operations.
    In terms of melting point, it is about -25 ° C, and the melting point is low, which means that it can exist in liquid form at room temperature, making it easier to mix and react.
    The density of this compound is about 1.076 (g/mL, 25/4 ° C). This density data can guide its stratification and mixing ratio in solution, which can help experimenters or producers to accurately control the reaction conditions.
    Solubility is also a key property. It is soluble in organic solvents such as ethanol and ether, which facilitates its participation in organic synthesis reactions. Because many organic reactions need to be carried out in specific organic solvents, good solubility allows it to fully contact the reactants and improve the reaction efficiency.
    1% 2C4 - Dihydro - 2% 2C6 - dimethyl - 3% 2C5 - pyridinedicarboxylic acid diethyl ester plays an important role in organic synthesis, pharmaceutical and chemical industries, helping people to better use this compound to carry out various work.
    What are the common synthesis methods of 1,4-Dihydro-2,6-dimethyl-3, 5-pyridinedicarboxylic acid diethyl ester?
    The common synthesis methods of 1% 2C4-dihydro-2% 2C6-dimethyl-3% 2C5-diethyl pyridine dicarboxylate include the following categories:
    First, ethyl acetoacetate and its derivatives are used as the starting materials. This is a classic method. First, ethyl acetoacetate is reacted with the corresponding nitrogen-containing compound under suitable conditions, usually requiring a specific catalyst and an appropriate temperature and pressure environment. For example, ethyl acetoacetate is reacted with ammonia and formaldehyde derivatives, and undergoes a series of steps such as condensation and cyclization to gradually build a pyridine ring structure and finally generate the target product. In this process, the choice of catalysts is crucial, such as certain Lewis acids or bases, which can effectively promote the reaction process and increase the yield.
    Second, the reaction catalyzed by transition metals. With the development of organic synthesis chemistry, transition metal catalysis has become increasingly important. Transition metals such as palladium and copper are used as catalysts to couple halogenated aromatics or alkenyl halides with compounds containing active hydrogen, such as ethyl acetoacetate derivatives. By carefully designing the reaction substrates and ligands, the regioselectivity and stereoselectivity of the reaction can be precisely regulated, and the target product can be efficiently synthesized. However, the price of transition metal catalysts is relatively high, and the reaction conditions are relatively harsh, so the anhydrous and anaerobic environment of the reaction system needs to be strictly controlled.
    Third, the cyclization and condensation strategy is adopted. Select open-chain compounds with suitable functional groups to form pyridine rings through intramolecular cyclization and condensation reactions. For example, dicarbonyl compounds with appropriate carbon chain length and functional group distribution and ammonia or amine compounds undergo intramolecular cyclization and condensation under the action of acidic or basic catalysts to build a pyridine ring skeleton, and then introduce corresponding ester groups and methyl groups to achieve the synthesis of the target product. This method requires delicate design of the structure of the starting material to ensure that the cyclization reaction can proceed smoothly.
    In what fields is 1,4-Dihydro-2,6-dimethyl-3, 5-pyridinedicarboxylic acid diethyl ester used?
    1% 2C4-dihydro-2% 2C6-dimethyl-3% 2C5-diethyl pyridinedicarboxylate, which is useful in many fields. In the field of medicine, it is an important intermediate in organic synthesis. Geinpyridine compounds have diverse biological activities, through which they can synthesize many drugs with special curative effects, or be antibacterial drugs, or can play a key role in the development of drugs for the treatment of cardiovascular diseases, contributing to medical progress and benefit patients.
    In the field of materials science, it also shows unique value. After specific chemical reactions, it can be converted into functional materials with excellent performance. For example, in the synthesis of polymer materials, its participation in the reaction may endow the material with special optical and electrical properties, which can be used to fabricate new optoelectronic devices and contribute to the development of electronic technology.
    Furthermore, in the field of organic synthetic chemistry, it is a commonly used synthetic building block. Organic chemists can skillfully design reaction paths according to their structural characteristics to synthesize organic compounds with complex structures and unique functions, greatly enriching the variety of organic compounds, promoting the development of organic synthetic chemistry, opening up a broader field for chemical research, and deepening human understanding of the structure and properties of matter.
    What is the market outlook for 1,4-Dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester?
    1% 2C4-dihydro-2% 2C6-dimethyl-3% 2C5-diethyl pyridinedicarboxylate is a crucial compound in the field of organic synthesis. Looking at its market prospects, it is like a star shining, which is quite impressive.
    In the field of pharmaceutical research and development, this compound is like a magical key, opening the door to the creation of many drugs. Due to its unique chemical structure, it can be ingeniously combined with many biological targets, so it often plays a key role in the exploration of new drugs. For example, in the research and development process of drugs related to cardiovascular diseases and neurological diseases, it is like a shining star, providing new ideas and directions for R & D personnel, which undoubtedly indicates that it has broad room for expansion in the pharmaceutical market.
    Furthermore, in the field of materials science, it has also emerged. With the rapid development of science and technology, the demand for materials with special properties is increasing day by day. 1% 2C4-dihydro-2% 2C6-dimethyl-3% 2C5-diethyl pyridine dicarboxylate shows unlimited potential in the preparation of functional materials due to its special properties. For example, in the synthesis of optical materials and polymer materials, it can be used as an indispensable raw material, giving unique properties to materials, and then meeting the special requirements of materials in different fields, which undoubtedly has won a world in the materials market.
    In addition, with the continuous progress of the global chemical industry, the demand for fine chemicals is increasing day by day. 1% 2C4-dihydro-2% 2C6-dimethyl-3% 2C5-diethyl pyridine dicarboxylate As an important member of the fine chemical family, it is favored by many chemical companies due to its high purity and unique chemical properties. Whether it is used as an intermediate in the synthesis of other complex compounds or directly applied to specific chemical reactions, it plays a pivotal role, so it also occupies a solid position in the chemical market.
    In summary, 1% 2C4-dihydro-2% 2C6-dimethyl-3% 2C5-diethyl pyridine dicarboxylate presents a bright market prospect in many fields such as medicine, materials and chemical industry, just like a giant ship with sails, breaking through the waves in the future market ocean.