As a leading 1,2-Dihydro-5-imidazo[1,2-伪]pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 1,2-Dihydro-5-imidazo [1,2-α] pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride?
This is an investigation into the chemical structure of 1,2-dihydro-5-imidazolo [1,2-α] pyridine-6-yl-6-methyl-2-oxo-3-pyridineformonitrile hydrochloride.
This substance, according to its name, "1,2-dihydro", indicates that a specific double bond in its molecular structure has been hydrogenated, and hydrogen atoms at positions 1 and 2 are added, causing the original unsaturated bond to become saturated. " Imidazolo [1,2-α] pyridine ", which is the core parent nuclear structure, imidazolo ring and pyridine ring are connected in a specific fused way, [1,2-α] shows the fused position and direction of the two, which is the key to constructing the basic structure of this compound.
" 6-methyl ", which appears at the 6th position of the imidazolo-pyridine structure, is connected with a methyl group. The presence of this methyl group can change the physical and chemical properties of the compound, such as lipophilicity, steric resistance, etc." 2-Oxo "refers to the presence of a carbonyl group (C = O) at a specific position (2 positions), and the carbonyl group is polar, which has a significant impact on the reactivity and intermolecular forces of the compound.
" 3-pyridyl formonitrile "indicates that the 3-position of the pyridine ring is connected with a formonitrile (-CN) group, which is a strong electron-absorbing group, which can affect the electron cloud distribution of the molecule and change the reactivity and biological activity of the compound. And" hydrochloride "indicates that the compound forms a salt with hydrochloric acid. This process may be due to the presence of basic groups in the compound molecule and reacts with hydrochloric acid to form a salt. It is common in the field of medicinal chemistry to improve the solubility and stability of the compound.
In summary, the chemical structure of 1,2-dihydro-5-imidazolo [1,2-α] pyridine-6-methyl-2-oxo-3-pyridineformonitrile hydrochloride is composed of specific fused heterocyclic parent nuclei, connected with different substituents, and formed into hydrochloride forms. The parts interact to determine the properties and activities of compounds.
What are the physical properties of 1,2-Dihydro-5-imidazo [1,2-α] pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride?
1% 2C2-dihydro-5-imidazolo [1,2-α] pyridine-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile hydrochloride, which is an organic compound. Its physical properties are of great research value and are closely related to many chemical processes.
Looking at its properties, it is often crystalline, which is due to the specific arrangement of intermolecular forces. The crystalline morphology is stable, providing convenience for its storage and transportation. As for the color, it is mostly white or off-white, and this pure color may suggest that its purity is high and there are few impurities. The melting point of
is also one of the key physical properties. The melting point of this compound is clear. At a specific temperature, the thermal motion of the molecules is sufficient to overcome the lattice energy and cause the solid state to transform into a liquid state. The determination of the melting point can help chemists determine its purity. Those with high purity have a narrow melting point range; those with impurities have a reduced melting point and a wider range.
In terms of solubility, it varies in different solvents. Organic solvents such as ethanol and acetone may have a certain solubility. Due to the principle of "similar compatibility", organic molecules and organic solvent molecules can form weak interactions. The solubility in water may be limited, because the ratio of polar groups to non-polar parts in the molecular structure affects its ability to interact with water molecules. < Br >
In addition, the density of the compound is also one of the characteristics. Density reflects the mass per unit volume of a substance and is closely related to the degree of molecular packing. Accurate determination of density is of great significance for material measurement and reaction system design in the chemical industry.
In summary, the physical properties of 1% 2C2-dihydro-5-imidazolo [1,2-α] pyridine-6-yl-6-methyl-2-oxo-3-pyridineformonitrile hydrochloride, such as crystalline properties, color, melting point, solubility and density, are all important bases for chemical research and application, and help chemists understand its characteristics in depth. It plays a key role in synthesis, separation and application.
What are the main uses of 1,2-Dihydro-5-imidazo [1,2-α] pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride?
1% 2C2 - Dihydro - 5 - imidazo% 5B1% 2C2 -% CE% B1% 5Dpyridin - 6 - yl - 6 - methyl - 2 - oxo - 3 - pyridinecarbonitrile Hydrochloride, an organic compound. It is widely used in the field of pharmaceutical research and development, and is mostly used as an active ingredient to explore compounds with specific biological activities, or can be used to create new drugs to treat certain diseases. For example, in the study of anti-tumor drugs, scientists hope to explore the potential of inhibiting tumor cell growth by exploring the structure and activity of the compound.
In the field of chemical synthesis, this compound may serve as a key intermediate for the preparation of other more complex organic molecules. Chemical craftsmen can use ingenious chemical reactions to build diverse chemical structures and enrich the types of organic compounds.
In scientific research and exploration, it is also an important tool for scientists to study related chemical reaction mechanisms and molecular interactions. By observing the chemical reactions it participates in, it can gain insight into many chemical laws and contribute to the development of chemical theory. The properties and uses of organic compounds often depend on their fine chemical structure and unique reactivity. By virtue of their structural characteristics, this compound has shown potential important value in many fields such as medicine, synthetic chemistry and scientific research.
What is the synthesis method of 1,2-Dihydro-5-imidazo [1,2-α] pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride?
1% 2C2 - Dihydro - 5 - imidazo% 5B1% 2C2 -% CE% B1% 5Dpyridin - 6 - yl - 6 - methyl - 2 - oxo - 3 - pyridinecarbonitrile Hydrochloride, that is, 1,2 - dihydro - 5 - imidazolo [1,2 - α] pyridine - 6 - yl - 6 - methyl - 2 - oxo - 3 - pyridineformonitrile hydrochloride, the synthesis method is as follows:
The starting material is often selected from suitable pyridine derivatives and imidazole derivatives. First, the pyridine derivative is functionalized in a specific way, introducing the desired substituent at a specific position in the pyridine ring, such as cyano at the 3-position and methyl at the 6-position. This step can be achieved by nucleophilic substitution with the corresponding halogenated cyanide and methylation reagent under appropriate reaction conditions.
For imidazole derivatives, it needs to be activated to enable condensation with pyridine derivatives. Generally, a suitable reactivity check point is created at the 1,2-position of the imidazole ring.
Subsequently, the treated pyridine derivative and the imidazole derivative are condensed in a suitable solvent, such as dichloromethane, N, N-dimethylformamide, etc., under the catalytic action of a base. The base can be selected from potassium carbonate, sodium carbonate, etc., and the reaction temperature is controlled in a suitable range, such as room temperature to about 60 ° C, and the reaction time varies from several hours to ten hours, which prompts the formation of 1,2-dihydro-5-imidazolo [1,2-α] pyridine-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile structure.
Finally, the obtained product is treated with hydrochlorination, and hydrogen chloride gas is introduced into the reaction system or a suitable hydrochloric acid solution is added to convert the product into 1,2-dihydro-5-imidazolo [1,2-α] pyridine-6-yl-6-methyl-2-oxo-3-pyridineformonitrile hydrochloride. After crystallization, filtration, drying and other post-processing steps, the target product can be obtained. The whole synthesis process requires strict control of the reaction conditions and the operation of each step to ensure the purity and yield of the product.
What are the safety precautions for 1,2-Dihydro-5-imidazo [1,2-α] pyridin-6-yl-6-methyl-2-oxo-3-pyridinecarbonitrile Hydrochloride?
1% 2C2 - Dihydro - 5 - imidazo% 5B1% 2C2 -% CE% B1% 5Dpyridin - 6 - yl - 6 - methyl - 2 - oxo - 3 - pyridinecarbonitrile Hydrochloride is a special chemical substance. It needs to be treated with caution due to its safety precautions.
This chemical may be chemically active and touch the skin. It may cause irritation, redness, itching in light cases, rash or ulceration in severe cases. Therefore, when handling this product, be sure to wear protective gloves. The material is better to resist its corrosion. After operation, wash your hands with water and soap as soon as possible to ensure that there is no residue.
If it is not carefully entered into the eye, it is particularly harmful, and can damage the eye tissue, causing blurred vision, pain and even blindness. Once so, rinse immediately with plenty of water, and be sure to fully open the eyelids to ensure thorough rinsing, and then seek medical attention immediately.
Inhaling its dust or volatile gaseous substances should not be ignored, or irritate the respiratory tract, causing cough, asthma, breathing difficulties, etc. In the operating environment, when ensuring good ventilation, wear appropriate respiratory protective equipment, such as gas masks, and filter elements must be adapted to the chemical.
Furthermore, this chemical substance may be flammable. Fireworks are strictly prohibited in storage and use, and it should be kept away from fire and heat sources to prevent accidents. And it should be stored in a cool, dry and ventilated warehouse, separated from oxidants, acids, alkalis, etc., and must not be mixed to avoid dangerous reactions.
During operation, all utensils and equipment used must be clean and free of other chemical residues to prevent impurities from causing accidents. At the same time, operators should be familiar with emergency treatment methods and know how to respond quickly and correctly in the event of an accident to minimize harm.