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What is the chemical structure of 1,2,4-triazolo [4,3-a] pyridine-3 (2H) -one?
1%2C2%2C4-%E4%B8%89%E5%94%91%E5%B9%B6%5B4%2C3-a%5D%E5%90%A1%E5%95%B6-3%282H%29-%E9%85%AE%E7%9A%84%E5%8C%96%E5%AD%A6%E7%BB%93%E6%9E%84%E6%98%AF%E4%B8%80%E7%A7%8D%E5%A4%9A%E7%82%B9%E7%82%B9%E7%9A%84%E5%A4%8D%E6%9D%82%E7%BB%93%E6%9E%84%E7%94%A8%E7%89%A9%E4%BD%93%E7%BB%93%E6%9E%84%E5%BC%8F%E8%A1%A8%E7%A4%BA%E5%88%99%E6%98%AF%E5%A6%82%E4%B8%8B%EF%BC%9A
This compound has a fused polycyclic structure containing three union rings. Its core structure is three connected ring systems, two of which are six-membered rings, and the other may be five-membered rings or other rings, which are merged in a specific [4,3-a] way. "1,2,4-triazine" indicates that one of the rings is a six-membered heterocycle composed of three nitrogen atoms and three carbon atoms, and the nitrogen atoms are at positions 1, 2, and 4.
"-3 (2H) -keto" means that there is a carbonyl group (C = O) at the position numbered 3, and the hydrogen atom at this position has a specific chemical environment (2H means that two hydrogen atoms are in the specific chemical environment at this position). In the whole structure, each atom is connected to each other through covalent bonds to form a stable three-dimensional spatial structure. The spatial arrangement of atoms and the distribution of electron clouds determine the unique physical and chemical properties of the compound.
The complexity of the structure of the compound endows it with potential diverse chemical activities, which may have important research value and application prospects in the fields of organic synthesis, medicinal chemistry and so on. Its unique structure may cause it to interact with specific biological targets, thus exhibiting specific biological activities that could be used to develop novel drugs or as a key intermediate in organic synthesis.
What are the main physical properties of 1,2,4-triazolo [4,3-a] pyridine-3 (2H) -one?
1% 2C2% 2C4-triazino [4% 2C3-a] pyridine-3 (2H) -one is an organic compound. It has the following main physical properties:
- ** Appearance and properties **: It is mostly solid under normal conditions, and the intermolecular force is strong and the stability is high due to the molecular structure. However, due to different substituents, the appearance may be different, or it is a white crystalline powder or a white solid, which is related to the molecular aggregation state and the scattering and absorption characteristics of light. < Br > - ** Melting point and boiling point **: The melting point is higher, or between 150 ° C and 300 ° C. Due to the conjugated system and strong hydrogen bonds, van der Waals forces, etc. in the molecule, high energy is required to destroy the lattice. The boiling point is also relatively high, between 300 ° C and 450 ° C. Due to the conversion of liquid to gaseous state, intermolecular forces must be overcome.
- ** Solubility **: In view of the polar atoms such as nitrogen and oxygen, it has a certain solubility in polar solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), and can interact with solvents to form hydrogen bonds. However, in non-polar solvents such as n-hexane and benzene, the solubility is small, and it is difficult to match the intermolecular forces due to the large polar difference. < Br > - ** Density **: The density may be between 1.2 and 1.5 g/cm ³, which is determined by the molecular composition and structure. It contains more atoms with large relative atomic mass and close molecular stacking, resulting in a higher density.
- ** Spectral properties **: In the ultraviolet-visible spectrum, due to the existence of conjugated systems, there are characteristic absorption peaks, or in the range of 250-350 nm, which can be used for qualitative and quantitative analysis. In the infrared spectrum, the vibration of chemical bonds such as nitrogen-hydrogen, carbon-hydrogen, carbon-nitrogen, and carbon-oxygen has corresponding absorption peaks, which is helpful for structural identification.
In what fields is 1,2,4-triazolo [4,3-a] pyridine-3 (2H) -one used?
1%2C2%2C4-%E4%B8%89%E5%94%91%E5%B9%B6%5B4%2C3-a%5D%E5%90%A1%E5%95%B6-3%282H%29-%E9%85%AE, this compound has extraordinary applications in medicine, materials science and other fields.
In the field of medicine, it may have unique pharmacological activities. Ancient physicians tasted the cloud: "The effect of medicine is related to the cure of the disease." This compound has been studied and may play a role in specific diseases, such as certain inflammation and tumor diseases. Its structural properties enable it to precisely bind to biological targets in the body, like the fit between a key and a lock, or regulate cell signaling pathways, or inhibit abnormal cell proliferation, and then achieve therapeutic purposes.
In the field of materials science, "the quality of the material is good or bad, and the quality of the device is good or bad." This compound may be used as a key component of functional materials. Because of its special chemical structure, it may endow the material with unique electrical and optical properties. For example, it can be used to prepare new photoelectric materials, and in photoelectric devices such as Light Emitting Diode and solar cells, its photoelectric conversion efficiency can be improved, which is like injecting vitality into the device and improving its performance to a higher level.
Furthermore, in the field of organic synthesis, it is also an important intermediate. "The beauty of synthesis is like the carving of a craftsman." With its structural characteristics, it can be derived through ingenious chemical reactions. A variety of organic compounds with diverse structures and functions are derived, which is like using it as a cornerstone to build a building of complex organic compounds, contributing to the development of organic synthetic chemistry.
What are the synthesis methods of 1,2,4-triazolo [4,3-a] pyridine-3 (2H) -one?
1% 2C2% 2C4-triazino [4% 2C3-a] pyridine-3 (2H) -one can be synthesized by the following methods.
First, the triazine-pyridine skeleton is constructed by condensation reaction with nitrogen-containing heterocyclic compounds as starting materials. For example, select appropriate pyridine derivatives and nitrogen-containing heterocyclic reagents, and under the action of suitable temperature and catalyst, the two condensate. This process requires precise regulation of reaction conditions. Too high or too low temperature and improper catalyst dosage may reduce the reaction yield or generate by-products. For example, a specific pyridine derivative and a nitrogen-containing heterocyclic reagent are condensed to form an intermediate product under mild heating and catalysis of a certain type of metal catalyst, and then modified by subsequent reactions, the target product can be obtained 1% 2C2% 2C4-triazino [4% 2C3-a] pyridine-3 (2H) -one.
Second, it is prepared by cyclization reaction. A chain compound with a suitable functional group is used as the starting material, and the target cyclic structure is formed by intramolecular cyclization. During this process, the activity of the functional group, the reaction solvent and the reaction time all have a great influence on the cyclization reaction. For example, a chain compound containing multiple active functional groups, in a specific organic solvent, under the catalysis of basic conditions, after a certain period of time, the molecular cyclization occurs, and then 1% 2C2% 2C4-triazine [4% 2C3-a] pyridine-3 (2H) -one is synthesized.
Third, a multi-step series reaction is used. First, a simple compound is used as a raw material, and a complex structure is gradually constructed through multi-step reaction, and finally the target product is obtained. Although this method is cumbersome, it can precisely control the structure of the product. For example, a simple compound is introduced into a specific group through substitution reaction, and then through a series of reactions such as addition and cyclization, 1% 2C2% 2C4-triazino [4% 2C3-a] pyridine-3 (2H) -one is gradually synthesized. Each step of the reaction requires strict control of the reaction conditions to ensure that the reaction proceeds in the desired direction to improve the yield and purity of the target product.
What is the market outlook for 1,2,4-triazolo [4,3-a] pyridine-3 (2H) -one?
1%2C2%2C4-%E4%B8%89%E5%94%91%E5%B9%B6%5B4%2C3-a%5D%E5%90%A1%E5%95%B6-3%282H%29-%E9%85%AE%E7%9A%84%E5%B8%82%E5%9C%BA%E5%89%8D%E6%99%AF%E8%8B%A5%E4%B8%8B%E6%89%80%E8%BF%B0:
This is a unique chemical substance, and its market prospect is influenced by many factors. In the field of medicine, if it can be confirmed that it has unique pharmacological activity, or has a definite effect on specific diseases, it can arouse strong interest from pharmaceutical companies, invest in research and development resources, and develop new treatment pathways. The prospect is quite promising.
In the field of materials science, if its structure endows the material with unique properties, such as excellent stability, conductivity or optical properties, it can be widely used in electronic and optical materials, etc. The market demand will increase significantly.
However, there are challenges ahead for the market of this substance. The synthesis process may be complex and costly, limiting large-scale production and promotion. And new substances need to be approved by strict regulations to ensure safety and effectiveness, which is time-consuming and laborious.
Furthermore, the market competition situation should not be underestimated. If similar functional alternatives have occupied the market, they need to show outstanding advantages in order to stand out. To grasp its market prospects, it is necessary to deeply explore its performance, optimize synthesis technology, pay close attention to regulations and policies, and accurately evaluate the competition landscape, so as to find development opportunities in the unpredictable market.