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What is the chemical structure of (+) - (S) - (o-chlorophenyl) -6,7-dihydrothieno [3,2-c] pyridine-5 (4H) -acetic acid, hydrochloride
The chemical structure of (+) - (S) - (o-chlorophenyl) -6,7-dihydrothiopheno [3,2-c] pyridine-5 (4H) -acetic acid hydrochloride is like a delicate mechanism, which needs to be carefully investigated by chemical reasons.
In this compound, (+) indicates that it has optical rotation and is a dextrote; (S) indicates the configuration of its chiral center. " (o-chlorophenyl) " indicates that there is a chlorine-containing phenyl group attached at a specific position, and the chlorine atom is connected to the benzene ring, like a delicate component embedded in the overall structure.
6,7-dihydrothiopheno [3,2-c] pyridine-5 (4H) moiety is formed by fusing thiophene ring with pyridine ring. The state of dihydro implies partial unsaturation, and there is a reactive check point. 4H indicates the numbering position of a specific hydrogen atom on the pyridine ring, which determines an important identification for the structure.
The acetic acid moiety, containing a carboxyl group structure, and the state of -COOH give this compound a certain acidity and reactivity. The form of hydrochloride means that it binds to hydrochloric acid and exists as a salt, changing its physical and chemical properties, such as solubility. The overall structure of this compound, each part is interrelated, like an ancient mechanism, which together determine its unique chemical properties and reaction behavior.
What are the physical properties of (+) - (S) - (o-chlorophenyl) -6,7-dihydrothieno [3,2-c] pyridine-5 (4H) -acetic acid, hydrochloride
(+) - (S) - (o-chlorophenyl) -6,7-dihydrothiopheno [3,2-c] pyridine-5 (4H) -acetic acid hydrochloride, this is an organic compound. Its physical properties are quite critical and are of great significance in chemical research and practical applications.
Looking at its properties, it may be white to off-white crystalline powder at room temperature and pressure. This form is easy to store and use, and also reflects the order of its molecular arrangement.
Melting point is an important index for judging the purity and characteristics of this compound. The melting point may be within a specific range determined by experiments. This temperature range is characterized by the break of the equilibrium of intermolecular forces when heated and the disintegration of the lattice structure.
Solubility is also an important property. In water, its solubility may be limited due to the hydrophobicity of some groups in the molecular structure; however, in organic solvents such as ethanol and dichloromethane, it may have good solubility. This property is conducive to the separation, purification and reaction medium selection of reactants or products in organic synthesis reactions.
In terms of stability, under normal storage conditions, if there are no extreme factors such as light, high temperature and high humidity, the compound can maintain a relatively stable chemical structure. When exposed to specific chemical reagents such as strong acids, strong bases or strong oxidizing agents, chemical reactions may occur and cause structural changes.
In addition, although its physical properties such as density and refractive index are relatively less mentioned, they can also provide an important basis for the identification and application of the compound in specific fields such as materials science and analytical chemistry. Density reflects the degree of close packing of molecules, and refractive index is related to its effect on light propagation characteristics.
In summary, the physical properties of (+) - (S) - (o-chlorophenyl) -6,7 -dihydrothiopheno [3,2 -c] pyridine-5 (4H) -acetic acid hydrochloride are complex and diverse, and each property is interrelated, which together determine its behavior and application in the field of chemistry.
What is the main use of (+) - (S) - (o-chlorophenyl) -6,7-dihydrothieno [3,2-c] pyridine-5 (4H) -acetic acid, hydrochloride
(+) - (S) - (o-chlorophenyl) -6,7-dihydrothiopheno [3,2-c] pyridine-5 (4H) -acetic acid hydrochloride, which has a wide range of uses. In the development of medicine, it can be used as a key intermediate to help create new specific drugs. Taking the development of drugs for the treatment of neurological diseases as an example, it may be able to use its own unique chemical structure to regulate specific neurotransmitter receptors, thereby illuminating new ideas and directions for drug development for diseases such as epilepsy and Parkinson's disease.
In the field of organic synthesis, it is an important synthetic building block, which can use a variety of chemical reactions to construct complex organic molecules with specific structures and functions. For example, through condensation and substitution reactions with other compounds containing active groups, organic materials with novel structures and excellent properties are generated, which contributes to the progress of materials science.
At the same time, in pharmaceutical chemistry research, structural modification and modification can deeply explore the internal relationship between structure and activity, laying a solid foundation for the design and synthesis of ideal drugs with better efficacy and fewer side effects. With its unique chemical properties and structural characteristics, it has shown indispensable value in many scientific research and industrial production fields.
What are the synthesis methods of (+) - (S) - (o-chlorophenyl) -6,7-dihydrothieno [3,2-c] pyridine-5 (4H) -acetic acid, hydrochloride
(+) - ( S) - (o-chlorophenyl) -6,7-dihydrothiopheno [3,2-c] pyridine-5 (4H) -acetic acid hydrochloride synthesis is the key to chemical preparation. To obtain this compound, several routes can be followed.
First, a compound containing thiophene and pyridine structures is used as the starting material. After a halogenation reaction under specific reaction conditions, a chlorine atom is introduced at a suitable position to form the key structure of o-chlorophenyl. Then, the parent nucleus of thiophene and pyridine is hydrogenated to promote the formation of 6,7-dihydrothiopheno [3,2-c] pyridine structure. Then, the acetic acid group is introduced at position 5 by means of a carboxylation reaction. This step requires fine regulation of reaction conditions, such as temperature, solvent, and catalyst type and dosage. Finally, the hydrochloric salt form of the target product is obtained by reacting with hydrochloric acid into a salt.
Second, you can also start with the construction of the thiophenopyridine parent nucleus. First, through a clever cyclization reaction, the basic structure of thiopheno [3,2-c] pyridine is established. Then, o-chlorophenyl and acetic acid groups are introduced in sequence, and the reaction selectivity and yield must be paid attention to in each step. When introducing o-chlorophenyl, nucleophilic substitution or electrophilic substitution reactions can be used, depending on the activity of the specific starting material. The introduction of an acetate group can be achieved by reacting with an intermediate with a suitable acylating reagent. Finally, it interacts with hydrochloric acid to form a hydrochloride salt.
When synthesizing this compound, the control of various reaction conditions is of paramount importance. The temperature, the length of the reaction time, the ratio of reactants, and the characteristics of the solvent and catalyst used all have a significant impact on the reaction process and product purity. And after each step of the reaction, it is necessary to use separation and purification methods such as column chromatography, recrystallization, etc., to ensure the purity of the intermediate and the final product, so as to obtain high-quality (+) - ( S) - (o-chlorophenyl) -6,7 -dihydrothiopheno [3,2 -c] pyridine-5 (4H) -acetic acid hydrochloride.
What is the market outlook for (+) - (S) - (o-chlorophenyl) -6,7-dihydrothieno [3,2-c] pyridine-5 (4H) -acetic acid, hydrochloride?
(+) - (S) - (o-chlorophenyl) -6,7-dihydrothiopheno [3,2-c] pyridine-5 (4H) -acetic acid hydrochloride, this compound has considerable potential in the current market prospects.
Looking at the past, many drug development fields have favored heterocyclic compounds with special structures. This compound contains thiophenopyridine structures and has emerged in the field of drug creation. In terms of pharmacological activity exploration, many studies have focused on its potential biological activities. For example, in the field of neurological disease drugs and cardiovascular disease drug development, this structure has shown unique effects, or can interact with specific targets, laying the foundation for the development of new drugs.
When it comes to the market, with the increasing aging of the global population and the growing demand for the treatment of various diseases, the market demand for new drugs is vast. Due to its novel structure, if this compound can be successfully developed into a drug, it may open up new paths in the treatment of related diseases and occupy a certain market share. Furthermore, it is also of great value as a drug synthesis intermediate. Many pharmaceutical companies and scientific research institutions continue to increase the demand for novel intermediates in order to develop innovative drugs with high efficiency and low toxicity. (+) - (S) - (o-chlorophenyl) -6,7-dihydrothiopheno [3,2-c] pyridine-5 (4H) -acetic acid hydrochloride may become a popular choice, bringing it a broad market space. However, its market development also faces challenges, such as high research and development costs and high clinical trial risks, which require practitioners to respond cautiously in order to make it stand out in the market.