[R-(R*,R*)]-2,6-Bis(4,5-dihydro-4-phenyl-2-oxazolyl)pyridine

This compound [R- (R *, R *) ] -2,6-bis (4,5-dihydro-4-phenyl-2-oxazolyl) pyridine is widely used in various fields of chemistry.
In the field of catalysis, it often acts as a chiral ligand. Chiral ligands have a great impact on the activity and selectivity of metal catalysts. With its unique structure, this compound can form stable complexes with metal atoms. It exhibits high enantioselectivity in asymmetric catalytic reactions and obtains products with specific configurations. It has made great contributions to drug synthesis and total synthesis of natural products. For example, in the synthesis of some chiral drug key intermediates, the catalytic system of this compound as a ligand can efficiently prepare the required chiral structural units to improve drug activity and safety.
In the field of materials science, it also has applications. Because the compound has a rigid planar structure and nitrogen heterocycle, it can participate in the construction of functional materials. For example, when preparing organic Light Emitting Diode (OLED) materials, its structural properties can be used to improve the luminescence properties and stability of the materials. Its structure can be modified, and the electronic and optical properties of the materials can be adjusted by adjusting the substituents, so that the materials can meet different application needs.
In the field of supramolecular chemistry, this compound can self-assemble with other molecules through intermolecular interactions, such as hydrogen bonds, π-π stacking, etc., to build an ordered supramolecular structure. This supramolecular structure has potential applications in molecular recognition, sensing, etc. For example, the design of supramolecular sensors with high selectivity recognition ability for specific molecules, and the specific combination of target molecules, to achieve highly sensitive detection of target molecules.

[R- (R *, R *) ] -2,6-Bis (4,5-dihydro-4-phenyl-2-oxazolyl) pyridine is a class of substances that have attracted much attention in the field of chemistry. Its physical properties are unique and play a key role in many chemical reactions and material synthesis.
Looking at its appearance, it is often in the state of white to light yellow crystalline powder, which is delicate and uniform in quality, and shines slightly under light, just like fine pearls. Its melting point is in a specific range, between about 150 ° C and 155 ° C. This temperature limit is like a precise scale, marking the node of the material's transition from solid to liquid. When the temperature gradually rises near the melting point, the substance is like a quietly melting ice and snow, gradually transforming from a solid state to a flowing liquid state, and there is no obvious color change during this transition.
In addition, this substance also has characteristics in terms of solubility. It can show good solubility in organic solvents such as chloroform and dichloromethane, just like a fish entering water, it quickly fuses with the solvent to form a uniform and transparent solution. However, in water, its solubility is poor, just like oil floating in water, it is difficult to melt. This property is due to the dominance of hydrophobic groups in its molecular structure.
Its density is also an important physical property, about 1.2 - 1.3 g/cm ³, giving the substance a certain relationship between mass and volume. This density value affects the distribution and interaction of substances in many reaction systems or material constructions, just as the density of building cornerstones affects the stability and structure of the entire building.
In terms of chemical stability, this substance is relatively stable under general conditions, and it is not easy to react with common components in the air such as oxygen and carbon dioxide. It is like a calm old man who is not easily moved by the outside world. However, under certain conditions, such as strong acid and alkali environments, or extreme situations such as high temperature and strong light, its structure may change, and its chemical properties will also change, which will lead to different chemical reactions and generate different products.

To prepare this [R- (R *, R *) ] -2,6-bis (4,5-dihydro-4-phenyl-2-oxazolyl) pyridine, the method is as follows:
Take the pyridine as the group first, and introduce the appropriate group at its 2,6 position. This step requires fine operation, considering the activity of the pyridine ring and the selectivity of the reaction check point. Pyridine is often halogenated at 2,6 positions with specific halogenating reagents to obtain 2,6-dihalopyridine intermediates.
Then, 4,5-dihydro-4-phenyl-2-oxazolyl-related precursors are prepared. Using benzaldehyde and glycine as starting materials, the active intermediate of 4,5-dihydro-4-phenyl-2-oxazolyl was obtained through various reactions such as condensation and cyclization.
Then the intermediate of 2,6-dihalopyridine and the active intermediate of 4,5-dihydro-4-phenyl-2-oxazolyl are reacted under suitable catalysts and reaction conditions. Palladium catalysts are often used, and the choice of ligands is also critical, which can help improve the selectivity and efficiency of the reaction. In a suitable solvent, factors such as temperature and reaction time are controlled to make the two coupling reactions occur, so that the target product can be obtained.
However, during the reaction process, it is necessary to pay attention to the precise control of the reaction conditions in each step, and the removal of impurities cannot be ignored. After separation and purification, such as column chromatography, recrystallization, etc., to obtain high-purity [R- (R *, R *) ] -2,6-bis (4,5-dihydro-4-phenyl-2-oxazolyl) pyridine.

Today there is a thing called [R- (R *, R *) ] - 2,6 - Bis (4,5 - dihydro - 4 - phenyl - 2 - oxazolyl) pyridine, what is the market price?
This is a special compound in the field of fine chemicals, and it is quite complicated to price it in the market. Its price is determined by the number.
First, the cost of raw materials. For the preparation of this compound, if the raw materials used are rare and difficult to find, or the extraction and synthesis are not easy, the price will be high. If the raw materials are common and easy to produce, the cost will be slightly reduced.
Second, the preparation process. If the preparation method is complicated, multiple reactions are required, and the reaction conditions are strict, such as precise temperature and pressure, high-purity solvents, professional catalysts, etc., the manpower and material resources are expensive and the price is also high. If the process is simple, the cost can be reduced.
Third, the supply and demand of the market. If there is a large demand for this product in the fields of pharmaceutical research and development, material science, etc., and the supply is limited, the price will rise. On the contrary, if the supply exceeds the demand, the price may decline.
Fourth, the difference in quality. High purity and high quality, due to the difficulty of preparation, can meet high-end applications, and the price is higher than that of ordinary quality.
However, after checking the past market records, the exact price of this specific compound was not found. To know its price, you should consult a merchant specializing in fine chemicals, or research relevant chemical trading platforms, or consult with industry experts to obtain a near-real price.

This substance [R- (R *, R *) ] -2,6-bis (4,5-dihydro-4-phenyl-2-oxazolyl) pyridine, its storage conditions are extremely critical. This is a fine chemical product and needs to be stored in a cool, dry and well-ventilated place. Be sure to avoid direct sunlight, because light can easily cause chemical reactions of the substance, affecting its chemical structure and properties.
Temperature control is also the focus, and the ideal storage temperature should be maintained between 15 and 25 degrees Celsius. If the temperature is too high, it may accelerate the movement of molecules and cause them to react with components in the air; if the temperature is too low, it may cause the substance to crystallize and solidify, changing its physical state and affecting subsequent use.
Furthermore, it is necessary to ensure that the storage environment is dry. Due to its sensitivity to humidity, humid air can easily absorb moisture and cause adverse reactions such as hydrolysis, which can reduce purity and quality. It is recommended to store in a sealed container with desiccant to maintain a dry environment.
In addition, the storage area should be away from fire, heat sources and strong oxidants. This substance may be flammable, and it is easy to cause danger in case of open flames and hot topics; strong oxidants may also react violently with it, resulting in safety accidents. At the same time, the storage place should be clearly marked to prevent accidental touch and misuse, and to ensure the safety of personnel and material quality is not damaged.