4 Chlorophenyl Pyridine 2 Methanol
pyridine pyrrole pyrazine piperidine piperazine

伪-(4-chlorophenyl)pyridine-2-methanol

    Specifications

    HS Code

    426809

    Chemical Formula C12H10ClNO
    Molar Mass 219.67 g/mol
    Appearance Solid (usually white or off - white)
    Melting Point Typically in a certain range (data needed for exact value)
    Boiling Point Data required for exact value
    Solubility In Water Low solubility (usually sparingly soluble)
    Solubility In Organic Solvents Soluble in some common organic solvents like ethanol, dichloromethane
    Density Data needed for exact value
    Pka Data required for exact value
    Logp Data needed for exact value

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    Frequently Asked Questions

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    What are the chemical properties of pseudo- (4-chlorophenyl) pyridine-2-methanol?
    (The chemical properties of pseudo- (4-cyanobenzyl) pyridine-2-formaldehyde are the characteristics it exhibits in chemical reactions. This substance contains functional groups such as cyanide group (-CN) and aldehyde group (-CHO), which give it unique chemical activity.)
    The aldehyde group has strong reductive properties and can undergo many reactions. For example, it can react with weak oxidants such as silver ammonia solution with silver mirror. In this reaction, the aldehyde group is oxidized to carboxyl group, and the silver ion in the silver ammonia complex ion is reduced to metallic silver, which is attached to the inner wall of the container to form a silver mirror. The reaction process is quite delicate, just like a wonderful change in the microscopic world. < Br >
    can also react with the new copper hydroxide suspension to form a brick-red precipitate of cuprous oxide. This reaction also results in the oxidation of the aldehyde group, while the valence of the copper element in the copper hydroxide decreases, showing the properties of the aldehyde group as a reducing agent under specific conditions.
    Cyanyl also has its own characteristics. It can undergo hydrolysis under specific conditions to form products such as carboxyl groups. This process is like a cyanyl group quietly changing in a suitable environment, opening a new chemical journey.
    As a whole, (pseudo- (4-cyanobenzyl) pyridine-2-formaldehyde) can participate in many organic synthesis reactions due to the existence of these functional groups, and plays an important role in the field of organic chemistry. Its chemical properties are like the key to opening the door to the microscopic chemical world, leading chemists to explore more amazing reaction paths and synthesis methods, thus laying the foundation for new material research and development, drug synthesis and many other fields, promoting the continuous development of chemistry, and bringing more benefits to human society.
    What are the common synthesis methods of pseudo- (4-chlorophenyl) pyridine-2-methanol?
    The common synthesis methods of pseudo- (4-cyanobenzyl) pyridine-2-formamide are various, and today they are described in ancient Chinese.
    First, cyanobenzyl is used as the beginning, and the hydrogen of the benzyl group is halogenated to be replaced by a halogen atom. After halogenation, it reacts with pyridine-2-formamide under the catalysis of a base. This product can be obtained by combining the two with a base, such as potassium carbonate and sodium carbonate, in a suitable solvent, such as N, N-dimethylformamide, dimethylsulfoxide, etc., at a suitable temperature, or in the state of heating and reflux. The reaction mechanism is that the halogen atom of halogenated benzyl is quite active, and it is easy to be attacked by the nucleophilic group of pyridine-2-formamide, so as to form bonds.
    Second, pyridine-2-formyl chloride can be reacted with amine compounds containing cyanobenzyl. First, pyridine-2-formyl chloride is prepared, and pyridine-2-formyl acid is reacted with chlorinated reagents such as thionyl chloride and phosphorus oxychloride. Then, pyridine-2-formyl chloride and cyanobenzyl-containing amine react slowly in inert solvents such as dichloromethane and chloroform at low temperature. Among them, the carbonyl group of the acid chloride is active, and the nitrogen atom of the amine is nucleophilic. The combination of the two, the hydrogen chloride is removed, and the target product is obtained.
    Third, the coupling reaction catalyzed by transition metals is used. For example, in a palladium catalytic system, select suitable palladium catalysts, such as palladium acetate, tetra (triphenylphosphine) palladium, etc., with suitable ligands, such as tri-tert-butylphosphine, bipyridine and the like. Coupling with pyridine-2-formamide derivatives containing cyanobenzyl halide or borate in a base and a suitable solvent. This method requires precise control of reaction conditions, temperature, catalyst dosage, ligand ratio, etc. are all related to the success or failure of the reaction and the yield. Its advantage is that the reaction selectivity is good, and the carbon-nitrogen bond can be effectively constructed to obtain the desired pseudo- (4-cyanobenzyl) pyridine-2-formamide.
    In which fields is pseudo- (4-chlorophenyl) pyridine-2-methanol used?
    (Pseudo- (4-cyanobenzyl) pyridine-2-acetylnitrile is useful in many fields.) Although it is not directly and in detail discussed in Tiangong Kaiwu, its application can be explored based on current scientific knowledge and past records.
    In the field of pharmaceutical and chemical engineering, this compound has a wide range of uses. Its structural characteristics make it a key intermediate and participate in many drug synthesis processes. For example, the preparation of specific anti-cancer drugs, with its unique chemical properties, can effectively react with other molecules, build a drug active structure, and help the drug to precisely attack cancer cells and improve the anti-cancer efficacy.
    In the field of materials science, it also has application potential. The polymer material system can be introduced through specific processing. It can improve the electrical properties of the material, so that the material can exhibit better conductivity, insulation and stability in the field of electronic component manufacturing, such as the production of high-performance capacitors, semiconductor materials, etc., and expand the application scenarios of materials.
    Furthermore, in the field of organic synthesis chemistry, (4-cyanobenzyl) pyridine-2-acetonitrile is an important organic reagent and is often used to construct complex organic molecular structures. Organic chemists use their participation in various reactions, such as nucleophilic substitution, addition reactions, etc., to skillfully design and synthesize organic compounds with specific functions and structures, injecting vitality into the development of organic synthetic chemistry and promoting the development and preparation of new organic materials, fragrances, and other substances.
    What is the market price of pseudo- (4-chlorophenyl) pyridine-2-methanol?
    (What is the market price of pseudo- (4-cyanobenzyl) pyridine-2-formate ethyl ester?)
    The market price of (4-cyanobenzyl) pyridine-2-formate ethyl ester is the key to commercial trade and industrial circulation. However, its price is not constant and often fluctuates with many factors.
    First, the trend of supply and demand affects its price. If the market is above, the demand for this compound is strong, and the supply is limited, just like the rain in a drought, the price will rise. On the contrary, if the supply exceeds the demand, such as flooding, the price will be at risk of falling.
    Second, the price of raw materials is also a major factor. If the price of all raw materials required for the preparation of (4-cyanobenzyl) pyridine-2-ethyl formate rises, such as chai rice is more expensive than in the past, the cost of this compound will increase, and the merchant will increase the price in order to ensure profitability.
    Third, changes in the current situation and policy changes also have an impact. War chaos, traffic blockage, poor logistics, or policy regulation and production restrictions can all cause price volatility.
    Fourth, technological innovation and process improvement, if production efficiency can be improved and costs reduced, such as skilled craftsmen making good use of new devices, prices may also be reduced.
    As for the current specific price, it is difficult to say exactly because there is no real-time market information. If you want to know the details, you can consult the chemical raw material trading market, related industry guilds, or professional business information platforms, where there should be more accurate price quotations.
    What are the storage conditions for pseudo- (4-chlorophenyl) pyridine-2-methanol?
    (What are the storage conditions of pseudo- (4-cyanobenzyl) pyridine-2-formamide? Please simulate "Tiangong Kaiwu" to answer this question in classical Chinese format, about 500 words, direct text, no title and conclusion.)
    If you want to store pseudo- (4-cyanobenzyl) pyridine-2-formamide well, you should study its properties in detail and go with the flow. Although this materiality is not explicitly stated in ancient scrolls, it can be roughly deduced from today's reasons.
    The first weight avoids moisture. Cover water vapor is easy to invade various substances and cause deterioration and decay. Therefore, when storing this amide, it is advisable to choose a place with high dryness, not near water or wetlands. If it is in a humid place, water vapor gradually seeps, or causes it to hydrolyze, destroying its essence and losing its use. It is like a house leaking and wet millet, and the millet will be moldy and rotten, and it cannot be eaten.
    Times need to be protected from light. Light, a kind of energy, or the structure of a cataclysmic substance. If this amide is exposed to light for a long time, it may cause photochemical reactions, causing its chemical properties to change. If the silk is exposed to the hot sun, the silk color is easy to darken, and the quality is easy to be brittle, all of which are harmful to light. It is necessary to cover it with something that blocks light, or hide it in a dark room, and enter without light.
    Furthermore, temperature is also If it is overheated, the molecular activity will increase greatly, and the reaction will be easy to produce; if it is too cold, it may cause its crystalline morphology to change, which will also damage its properties. It is advisable to find a cool place with moderate temperature, so that this amide can exist safely. Just like a person in a suitable place for cold and heat, the body is healthy and healthy, and the same is true for things. If it is suitable for temperature, it will be stable.
    And it should be prevented from mixing with other things. Different substances have different properties, and miscellaneous parts may react. This amide is stored alone and does not combine with acids, bases, strong oxidants, etc. If different drugs are co-placed in one container, changes will occur, and the drug resistance will be obedient.
    In summary, the storage of pseudo- (4-cyanobenzyl) pyridine-2-formamide should be in a dry, dark, cool place, and not mixed with other things, so that its quality can be preserved for future use.