[4-(3-Methylphenyl)Amino]Pyridine-3-Sulfoamide

There is a compound named\ [5B4- (3-methylphenyl) amino\] pyridine-3-sulfonamide, and its chemical structure is wanted to know. In this compound, the pyridine ring is its core structure, which is like the pillar of a building, laying its basic framework. At the 3rd position of the pyridine ring, there is a sulfonamide group, which is formed by connecting the sulfonyl group with the amino group, which is like adding a unique decoration to the pillar. And at the 4th position of the pyridine ring, there is an amino group with 3-methylphenyl as a substituent, which is like an oblique branch escaping from the side, giving the compound a different characteristic. In the methylphenyl group, the phenyl group has a benzene ring structure, which has a conjugated system, which makes the electron cloud distribution of the compound unique; the methyl group is attached to the third position of the benzene ring, further changing its spatial structure and electronic effect. Such various structural elements are interconnected to form the chemical structure of\ [5B4- (3-methylphenyl) amino\] pyridine-3-sulfonamide, which makes it have a variety of chemical properties of pyridine, sulfonamide and methylphenyl, showing unique properties and uses in chemistry and related fields.

[4- (3-methylphenyl) amino] pyridine-3-sulfonamide is an important member of the field of organic compounds. It has a wide range of uses in the field of medicinal chemistry and is often used as a key intermediate in drug research and development. Due to its unique chemical structure, it can interact with specific targets in organisms, thereby regulating physiological processes, and is expected to develop effective drugs for specific diseases, such as anti-cancer and anti-infective drugs.
In the field of materials science, it also shows potential application value. Or it can be used as a synthetic raw material for functional materials, giving materials special electrical, optical or mechanical properties. For example, with the help of its structural properties, it can participate in the construction of organic materials with special electrical conductivity for the manufacture of electronic devices; or endow materials with sensitivity and responsiveness to specific substances for the preparation of high-performance sensor materials.
In addition, in agricultural chemistry, there are also areas that can be explored. It may be possible to develop bioactive compounds by modifying the structure for crop pest control, and compared with traditional pesticides, or have higher selectivity and lower environmental toxicity, contributing to the development of green agriculture. In short, [4- (3-methylphenyl) amino] pyridine-3-sulfonamide has broad application prospects and research value in many fields due to its unique structure.

To prepare [4- (3-methylphenyl) amino] pyridine-3-sulfonamide, the method is as follows:
First take an appropriate pyridine derivative. The pyridine derivative needs to have a suitable group that can be substituted by the sulfonamide group at the 3rd position of the pyridine ring, and a group that can be substituted by the (3-methylphenyl) amino group at the 4th position. Usually such groups can be halogen atoms, such as chlorine atoms.
Take 3-halo-4-halopyridine, take 3-chloro-4-chloropyridine as an example, combine it with 3-methylaniline in a suitable solvent, such as N, N-dimethylformamide (DMF), and add an appropriate amount of alkali, such as potassium carbonate, etc., to heat up and stir the reaction. The function of the base is to capture the hydrogen of 3-methylaniline to form a nucleophilic reagent, attack the halogen atom at the 4th position of the pyridine ring, and undergo a nucleophilic substitution reaction to generate 4- (3-methylphenyl) amino-3-halopyridine. Subsequently, 4- (3-methylphenyl) amino-3-halopyridine is reacted with sulfinates, such as sodium sulfite, in appropriate solvents and conditions. This reaction requires temperature control, pH and other conditions to replace the halogen atom with a sulfonyl group, thereby generating [4- (3-methylphenyl) amino] pyridine-3-sulfonate.
Finally, [4- (3-methylphenyl) amino] pyridine-3-sulfonate is acidified with an acid, such as hydrochloric acid, to obtain the target product [4- (3-methylphenyl) amino] pyridine-3-sulfonamide. The whole process requires fine control of the reaction conditions, and also has certain requirements for the purity of raw materials and reaction equipment, so that the reaction can proceed smoothly and a higher yield product can be obtained.

The physical properties of [4- (3-methylphenyl) amino] pyridine-3-sulfonamide are crucial.
Looking at its appearance, it is mostly white to white crystalline powder, which is its intuitive appearance and easy to distinguish visually.
When it comes to solubility, it has a certain solubility in organic solvents, such as common ethanol and dichloromethane. This property is similar to that of many organic compounds, allowing it to participate in reactions or perform separation and purification operations in specific solvent systems. In water, its solubility is relatively limited, mainly due to the influence of hydrophobic groups in its molecular structure, but a small amount can also be dispersed. < Br >
In terms of melting point, it has been finely determined to be around [specific melting point value] ° C. This melting point is its inherent physical constant and can be used for purity identification. If the purity is extremely high, the melting point should be relatively sensitive and close to the theoretical value; if it contains impurities, the melting point may be deviated, and the melting range will also become wider.
In terms of density, it is about [specific density value] g/cm ³. This density value has important reference significance when considering its mixing with other substances, separation, or storage and transportation in specific containers.
Furthermore, its stability is also worth mentioning. Under normal temperature and humidity conditions, it is relatively stable. However, if exposed to strong acids, strong bases, or extreme conditions of high temperature and high humidity, the molecular structure may change, causing changes in properties.
These physical properties are of great value in chemical synthesis, drug development, materials science and many other fields, and can help researchers better control their applications and provide strong support for the development of related fields.

[4- (3-methylphenyl) amino] pyridine-3-sulfonamide, which is a chemical substance. The current market prospect of the company can be described as both opportunities and challenges.
In the field of scientific research, this substance has attracted the attention of many researchers due to its unique chemical structure. With the advancement of chemical synthesis technology, its synthesis process has gradually matured and its purity has been continuously improved, providing better raw materials for scientific research. Therefore, it has broad application prospects in basic research such as pharmaceutical chemistry and materials science. For example, in the development of new drugs, it may become a key intermediate to help create drugs with better efficacy and fewer side effects. Therefore, in the scientific research market, demand is expected to rise steadily.
However, when it is put into the field of industrial production, it faces many obstacles. On the one hand, in large-scale production, existing equipment needs to be retrofitted and upgraded to meet the requirements of its production process, which will cost a huge amount of money and increase production costs; on the other hand, safety production and environmental protection requirements are strict, and the waste treatment generated in the production process is quite difficult. If it is not careful, it will cause environmental problems, be punished by regulatory authorities, and cause enterprises to face economic and reputation losses, thus restricting their promotion in industrial large-scale production.
Furthermore, from the perspective of market competition, with the deepening of relevant research, similar or alternative products continue to emerge, and the competition is becoming increasingly fierce. If an enterprise wants to gain a foothold in the market, it needs to continue to invest in research and development, improve product quality, optimize production processes, and reduce costs to enhance its own competitiveness.
In summary, the [4- (3-methylphenyl) amino] pyridine-3-sulfonamide market has a bright future, but the road ahead is full of thorns, and all parties need to be cautious in order to find development opportunities in the complex market environment.