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What are the main effects of tetramethylpyrazine?
Tetramethylpyrazine, also known as ligustrazine, is a good medicine for promoting blood circulation and removing blood stasis. It has many effects. In terms of qi and blood operation, it has the ability to promote qi and blood circulation. It can smooth qi and blood, make qi and blood flow continuously, and dissipate blood stasis block. Cover the body's qi and blood is important in circulation. If the qi and blood are not smooth, various diseases will occur. Tetramethylpyrazine can adjust qi and blood to relieve the disease of stasis.
In terms of veins, tetramethylpyrazine can clear the collaterals and relieve pain. Human meridians are like networks all over the body. If the veins are blocked, it will be painful if they are blocked. This medicine can dredge the meridians, make the meridians unobstructed, relieve the pain caused by the blockage of the meridians, such as headache, limb pain, etc., can be conditioned by it.
In the brain orbital, it has the power of awakening the brain. The human gods depend on the nourishment of the brain. If the qi and blood in the brain are not smooth, and the gods are nourished, it can cause dizziness and dizziness. Tetramethylpyrazine can improve the supply of qi and blood to the brain, wake the brain and enlighten the mind, make the mind clear and the mind refreshed, which is beneficial for the prevention and treatment of brain diseases.
And tetramethylpyrazine can also regulate the rheological properties of blood, reduce blood viscosity, make blood run more smoothly, and reduce the risk of thrombosis. In the cardiovascular system, it can dilate coronary arteries, increase coronary blood flow, improve myocardial ischemia, and provide protection for the normal operation of the heart. In modern medical research, it is widely used in many fields such as cardiovascular and cerebrovascular diseases, and plays an important therapeutic role.
What diseases is tetramethylpyrazine used in?
Tetramethylpyrazine, known as tetramethylpyrazine, is widely used in medicine. In the case of stroke, its effect is very good. Stroke, Qi and blood inversion, cerebral arterial obstruction or blood overflow in the brain. Ligustrazine has the ability to promote blood circulation and qi, remove blood stasis and clear collaterals, can smooth the operation of qi and blood, relieve the stagnation of veins, help the recovery of damaged cerebral collaterals, and promote the gradual recovery of limb function.
It is also often used in the disease of chest paralysis and heartache. Chest paralysis, mostly due to cardiac arterial obstruction. Ligustrazine can communicate the qi and blood of the heart, disperse its stasis, relieve heartache, and can adjust the rhythm and protect the function of the heart, so that the qi and blood of the heart can flow smoothly.
Furthermore, in the disease of vertigo, if it is caused by internal obstruction of blood stasis and the absence of clear yang, ligustrazine can also be used. Its blood-activating power can remove blood stasis, raise yang, nourish the boss, and relieve vertigo.
And in the diseases of blood vessel obstruction, such as limb numbness, convulsion pain, etc., ligustrazine can play the effect of activating blood circulation and clearing collaterals, making meridians unobstructed, qi and blood harmonized, and all diseases can be solved. It can expand blood vessels, reduce blood viscosity, and inhibit platelet aggregation, which is significant in improving blood circulation. Therefore, it is effective in a variety of diseases caused by blood stasis and is often used by doctors.
What are the side effects of tetramethylpyrazine?
Tetramethylpyrazine has a refreshing taste and warm nature, and belongs to the meridians of the liver, heart and lung. Although this substance has many effects, it also has some side effects, which cannot be ignored.
Its side effects are the first to bear the brunt of the impact on the stomach. Some people use it, or feel stomach discomfort, sometimes nausea and vomiting, or even cause abdominal pain and diarrhea. Because of its warm dryness, it is easy to disturb the peace of the stomach and cause abnormal transportation.
Secondly, it may have an effect on the blood system. Tetramethylpyrazine has the ability to promote blood circulation. If the dosage is improper, it may cause bleeding. Such as bleeding gums, ecchymosis under the skin, etc., in people with poor coagulation function, it is especially necessary to be cautious.
In addition, it may cause allergic reactions. For those with specific constitution, after exposure to this medicine, the skin can see red rash, itching, and even the respiratory tract can be involved, causing shortness of breath, chest tightness and breathlessness, etc., endangering health.
In addition, long-term or excessive use of it may affect the balance of yin and yang in the body. Because of its temperature, it is easy to exhaust gas and injure yin, causing the body to appear yin deficiency and internal heat, such as dry mouth and throat, five hearts upset and hot, etc.
Therefore, when using tetramethylpyrazine, it must be prudent. Doctors need to carefully observe the patient's physique and symptoms, take precise medication, and pay close attention to the reaction after medication, and make timely adjustments in order to achieve the purpose of treating the disease and avoid its side effects.
What is the optimal dose of tetramethylpyrazine?
Tetramethylpyrazine, also known as ligustrazine, has the effect of promoting blood circulation and qi, dispelling wind and relieving pain, and is mostly used for chest paralysis, heartache, rheumatism and pain. However, the optimal dosage is still inconclusive, due to individual differences, severity of disease, disease type and other factors.
According to clinical studies, some of them are aimed at people with mild cardiovascular and cerebrovascular disease. Oral administration of 60 to 120 mg per day, divided into 2 to 3 times, can improve blood circulation. If it is intravenous drip, for patients with severe disease, the usual dose is 80 to 160 mg, diluted with 5% or 10% glucose injection and slowly infusion.
Those who have blood stasis and obstruction during the recovery period of stroke have ligustrazine combined with conventional therapy, oral dose of 120 mg per day, and treatment with time will gradually recover the patient's limb function. In the treatment of angina pectoris in coronary heart disease, intravenous drip of 120 mg can relieve chest tightness and chest pain.
However, the elderly, children, pregnant women and breastfeeding women have special constitutions and need to be cautious in medication. The function of the viscera of the elderly is gradually declining, and the viscera of children is delicate. Pregnant women and nursing mothers are related to fetuses and infants. Dosage selection should follow the doctor's advice and should not be determined.
In summary, the best dosage of tetramethylpyrazine must be determined by the doctor according to the specific situation of the patient. Do not take it at will to avoid delaying the disease or causing adverse reactions.
What are the sources of tetramethylpyrazine?
Tetramethylpyrazine (tetramethylpyrazine), also known as ligustrazine, its sources are quite rich, and it has dabbled in both natural and artificial ways.
In the natural environment, many plants are its important sources. Chuanxiong, this is a perennial herb of the Ligusticaceae family, and its rhizomes have long been famous in the field of traditional Chinese medicine. Chuanxiong is rich in tetramethylpyrazine, which is often used in traditional Chinese medicine to promote blood circulation and qi, remove wind and relieve pain. "The words of Materia Medica" say: "Ligusticum, the leader of the ascending, down-regulating meridian water, opening stagnation in the middle, and qi medicine in the blood." The active ingredient tetramethylpyrazine is indispensable. Salvia miltiorrhiza also contains tetramethylpyrazine. Salvia mil In addition, tetramethylpyrazine can also be found in traditional Chinese medicinal materials such as Panax notoginseng.
In the process of artificial synthesis, with the advancement of modern science and technology, scientists can use chemical synthesis methods to prepare tetramethylpyrazine. By means of organic synthesis, tetramethylpyrazine can be precisely obtained from specific chemical raw materials through a series of reaction steps. This way can be produced on demand to meet a large number of needs in the pharmaceutical industry and other fields, laying the material foundation for the wide application of tetramethylpyrazine.
