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What is the main function of Sulfapyrazinemethoxyine?
Sulfamethoxydiazine (Sulfamethoxydiazine), non-Sulfapyrazinemethoxyine (this is a misspelling), has antibacterial effect. The reason for its action is to compete with p-aminobenzoic acid (PABA) for dihydrofolate synthase, causing bacteria to fail to synthesize dihydrofolic acid, which in turn affects nucleic acid synthesis and inhibits bacterial growth and reproduction.
Sulfamethoxydiazine has a wide range of antibacterial spectrum, such as Escherichia coli, Klebsiella, Staphylococcus aureus, haemolytic streptococcus and other Gram-positive and negative bacteria. In clinical practice, it is mostly used for the prevention and treatment of livestock and poultry Escherichia coli, salmonellosis, pasteurellosis, staphylococcosis, etc., and is also commonly used in the prevention and treatment of coccidiosis. < Br >
Its application is quite extensive, and it should be noted when using it. It may cause allergic reactions, and long-term and large-scale application may easily lead to the production of drug-resistant bacteria, or affect animal hematopoietic function. When using medication, follow the doctor's instructions and abide by the usage and dosage to ensure the safety and effectiveness of medication.
What are the side effects of Sulfapyrazinemethoxyine?
Although sulfapyrazine methoxy gene is a drug, it has many potential side effects and cannot be ignored.
First, it can cause allergies. If people take it, they may develop a rash, itching is intolerable, and even exfoliative dermatitis can be caused, endangering life. This is because the human immune system mistakenly regards it as a foreign body and fights it, resulting in allergies.
Second, it hurts the blood system. Or it causes a sharp decrease in the number of white blood cells and platelets, both of which are crucial to the human body. White blood cells are the guardians of defense against foreign enemies, and platelets are responsible for coagulation. If their number is reduced, the human body is prone to diseases, and the coagulation is slow after injury, and there is a risk of bleeding. < Br >
Third, it involves the liver and kidneys. The liver is a detoxification device, and the kidneys excrete it. This drug may disturb the normal metabolism of the liver and cause abnormal liver function; in the kidneys, it may form crystals, block the urinary tract, cause renal colic, hematuria and other diseases.
Fourth, it affects the digestive system. People who take the drug often feel nausea, vomiting, loss of appetite, and even diarrhea. This is because the drug stimulates the gastrointestinal mucosa, causing gastrointestinal disorders.
Fifth, it also affects the nervous system. Or make people headache, dizziness, and difficulty concentrating. If taken for a long time, it may cause more serious neurological symptoms. Therefore, when using the sulfapyrazine methoxy gene, the doctor should carefully observe the patient's physique, weigh the pros and cons, and the patient should also follow the doctor's advice. They must not use the drug without authorization to avoid side effects.
What are the applicable groups of Sulfapyrazinemethoxyine?
Sulfamethoxydiazine (Sulfamethoxydiazine), as the ancient saying goes: This medicine is suitable for the population, covering the following categories.
First, it is used for people with respiratory tract infections. The evil of wind and cold invades the body, causing lung health loss, cough, expectoration, fever and other diseases frequently occur. Sulfamethoxydiazine can remove evil and detoxify, regulate the decline of the lungs, relieve such discomfort, and help restore righteousness.
Second, it is also suitable for people with intestinal infections. The diet is unclean, and the evil of dampness and heat accumulates in the colonic tract, causing abdominal pain, diarrhea, diarrhea and other diseases. This medicine can clear away heat and dampness, reconcile gastrointestinal qi, make intestinal function return to normal, and relieve pain.
Third, it should be used in patients with urinary tract infections. Humid heat is injected into the bladder, causing urinary frequency, urgency, urinary pain and other diseases. Sulfadiazine-p-methoxypyrimidine can clear the damp heat, clear the water, and improve the diseases of the urinary tract.
However, it needs to be clarified that pregnant women, breastfeeding women and those who are allergic to sulfadiazine drugs should use or avoid this drug with caution. Because it may damage the fetus, or cause toxicity in the milk, endangering the baby; if allergic people use it, they may cause all kinds of changes and cannot be ignored. When taking the drug, they should also follow the doctor's advice and do not increase or decrease the dose by themselves, so as not to fail to achieve the drug or cause other diseases.
What is the usage and dosage of Sulfapyrazinemethoxyine?
Sulfamethoxydiazine is a commonly used sulfonamide drug. Its usage and dosage vary according to different diseases and patient conditions.
In the treatment of general bacterial infections, adults usually take two grams orally at the beginning, and then one gram a day, divided into one to two times. Children are calculated according to their body weight, and the initial dose is fifty milligrams per kilogram of body weight, and then twenty-five milligrams per kilogram of body weight, once a day.
If used to prevent meningitis, adults should take one gram orally every day for three days; children should take twenty-five milligrams per kilogram of body weight every day for three days.
When taking drugs, you must follow the doctor's advice. The doctor should accurately determine the usage and dosage according to the specific situation of the patient, such as age, weight, severity of the disease, liver and kidney function, etc. And during the medication period, it is advisable to closely observe the patient's reaction. If there are adverse reactions, such as allergies, gastrointestinal discomfort, blood system abnormalities, etc., the medicine should be stopped immediately and properly disposed of. In addition, this medicine may interact with other medicines, and the doctor should be informed of the medicine used before medication to prevent adverse consequences.
Sulfapyrazinemethoxyine interact with other drugs?
Sulfadiazine (Sulfapyrazinemethoxyine) is an antibacterial agent. As for whether it interacts with other drugs, this is a matter for doctors and drug users to pay attention to.
Considering pharmacology, sulfadiazine may interact with various drugs. When used with anticoagulants, or to enhance the anticoagulant effect of anticoagulants, it can replace the anticoagulant bound to plasma proteins, resulting in an increase in the free concentration in the blood. Therefore, when used in combination, the dose of anticoagulants may need to be adjusted. Combined use with oral hypoglycemic drugs may also enhance the hypoglycemic effect, because sulfonamide can compete for the protein binding site of methoxypyrimidine, making the hypoglycemic drugs more free and easy to cause hypoglycemia.
Furthermore, when taken with methotrexate, methotrexate can increase the blood concentration and toxicity. Because it interferes with methotrexate secretion from the renal tubules and reduces its excretion, the combination of the two should be used with caution. And if used in combination with thiazide diuretics, it can increase the risk of hypokalemia. Cosulfonamide drugs have the effect of excreting potassium, and in combination with thiazide diuretics, it is more likely to reduce the blood potassium.
When taking medication, the doctor must carefully review the medications taken by the patient, weigh the pros and cons, and prescribe cautiously to avoid the harm of drug interactions and hope to receive safe and effective treatment. Medications should also follow the doctor's advice and do not use drugs at will. If you have any doubts, consult a doctor in time to ensure the safety of medication.