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What are the indications of Sulfachoropyrazine Sodium?
Sodium sulfachloropyrazine is commonly used in veterinary medicine. Its indications are quite wide, and it is widely used in livestock diseases.
In birds, it is mainly used to prevent and treat coccidiosis. Coccidiosis, often causes intestinal damage in birds, affects digestion and absorption, causes growth retardation, and even a large number of deaths. Sodium sulfachloropyrazine can effectively inhibit the reproduction of coccidiosis, reduce the damage of coccidia to intestinal mucosa, and restore the health of birds. Chickens and ducklings are first infected with coccidia, and they see mental weakness, loose feathers, blood in the stool, etc., and they are given this medicine to perform multi-potency.
In rabbits, it is also used to prevent and control coccidiosis. Rabbits are delicate by nature and are vulnerable to coccidiosis. Sulfachloropyrazine sodium can protect the health of rabbits by inhibiting the synthesis of folic acid in the insect body and hindering the growth of coccidiosis. When rabbits are infected with diseases, or suffer from loss of appetite, diarrhea, and anemia, this drug can relieve the symptoms and promote recovery.
In addition, sulfachloropyrazine sodium is also effective for livestock infections caused by some sensitive bacteria. Intestinal infections caused by Escherichia coli, Salmonella, etc. can reduce inflammation, control the development of the disease, and help livestock restore balance and return to health.
Sulfachoropyrazine Sodium Usage and Dosage
Sulfachloropyrazine is used in combination with sodium, and its usage and dosage are quite exquisite.
The combination of the two is mostly applied to livestock diseases. Taking avian coccidiosis control as an example, it is often used in mixed feeding or mixed drinking. When mixed feeding, the amount of sulfachloropyrazine sodium added to every 1000 kg of feed varies according to the growth stage of the birds and the severity of the disease. If young birds are attacked by coccidiosis, generally 300-500 grams of sulfachloropyrazine sodium should be added to every 1000 kg of feed for 3-5 days, which can effectively inhibit and kill coccidiosis and relieve the discomfort caused by coccidiosis in young birds, such as mental weakness and diarrhea.
Adult birds prevent coccidiosis during the epidemic period. The amount added to each 1000 kg of feed is about 100-200 grams, and it can be used for 5-7 days to build a defense line and prevent coccidiosis from breeding and reproduction. If adult birds are already sick, the dosage should be increased to 300-400 grams per 1000 kg of feed for 3-5 days to control the disease and help them recover.
As for the method of mixed drinking, it also needs to be precisely prepared. Generally speaking, the content of sodium sulfonamchloropyrazine per liter of water should be 0.1-0.2 grams for young birds, 0.05-0.1 grams per liter of water for adult birds for prevention, and 0.1-0.15 grams per liter of water for treatment. Drink continuously according to the corresponding number of days.
When using drugs, you must strictly follow the dosage and do not increase or decrease it without authorization. Excessive administration may cause poisoning in livestock, damage their liver and kidney functions, and adverse reactions such as reduced feeding and depression; if the dosage is insufficient, it will be difficult to achieve the expected therapeutic effect and delay the disease. And during the medication period, it is advisable to pay close attention to the status of livestock. If there is any abnormality, you should immediately stop the medication and seek veterinary treatment.
What are the Adverse Reactions of Sulfachoropyrazine Sodium
The combination of sulfachloropyrazine and sodium salt has no opposite reaction in many cases. The two are often used in the prevention and treatment of coccidiosis in livestock.
Sulfachloropyrazine is a sulfadiamine anticoccidial drug, which has effects on all developmental stages of coccidiosis and can effectively inhibit the growth and reproduction of coccidiosis. The sodium salt is often used to assist in dissolution and regulate pH. When the two are combined, the drug can be more easily dissolved, improve bioavailability, and enhance efficacy.
Under normal dosage and normal medication conditions, there is usually no adverse interaction between the two. However, when using drugs, the principle of moderation must also be followed. If the overdose is used or the medication is used for too long, even if there is no direct opposite reaction between the two, it may also cause adverse reactions in livestock, such as affecting the balance of intestinal flora and damaging liver and kidney function. And different livestock breeds and individual conditions also have different tolerances to the drug. When taking medication, it is necessary to follow the guidance of a veterinarian and accurately control the dose and course of treatment to ensure the safety and efficacy of medication.
What are the precautions when using Sulfachoropyrazine Sodium
When using sulfa chloropyrazine in combination with sodium salts, many things need to be paid attention to.
First, know the suitability of the two. These two are often used in the prevention and treatment of specific diseases such as avian coccidiosis, and must not be used at will for other diseases. It is necessary to accurately judge according to the diseases of livestock and poultry. If used improperly, not only the disease is difficult to cure, but also adverse consequences.
Second, use the dose accurately. The dose is related to curative effect and safety. If the dosage is too small, it is difficult to contain the disease; if the dosage is too large, it is easy to cause poisoning of livestock and poultry. It should be applied accurately according to the type, weight, and severity of the disease of livestock and poultry, and strictly refer to the instructions or follow the instructions of the veterinarian.
Third, pay attention to the application time Do not use it continuously for a long time to prevent the drug from remaining in the body, endangering the health of livestock and poultry, and easily causing pathogens to develop resistance. Generally, it is used according to the prescribed course of treatment. If the disease is not cured at the end of the course of treatment, it is necessary to re-examine and adjust the medication plan.
Fourth, pay attention to the contraindications of compatibility. Do not mix with certain drugs at will. In case of alkaline drugs, or cause the solubility of sulfonamchloropyrazine to decrease, precipitate crystals, and damage the kidneys and other organs of livestock and poultry. Before using the drug, be sure to clarify whether it is compatible with other drugs.
Fifth, during the application period, closely observe the condition of livestock and poultry. If livestock and poultry have abnormal manifestations, such as listlessness, loss of appetite, diarrhea, etc., or adverse drug reactions, the drug should be stopped immediately and
Sixth, pay attention to the withdrawal period. Before livestock and poultry are slaughtered, they must strictly abide by the withdrawal period regulations to ensure that animal products have no drug residues and ensure food safety.
What are the pharmacological effects of Sulfachoropyrazine Sodium?
Sodium sulfachloropyrazine has unique pharmacological uses. It is effective in coccidiosis of livestock and poultry. Coccidiosis has disturbed the health of livestock and poultry for a long time, and sodium sulfachloropyrazine can prevent the development and reproduction of coccidiosis, so as to protect the health of livestock and poultry.
This drug is injected into livestock and poultry, absorbed through the gastrointestinal tract, and distributed to various tissues and body fluids. Its pharmacological mechanism is to compete for dihydrofolate synthetase and hinder the production of dihydrofolate. Dihydrofolate is an important substance in nucleic acid synthesis, and the proliferation of coccidia is inhibited if it is deficient.
The effect of sodium sulfachloropyrazine is true to a variety of coccidiosis. It has the ability to control both small intestinal coccidia and cecal coccidia. When used, according to the type of livestock and poultry, the severity of the disease, determine the dose and usage. Can be mixed in feed, can also be dissolved in drinking water, so that livestock and poultry get the right amount of medicine, in order to achieve the best effect. And its action speed, can control coccidiosis in a short time, reduce the pain of poultry and livestock, promote their recovery, and maintain the benefit of breeding.
