Methoxy Methylpyrazine
pyridine pyrrole pyrazine piperidine piperazine

(Methoxy)methylpyrazine

    Specifications

    HS Code

    891660

    Chemical Formula C6H8N2O
    Molar Mass 124.14 g/mol
    Appearance Colorless to pale yellow liquid
    Odor Nutty, earthy, roasted aroma
    Boiling Point 170 - 172 °C
    Density 1.065 g/cm³ (at 20 °C)
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
    Flash Point 67 °C
    Vapor Pressure Low vapor pressure at room temperature
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
    Where to Buy (Methoxy)methylpyrazine in China?
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    Frequently Asked Questions

    As a leading (Methoxy)methylpyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of (Methoxy) methylpyrazine?
    (Methoxy) methylpyrazine has a wide range of uses. In the field of fragrances, it has a unique aroma and is often a key ingredient in the preparation of characteristic flavors. In the food industry, it can increase the flavor of food, give it a different flavor, and add attractive charm. For example, it can be used in baked goods, meat products, etc., to make its aroma more rich and mellow.
    In the field of chemical synthesis, (methoxy) methylpyrazine is also an important intermediate. With its chemical properties, it can be derived from various compounds with specific properties through various reactions, expanding the path for organic synthesis, and playing an important role in drug development and preparation of fine chemicals.
    At the level of scientific research and exploration, its structure and properties have aroused the interest of many researchers. By studying its reaction mechanism and physicochemical properties, it helps to deepen the understanding of the characteristics of organic compounds, provide a basis for the construction of new theories and the development of new technologies, and promote the continuous progress of chemistry. In short, (methoxy) methylpyrazine plays an important role in many fields due to its various uses and has far-reaching impact.
    What are the physical properties of (Methoxy) methylpyrazine
    The physical properties of (methoxy) methylpyrazine are quite explainable. This substance is mostly liquid at room temperature. Looking at it, it is clear and transparent, like the quality of glaze, with a restrained luster. Smell it, it has a unique smell, and there is a slight fragrance in the fragrance, just like the smell of rare herbs in the mountains and forests, which attracts reverie.
    Its density is moderate, slightly lighter than water, and it can float slightly in water, like a light boat above a blue wave. In terms of solubility, it can be slightly soluble in water, just like a light rain merging into spring mud. Although it cannot be completely integrated, it can also partially intersect with each other. And in organic solvents, such as ethanol, ether, etc., its solubility is quite good, and it can be indistinguishable from each other, just like water emulsion blending, regardless of each other.
    Furthermore, the boiling point of (methoxy) methyl pyrazine also has its own characteristics. Under normal pressure, it needs to reach a specific temperature to boil. This temperature allows the force between molecules to be overcome, sublimating from liquid to gaseous state, just like phoenix nirvana, morphological change. Its melting point is also a key physical parameter. In a specific low temperature environment, it will solidify from liquid to solid state, just like lake water condenses into ice in winter, showing a different static beauty.
    (methoxy) methylpyrazine's dispersion force, dipole-dipole force and other intermolecular forces also have many effects on its physical properties. Dispersion force makes there is a weak and universal attraction between molecules, maintaining the aggregation state of molecules; dipole-dipole force exists due to the polarity of molecules, which has an effect on their solubility, boiling point and other properties, like a silk thread pulling a puppet, every move is controlled by it.
    What are the chemical properties of (Methoxy) methylpyrazine
    (Methoxy) methylpyrazine is one of the organic compounds. It has unique chemical properties and has specific uses in chemical and related fields.
    Looking at its physical properties, (methoxy) methylpyrazine is mostly liquid under normal conditions, with certain volatility and can emit a special odor. Its boiling point, melting point and other physical parameters vary depending on the characteristics of the substituents in the molecular structure.
    In terms of its chemical properties, the pyrazine ring in the compound is aromatic, and the introduction of methoxy and methyl groups makes it have specific reactivity. The oxygen atom in the methoxy group has a lone pair electron and can participate in a variety of nucleophilic reactions. In case of electrophilic reagents, the electron cloud distribution on the pyrazine ring will be affected by methoxy and methyl groups, which will change the reaction check point. Although the methyl group is relatively stable, under specific conditions, such as the action of strong oxidants, oxidation and other reactions can also occur.
    (methoxy) methyl pyrazine is often an important intermediate in the field of organic synthesis. It can be prepared by a variety of chemical reaction paths, and because of its unique chemical properties, it can react with many reagents to construct more complex organic molecular structures, laying the foundation for the preparation of various functional materials, drugs, etc.
    What is the production method of (Methoxy) methylpyrazine?
    The production method of (methoxy) methylpyrazine is particularly crucial. The method can be roughly divided into various ways.
    First, the corresponding pyrazine derivatives are started and prepared by specific etherification reaction. In a suitable reaction kettle, the selected pyrazine substrate is placed, and an appropriate amount of base is added as a catalyst, such as potassium carbonate. Then slowly add methoxy methylating reagents, such as chloromethyl ether. This process requires strict temperature control and is usually maintained at a moderate low temperature to prevent side reactions from clumping. After adding it dropwise, continue to stir for a period of time, and monitor the reaction process by high performance liquid chromatography until the substrate is fully converted. Then, the product is refined by extraction, column chromatography, etc., to obtain pure (methoxy) methylpyrazine. < Br >
    Second, this purpose can also be achieved by coupling reactions catalyzed by transition metals. Select halopyrazines, such as bromopyrazine, and methoxymethyl borate or similar reagents, and react in an organic solvent under the synergistic action of transition metal catalysts and ligands such as palladium and nickel. This reaction environment needs to be oxygen-free, and nitrogen or argon is often used to replace the air in the system. The reaction temperature depends on the selected reagent and catalyst, or it needs to be heated to a moderate temperature. After a certain period of time, the reaction is complete, and conventional separation and purification methods, such as distillation, recrystallization, etc., are used to obtain the target product.
    Third, biosynthesis methods have also emerged. Using the catalytic activity of specific microorganisms or enzymes, with suitable precursors as raw materials, under mild reaction conditions, the structure of (methoxy) methylpyrazine can be precisely constructed by enzymatic reaction in vivo. This approach is environmentally friendly and highly selective. However, it requires strict control of biological system culture and reaction conditions, and many parameters such as substrate concentration, pH, temperature, etc. need to be carefully regulated to ensure that the biocatalytic process is efficient and stable.
    What are the precautions for (Methoxy) methylpyrazine during use?
    (Methoxy) methylpyrazine is a special chemical substance, and many things need to be paid attention to when using it.
    First, this substance has a specific chemical activity, and it is necessary to strictly follow safety procedures when operating. Because of its active chemical nature, if the operation is not careful, or the chemical reaction is out of control, causing danger, such as explosion, fire and other disasters. Therefore, in the process of taking, mixing and reacting, when using suitable protective equipment, such as goggles, gloves, protective clothing, etc., to protect personal safety.
    Second, the smell of (methoxy) methylpyrazine is unique and strong. Its smell may cause irritation to human senses and even affect the respiratory system. Therefore, in the place of use, it is necessary to ensure smooth air circulation, or to set up effective ventilation devices to prevent odor accumulation and damage the health of the user.
    Third, its storage is also exquisite. It should be stored in a cool, dry and well-ventilated place, away from fire, heat and oxidants. Due to its nature or due to environmental factors, improper storage or deterioration will affect the use effect, or add safety hazards.
    Fourth, when using (methoxy) methylpyrazine, accurate measurement is the key. Because of its role in the reaction, it often depends on accurate dosage. Large amounts and small amounts can make the reaction results deviate from expectations, or cause the product to be impure, or make the reaction unable to achieve the desired effect. Therefore, accurate measuring instruments should be used and operated according to the established formula and process.
    Fifth, after use, properly dispose of the remaining materials and related equipment. Do not pour residual (methoxy) methylpyrazine at will to avoid polluting the environment. Related equipment should also be washed and stored for next use. In this way, the process of using (methoxy) methylpyrazine is guaranteed to be safe and effective, and to achieve the intended purpose.