Aminopyrazine
pyridine pyrrole pyrazine piperidine piperazine

AMINOPYRAZINE

    Specifications

    HS Code

    376882

    Name Aminopyrazine
    Molecular Formula C4H5N3
    Molar Mass 95.103 g/mol
    Appearance Solid
    Odor Typical amine - like odor
    Solubility In Water Slightly soluble
    Melting Point 68 - 72 °C
    Boiling Point 262 - 263 °C
    Density 1.224 g/cm³
    Flash Point 124.2 °C
    Pka Conjugate Acid 3.81

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    General Information
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    Frequently Asked Questions

    As a leading AMINOPYRAZINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of AMINOPYRAZINE?
    Aminopyrazine has a wide range of uses and is useful in various fields.
    First, in the field of medicine, aminopyrazine is a key raw material for the preparation of many drugs. Because of its specific chemical structure and activity, it can help synthesize drugs with antibacterial, antiviral, anti-tumor and other effects. Taking antibacterial drugs as an example, they can participate in the construction of drug molecular structures. By combining with key targets in the body of pathogens, they interfere with the normal physiological metabolism of pathogens and achieve the purpose of inhibiting or killing pathogens. This is of great significance in the fight against infectious diseases and escorts human health.
    Second, in the field of materials science, aminopyrazine also has extraordinary performance. It can be used to prepare high-performance polymer materials, which can be polymerized with other monomers to give the material unique properties. Such as improving the thermal stability and mechanical strength of the material. In terms of materials used in the aerospace field, polymer materials modified by aminopyrazine can better adapt to extreme environments and ensure the safe and reliable operation of aircraft components.
    Third, in agricultural chemistry, aminopyrazine can be used to develop new pesticides. Through rational design, it can be targeted to specific pests or pathogens, effectively control crop diseases and pests, and reduce the impact on the environment and non-target organisms. In this way, it can effectively ensure crop yield and quality, and promote sustainable agricultural development.
    Furthermore, aminopyrazine can also be seen in the field of analytical chemistry. It can be used as an analytical reagent for the detection and quantification of specific substances. Because it can react specifically with certain substances, accurate determination of target substances can be achieved by detecting reaction products or related signal changes. This is significant in environmental monitoring, food testing, etc., which can help to detect pollutants or harmful substances in time and ensure ecological environment and food safety.
    What are the physical properties of AMINOPYRAZINE?
    Aminopyrazine is one of the organic compounds. Its physical properties are unique.
    Looking at its appearance, it is often white to light yellow crystalline powder, delicate and uniform in quality, like fine sand, with a soft luster, just like the early morning glow sprinkling on it, exuding a quiet beauty.
    As for the melting point, the melting point of aminopyrazine is usually in a specific range, about 100-110 ° C. At this temperature limit, its solid state begins to gradually melt, just like ice and snow meeting warm sun, slowly turning into a flowing state, from hard to soft, which is the key node of its material form transformation.
    Solubility is also an important physical property. In water, aminopyrazine has a certain solubility, but it is not very soluble. Just like a wanderer in a foreign land, although it can hold the body, it is not completely at home. The polarity of water interacts with the molecular structure of aminopyrazine, resulting in a limited degree of solubility. However, in organic solvents, such as ethanol and acetone, its solubility is significantly enhanced, just like a wanderer to a familiar place, it can be easily integrated. In ethanol, its molecules and ethanol molecules intertwine and disperse uniformly to form a uniform system.
    Furthermore, the density of aminopyrazine is also a specific value, about 1.3 g/cm ³. This density value makes it unique in weight characteristics among various substances. If placed on the balance, it can be compared with other substances of the same volume.
    The vapor pressure of aminopyrazine is quite low, which means that under normal temperature and pressure, its volatilization tendency is not very significant. Like a calm person, it does not easily show signs, is relatively stable in the environment, does not easily escape into the air, and maintains its own existence form.
    Its refractive index also has a unique value. When light passes through aminopyrazine, the path of light is bent by it, showing a specific angle. The value of this angle is the refractive index, which is a characterization of its optical properties and reflects the unique way its internal molecular structure acts on light.
    What are the chemical properties of AMINOPYRAZINE?
    Aminopyrazine is one of the genera of organic compounds. It is basic and can form salts with acids because the molecule contains nitrogen atoms. This is because the lone pair of electrons on the nitrogen atom can accept protons.
    In terms of chemical reactivity, the amino group of aminopyrazine can participate in many reactions. Such as acylation, the hydrogen of the amino group can be replaced by an acyl group to obtain amide derivatives. This reaction usually uses acyl halide or acid anhydride as acylation reagents and can occur under suitable conditions.
    And its pyrazine ring also has special reactivity. Pyrazine ring is aromatic and can undergo electrophilic substitution reaction. However, due to the high electronegativity of the nitrogen atom on the ring, the density of the ring electron cloud decreases, so the electrophilic substitution reaction activity is lower than that of the benzene ring. Electrophilic reagents often attack the position where the electron cloud density on the ring is relatively high.
    Furthermore, aminopyrazine can participate in the coordination reaction. Its nitrogen atom can provide lone pair electrons to coordinate with metal ions to form metal complexes. Such complexes have potential applications in catalysis, materials science and other fields.
    In terms of physical properties, aminopyrazine is mostly solid, with a certain melting point and boiling point. Its solubility varies according to the specific structure and substituents, and some are soluble in water or common organic solvents such as ethanol, dichloromethane, etc. Due to its unique chemical properties, aminopyrazine has important uses in many fields such as medicinal chemistry, material chemistry, and organic synthesis. It is an important compound in chemical research and industrial production.
    What are the precautions of AMINOPYRAZINE in the production process?
    Aminopyrazine is an important chemical substance, and various precautions are essential during the production process.
    First, it is related to safety protection. Aminopyrazine may be toxic and irritating, and operators must strictly follow safety procedures. During operation, appropriate protective equipment should be worn, such as protective clothing, gloves, goggles and gas masks, to prevent skin contact, inhalation or accidental ingestion. And the workplace should be well ventilated, equipped with complete ventilation facilities, and harmful gases should be discharged in time to prevent the accumulation of hazards.
    Second, material management cannot be ignored. Storage of aminopyrazine should be placed in a cool, dry and ventilated place, away from fire and heat sources. It needs to be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to prevent chemical reactions. When taking materials, they should be accurately weighed and follow the formula requirements to avoid material waste or improper proportions affecting product quality.
    Third, production process control is extremely critical. Strictly control the reaction conditions, such as temperature, pressure, reaction time and the proportion of reactants. Different reaction conditions or product purity and yield differences. For example, if the reaction temperature is too high, or side reactions increase, the product purity will decrease; if the reaction time is insufficient, the reaction may be incomplete and the yield will decrease. Therefore, it is necessary to monitor and adjust the reaction conditions in real time with the help of accurate equipment to ensure the stability of the production process and the uniformity of product quality.
    Fourth, equipment maintenance and cleaning should not be underestimated. Regular inspection, maintenance and cleaning of production equipment to ensure normal operation of equipment. If the equipment fails or causes production accidents, it will affect product quality. Cleaning equipment can prevent impurities from remaining and avoid interference in subsequent production.
    Fifth, personnel training is also an important part. For personnel involved in the production of aminopyrazine, comprehensive training should be carried out to make them familiar with the production process, safety knowledge and operation skills. Only well-trained personnel can effectively deal with various problems in the production process and ensure production safety and product quality.
    What are the possible reactions of AMINOPYRAZINE with other substances?
    Aminopyrazine is an organic compound. It is active and can react with many substances.
    When it meets with acids, the amino groups in aminopyrazine are basic and can combine with acids to form salts. For example, when reacted with hydrochloric acid, the amino group obtains protons to form positively charged ammonium ions, which combine with chloride ions to obtain aminopyrazine hydrochloride. This salt has good solubility in water and has different chemical properties than the original aminopyrazine.
    In case of oxidants, aminopyrazine can be oxidized. Amino or pyrazine rings may be oxidized, causing structural changes and forming new oxidation products. If treated with a strong oxidizing agent, the pyrazine ring or ring opening, or the amino group is oxidized to an oxygen-containing functional group such as nitro, the chemical activity and use of the product are also different.
    In the nucleophilic substitution reaction, if there is a suitable nucleophilic reagent, some atoms on the pyrazine ring can be replaced. The edge pyrazine ring has a certain electron cloud distribution, and the specific position can be attacked by nucleophilic reagents. Halogenated hydrocarbons are used as nucleophilic reagents. Under suitable conditions, halogenated atoms can replace hydrogen atoms on the pyrazine ring to obtain halogenated aminopyrazine derivatives. In the field of organic synthesis, such derivatives are important intermediates and can be further reacted to produce a variety of complex compounds.
    In case of metal ions, the nitrogen atom in aminopyrazine has a lone pair of electrons, which can be used as a ligand to complex with metal ions. Stable metal complexes are formed by the coordination of nitrogen atoms and metal ions. This complex has a wide range of uses in the field of catalysis. It can be used as a catalyst to catalyze specific chemical reactions, changing the reaction rate and selectivity.
    In the alkylation reaction, aminopyrazine can react with alkylation reagents. Alkyl groups can be introduced into aminopyrazine molecules to change the structure and properties of the product. The types of alkylation reagents and reaction conditions are different, and the products are different. They can be alkylated on amino groups or alkylated at specific positions in pyrazine rings. The new products have potential application value in pharmaceutical chemistry, materials science and other fields.