6 5 Chloro 2 Pyridinyl 7 Oxo 6 7 Dihydro 5h Pyrrolo 3 4 B Pyrazin 5 Yl Phenyl Carbonate
pyridine pyrrole pyrazine piperidine piperazine

6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate

    Specifications

    HS Code

    970273

    Chemical Formula C18H10ClN3O4
    Molecular Weight 367.74
    Appearance Solid (predicted)
    Boiling Point 614.4°C at 760 mmHg (predicted)
    Melting Point 183 - 185°C
    Logp 3.29 (predicted)
    Solubility Soluble in DMSO, DMF (predicted)
    Pka 12.61±0.70 (predicted)
    Density 1.58 g/cm³ (predicted)
    Vapor Pressure 3.04E-15 mmHg at 25°C (predicted)

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    Frequently Asked Questions

    As a leading 6-(5-Chloro-2-pyridinyl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl phenyl carbonate supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 6- (5-chloro-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyrrole [3,4-b] pyrazine-5-yl, phenyl carbonate?
    My question is about the chemical structure of 6- (5-cyano-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyridyl [3,4-b] pyridyl-5-yl + benzyl carbonate. The structure of this compound is slightly complicated, let me elaborate.
    Its core structure is pyridyl [3,4-b] pyridine, which is formed by fusing a pyridine ring with another pyridine ring to form a unique dicyclic structure. In this fused ring system, a substituent is connected at the 6th position, namely (5-cyano-2-pyridyl). This substituent is a pyridine ring connected to the main structure at the 2nd position, and the 5th position has a cyano (-CN) group. The
    7 position is the oxygen generation, that is, the carbonyl (C = O) structure is formed. 6,7-dihydro indicates that the fused ring system is hydrogenated at the double bond at the 6th and 7th positions, showing a partially saturated state. 5H indicates that the structure exists in the form of a five-membered ring in the whole molecule.
    The 5-group is connected to benzyl carbonate, and benzyl (C H CH ² -) is connected to carbonate (-O - CO - O -) through oxygen atoms, forming one part of this complex molecular structure.
    The structure of this compound fuses a variety of functional groups and rings, and the interaction of each part gives it unique chemical and physical properties, which may be of great significance in the fields of organic synthesis and medicinal chemistry.
    What are the physical properties of 6- (5-chloro-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyrrole [3,4-b] pyrazine-5-yl, phenyl carbonate
    #On the physical properties of sodium silicate
    Sodium silicate, also known as capsuline, is a commonly used inorganic compound. It is widely used in industry and daily life. This substance has many unique physical properties and has far-reaching impact in many fields.
    ##Morphology and solubility
    Sodium silicate is mostly a colorless transparent or slightly colored viscous liquid under normal conditions, and some are also in the form of solid powder. The solubility in water is quite considerable, and the degree of solubility is closely related to the modulus. The modulus is the ratio of the amount of silica to sodium oxide. The lower the modulus, the better the solubility in water. For example, sodium silicate with low modulus can be easily dissolved in water to form a uniform solution; while for high modulus, it is relatively difficult to dissolve and requires a higher temperature and a longer time to dissolve.
    ##Viscosity and adhesion
    Sodium silicate solution has significant viscosity, which makes it have good bonding properties. Because it can form a strong adhesive force on the surface of different materials, it is often used as a binder. In the construction field, it is used to bond bricks, stones and other materials to enhance the stability of structures; in the foundry industry, it is used to bond sand grains to make sand molds to ensure the accuracy and quality of castings. < Br >
    ##Density and Hardness
    The density of solid sodium silicate is relatively large, generally around 2.4 grams/cubic centimeter. This higher density gives it a certain sense of weight. After specific processing, sodium silicate can form a solid material with a certain hardness. This hardness makes it suitable for some wear-resistant applications, such as the manufacture of abrasives, ceramics, etc., which can improve the wear resistance of products.
    ##Melting Point and Boiling Point
    The melting point of sodium silicate is quite high, usually around 1088 ° C. Such a high melting point allows it to maintain solid state stability in high temperature environments. Regarding the boiling point, because sodium silicate will decompose first during heating, there is no clear boiling point. This property allows it to withstand high temperatures in high-temperature industrial production, such as refractory manufacturing, without melting, ensuring the safety and stability of the production process.
    The many physical properties of sodium silicate make it play an indispensable role in many fields such as industry, construction, materials, etc., and have a profound impact on human production and life.
    What is the main use of 6- (5-chloro-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyrrole [3,4-b] pyrazine-5-yl, phenyl carbonate?
    #The wonders of lycorine
    Lycorine and its related derivatives, such as 6- (5-bromo-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyridyl [3,4-b] pyridyl-5-one, etc., have important uses in many fields.
    Lycorine plays a significant role in the field of medicine. First, it has certain anti-tumor activity. Studies have found that lycorine can inhibit the proliferation and growth of tumor cells through various mechanisms, such as interfering with the mitotic process of tumor cells, making them unable to carry out cell division normally, thus inhibiting the development of tumors. Second, lycorine also shows potential in the treatment of neurological diseases. It can regulate the release and transmission of neurotransmitters, and is expected to play a role in improving cognitive function in neurodegenerative diseases such as Alzheimer's disease. Third, lycorine also has certain anti-inflammatory properties, which can reduce inflammation and relieve various symptoms caused by inflammation.
    In the field of agriculture, lycorine also contributes. Due to its repellent or inhibitory effect on some pests, it can be used as a natural biopesticide raw material. Compared with chemical pesticides, biopesticides developed on the basis of lycorine are more environmentally friendly, less likely to cause environmental pollution, and can reduce the risk of pests developing resistance to chemical pesticides, which is conducive to the sustainable development of agriculture.
    In addition, lycorine can be used as an important intermediate in the field of organic synthesis. Due to its unique chemical structure, it can construct a variety of organic compounds with special functions through a series of chemical reactions, providing a basis for the research and development of new materials, drugs, etc.
    To sum up, lycorine and its related derivatives have non-negligible uses in many fields such as medicine, agriculture, and organic synthesis, and are of great significance in promoting the development of various fields.
    What are the synthesis methods of 6- (5-chloro-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyrrole [3,4-b] pyrazine-5-yl, phenyl carbonate
    To prepare 6- (5-cyano-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyridyl [3,4-b] pyridyl-5-yl + benzyl carbonate, the method is as follows:
    Take an appropriate amount of starting material first, and then obtain this product through clever reaction steps. The groups on the pyridine ring can be converted first with specific reagents. In a suitable reaction vessel, control temperature, pressure and other conditions to fully react the reactants. < Br >
    If you want to introduce a cyanide group, you can find a suitable cyanide reagent and put it in an appropriate reaction medium to undergo nucleophilic substitution or other related reactions with the substrate to accurately place the cyanide group at the 5-position. For the modification of the 2-position on the pyridine ring, you also need to select the appropriate reagent and operate according to a reasonable reaction sequence.
    As for the construction of 7-oxo-6,7-dihydro-5H-pyrido [3,4-b] pyridine-5-base parts, or through multi-step reactions, with specific catalysts or conditions, each group is gradually connected and cyclized to achieve the desired structure.
    Finally, when adding the benzyl carbonate part, the appropriate reaction path should be selected according to its reactivity to ensure that it is accurately connected to the target position. The whole synthesis process is like a delicate chemical dance, each step needs to be closely connected, and the conditions must be precisely controlled in order to obtain 6- (5-cyano-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyridyl [3,4-b] pyridyl-5-yl + benzyl carbonate efficiently and with high purity.
    What are the precautions for the use of 6- (5-chloro-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyrrole [3,4-b] pyrazine-5-yl, phenyl carbonate?
    In the process of using 6- (5-ammonia-2-pyridyl) -7-oxo-6,7-dihydro-5H-pyridyl [3,4-b] pyridyl-5-yl + benzyl carbonate, the following matters should be noted:
    First, it is related to the storage of the substance. This compound should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Because it may be sensitive to heat, it is easy to decompose or deteriorate due to heat, which affects its performance and quality. At the same time, avoid storing with strong oxidants, strong acids, strong alkalis and other substances to prevent chemical reactions from occurring and causing dangerous conditions.
    Second, it involves the operation process. During the operation, be sure to wear appropriate protective equipment, such as protective gloves, protective glasses and laboratory clothes. Because the compound may have irritating effects on the skin, eyes and respiratory tract, direct contact can easily cause damage to the human body. If you accidentally come into contact with the skin or eyes, you should immediately rinse with plenty of water and seek medical treatment in time. During the experimental operation, it should be carried out in the fume hood to ensure the air circulation of the operating environment and prevent the accumulation of harmful gases and endanger the health of the operator.
    Third, about waste disposal. Waste generated after use must not be discarded at will. It needs to be sorted and collected in accordance with relevant regulations and delivered to a treatment agency with professional qualifications for proper disposal. This is because the compound may have certain toxicity or environmental hazards. If it is not handled properly, it will cause pollution to the environment.
    Fourth, for the use of dose. It should be taken accurately according to the experimental or production requirements to avoid waste caused by excessive use, and also to prevent inaccurate experimental results or abnormal production process due to dose deviation. After taking it, the container should be sealed in time to prevent the substance from getting damp, oxidizing or reacting with other substances.