5 Methylpyrazine 2 Carbonitrile
pyridine pyrrole pyrazine piperidine piperazine

5-methylpyrazine-2-carbonitrile

    Specifications

    HS Code

    327425

    Name 5-methylpyrazine-2-carbonitrile
    Molecular Formula C6H5N3
    Molecular Weight 119.12 g/mol
    Appearance Solid (usually)
    Physical State At Room Temp Solid
    Melting Point 113 - 115 °C
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Color Off - white to light yellow
    Chemical Stability Stable under normal conditions, but can react with strong acids or bases

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    Frequently Asked Questions

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    What is the chemistry of 5-methylpyrazine-2-carbonitrile?
    5-Methylpyrazine-2-formonitrile is an organic compound. Its properties have special chemical characterization. In the structure of this compound, the pyrazine ring is based, and the methyl group is connected at the 5th position, and the formonitrile group is connected at the 2nd position. This unique structure gives it specific chemical properties.
    In terms of its physical rationality, 5-methylpyrazine-2-formonitrile is usually in a solid or liquid state at room temperature, but the exact state varies according to its purity and external conditions. Its melting point, boiling point and other physical parameters depend on the interaction between molecules. The pyrazine ring has a conjugated system, which increases the stability of the molecule, so that its melting boiling point is different from that of ordinary chain compounds.
    As for chemical properties, methanitrile groups have higher reactivity. Methanitrile groups can be hydrolyzed, and under the catalysis of acids or bases, they can be converted into carboxyl groups to produce 5-methylpyrazine-2-carboxylic acids. This hydrolysis reaction is catalyzed by bases at a rate or faster, because the base can react with the generated acid, pushing the equilibrium to the right.
    In addition, methanitrile groups can be reduced. With an appropriate reducing agent, such as lithium aluminum hydride, it can be reduced to an amine group to obtain 5-methylpyrazine-2-methylamine. This reduction reaction is often a key step in organic synthesis, which can introduce new functional groups and expand the application of compounds.
    Methyl also participates in many reactions. Under appropriate conditions, methyl can be halogenated, such as with halogens under the action of light or catalyst, to form halogenated methyl pyrazine derivatives. This halogenated product can be used as an intermediate for the construction of more complex organic molecules, because halogen atoms are easily replaced by other functional groups.
    5-methylpyrazine-2-formonitrile has an important position in organic synthesis, pharmaceutical chemistry and other fields due to its unique chemical properties. It can be used as a key intermediate to provide a basis for the creation of new compounds and drugs.
    What are the main uses of 5-methylpyrazine-2-carbonitrile?
    5-Methylpyrazine-2-formonitrile, an organic compound, has important uses in many fields.
    First, in the field of pharmaceutical chemistry, it is often used as a key intermediate. Compounds with specific biological activities can be derived through a series of chemical reactions. In the process of many drug development, pyrazine and nitrile groups in its structure can participate in the reaction, helping to construct complex and pharmacologically active molecular structures, laying the foundation for the creation of new drugs.
    Second, in the field of materials science, it can be used as a raw material for the synthesis of special functional materials. Its unique chemical structure endows materials with specific properties. For example, some materials with specific electrical and optical properties can be reasonably designed and synthesized to be applied to electronic devices, optical sensors, etc.
    Third, it is also involved in the fragrance industry. Because it can participate in specific reactions to generate substances with unique odors, it can be used as a raw material or auxiliary agent to add unique aroma components to fragrance formulations.
    Fourth, in the field of organic synthesis, as a key building block, with its functional group characteristics, nucleophilic substitution, addition and other reactions occur with other organic reagents to achieve the construction of complex organic molecules and help the development of organic synthesis chemistry.
    What is 5-methylpyrazine-2-carbonitrile synthesis method?
    The synthesis of 5-methylpyrazine-2-formonitrile is a matter of great importance to chemical processes. To obtain this substance, common methods include using compounds containing pyrazine structures as starting materials and various chemical reactions.
    First, pyrazine derivatives with appropriate substituents can be selected, such as 5-methylpyrazine-2-carboxylic acid and its esters, which can be used as starting materials. If 5-methylpyrazine-2-carboxylic acid is used as the starting point, it can be converted into acyl chloride first, often with reagents such as sulfoxide chloride. When the carboxylic acid encounters thionyl chloride, the carboxyl group is converted into an acyl chloride to give 5-methylpyrazine-2-formyl chloride.
    Then, the acyl chloride interacts with the cyanide reagent. Common cyanide reagents such as alkali metal cyanides such as sodium cyanide and potassium cyanide. In a suitable solvent, such as dichloromethane, N, N-dimethylformamide, etc., the acyl chloride and cyanide undergo nucleophilic substitution reaction, and the acyl chloride is replaced by a cyanide group to obtain 5-methylpyrazine-2-formonitrile. < Br >
    Or starting from 5-methylpyrazine-2-carboxylic acid ester, first treat with alkali to hydrolyze the ester group into a carboxyl group, and then use the above method of making formonitrile from carboxylic acid to achieve the goal. The base can be selected from sodium hydroxide, potassium hydroxide, etc. After hydrolysis is completed, it is converted into an acyl chloride according to the previous method, and then reacted with a cyanide reagent.
    Another way can be synthesized by constructing a pyrazine ring. For example, under certain conditions, under appropriate nitrogen-containing and carbonyl-containing compounds, a pyrazine ring is formed by cyclization reaction, and methyl and cyano are introduced at the same time. However, this way is more complicated, and the reaction conditions and the proportion of reagents need to be carefully controlled to ensure the purity and yield of the In short, there are various methods for the synthesis of 5-methylpyrazine-2-formonitrile, and the best method should be selected according to many factors such as raw material availability, cost, reaction conditions and product purity.
    What is the market outlook for 5-methylpyrazine-2-carbonitrile?
    5-Methylpyrazine-2-formonitrile, the market prospect of this product in today's world is quite promising. It is widely used in the chemical industry.
    In the way of pharmaceutical synthesis, 5-methylpyrazine-2-formonitrile is a key intermediate. Today, the pharmaceutical industry is booming, and the demand for various specific drugs is increasing day by day. The research and development of many new drugs rely on this compound as a base to form its complex structure. Therefore, with the deepening of pharmaceutical research and development, its market demand will surely rise.
    Furthermore, in the pesticide manufacturing industry, 5-methylpyrazine-2-formonitrile also has a place. Nowadays, agriculture pursues highly efficient and environmentally friendly pesticides. This compound can provide a unique chemical structure for the synthesis of new pesticides, which can help them improve their efficacy and reduce their harm to the environment. Therefore, with the advancement of agricultural modernization, the demand for pesticides in the field of pesticides is also expected to increase.
    As for materials science, its potential applications cannot be underestimated. With the development of science and technology, new materials emerge in an endless stream. 5-methylpyrazine-2-formonitrile may be able to participate in the creation of new functional materials with its special chemical properties. Although it is not widely used in the field of materials at present, with time, with the advancement of research, a new world may be opened up.
    However, although the market prospect is good, it also faces challenges. The production process needs to be continuously optimized to reduce costs and improve quality in order to come out on top in the market competition. And the market situation is changing, and the competition among peers is fierce. It is necessary to gain insight into market dynamics and adjust strategies in time to seize the opportunity and enjoy the market dividend of 5-methylpyrazine-2-formonitrile.
    5-methylpyrazine-2-carbonitrile what are the precautions during use
    5-Methylpyrazine-2-formonitrile is an organic compound. During use, the following points should be paid attention to:
    First, safety protection is the key. This compound may be toxic and irritating. When operating, be sure to wear suitable protective equipment, such as gloves, goggles and protective clothing, to prevent it from coming into direct contact with the skin and eyes, and to avoid inhaling its dust or vapor. It is recommended to operate in a well-ventilated place or in a fume hood.
    Second, storage is also particular. Store it in a cool, dry and ventilated place, away from fire, heat sources, and direct sunlight. At the same time, it should be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent dangerous chemical reactions.
    Third, the chemical properties should not be underestimated. When participating in various chemical reactions, it is necessary to fully understand their reaction characteristics and conditions. Because its structure contains nitrile groups and pyrazine rings, it will exhibit specific chemical activities. In different reaction systems, factors such as reaction temperature, time and proportion of reactants must be strictly controlled to ensure that the reaction proceeds in the expected direction and obtain ideal products.
    Fourth, waste treatment needs compliance. Waste generated during use, including expired or remaining 5-methylpyrazine-2-formonitrile, should be properly disposed of in accordance with relevant environmental regulations and should not be discarded at will to avoid pollution to the environment. Generally speaking, it needs to be disposed of harmlessly by a professional qualified treatment agency.