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What are the main uses of 5-methyl-pyrazinecarboxylic acid?
5-Methyl-pyrazine carboxylic acid, which has a wide range of uses. In the field of medicine, it is an important organic synthesis intermediate and can be used to create a variety of drugs. The structure of Geinpyrazine has unique activities in many drug molecules. 5-methyl-pyrazine carboxylic acid can be chemically modified and reacted to introduce into the molecular structure of drugs, giving drugs specific physiological activities, such as antibacterial, anti-inflammatory and anti-tumor effects.
In the chemical industry, it also has important functions in the preparation of functional materials. It can be polymerized or reacted with other compounds to prepare polymer materials with special properties, such as some polymers with good thermal stability and mechanical properties, which may be used in high-end fields such as aerospace and electronics.
Furthermore, in the field of food additives, it may play a unique role. Due to its structural characteristics, it may produce unique flavors or aromas. After being suitable for current treatment and research, it may be used as a new type of food flavor additive to enhance food flavor and enhance food attractiveness. In short, 5-methyl-pyrazine carboxylic acid has shown wide application potential in many fields such as medicine, chemical industry, and food due to its unique chemical structure.
What are the physical properties of 5-methyl-pyrazinecarboxylic acid?
5-Methyl-pyrazine carboxylic acid, which is usually a crystalline powder with a white color and a specific odor. The melting point of this substance is very critical. The melting point is about 188-192 ° C. At this temperature, it gradually melts from a solid state to a liquid state. This process requires absorption of heat to overcome lattice energy. The boiling point is affected by environmental pressure. At normal pressure, it reaches about 350 ° C. When the molecule is energized enough to escape from the liquid surface and become a gas state. < Br >
Its solubility also has characteristics, and it has a certain solubility in water. Because the molecule contains carboxyl groups, it can form hydrogen bonds with water molecules to improve solubility; in organic solvents, such as ethanol and acetone, the solubility is good. According to the principle of similar phase solubility, its organic structure is compatible with the organic solvent.
In terms of density, relative to water, it is about 1.3-1.4 g/cm ³, which means that under the same volume, its mass is heavier than water. In terms of stability, under normal temperature and pressure and general storage conditions, the properties are relatively stable, but when encountering strong oxidizing agents, strong acids and bases, chemical reactions may occur and cause structural changes. It has a certain tolerance to light and heat, but prolonged exposure to strong light or high-temperature environments may cause it to decompose and deteriorate.
What are the chemical properties of 5-methyl-pyrazinecarboxylic acid?
5-Methyl-pyrazine carboxylic acid, this is an organic compound. Its properties have a variety of characteristics, let me come one by one.
Looking at its physical properties, under normal conditions, it is mostly in the shape of a solid state, but it also varies depending on the temperature and humidity of the environment. Its color is often close to white or off-white, and its shape is crystalline, and the texture is quite delicate. Its taste is specific, although not pungent, it is also unique. Its solubility in water is not very high, only slightly soluble in water, but in some organic solvents, such as ethanol and acetone, it is slightly soluble.
When it comes to chemical properties, 5-methyl-pyrazine carboxylic acid is acidic. This is because its molecular structure contains a carboxyl group, which can release hydrogen ions under suitable conditions, so it is acidic. It can also neutralize with bases to generate corresponding salts and water. For example, by reacting with sodium hydroxide, 5-methyl-pyrazine sodium carboxylate and water can be formed.
Furthermore, the pyrazine ring and methyl group in the molecule make it have a certain reactivity. The nitrogen atom on the pyrazine ring has a lone pair of electrons and can participate in many nucleophilic substitution reactions. The methyl group can be converted into other functional groups due to reactions such as oxidation. For example, under the action of an appropriate oxidizing agent, the methyl group can be oxidized to a carboxylic group, thereby forming dicarboxylic acids.
In addition, 5-methyl-pyrazine carboxylic acid can participate in the esterification reaction. When combined with alcohols, under the condition of acid catalysis, the carboxyl group can react with the alcohol hydroxyl group to form esters and water. This ester product may have a unique aroma and may have applications in the fields of fragrances.
In summary, 5-methyl-pyrazine carboxylic acid has potential uses and values in many fields such as organic synthesis, drug development, and fragrance preparation due to its unique physical and chemical properties.
What are the synthetic methods of 5-methyl-pyrazinecarboxylic acid?
The synthesis method of 5-methyl-pyrazine carboxylic acid has been explored throughout the ages. The method has a variety of paths to be found, depending on the raw materials and reaction conditions, and each has its own advantages.
First, it can be prepared by specific oxidation steps starting from the corresponding compounds containing methyl and pyrazine structures. For example, starting with a methylpyrazine substance, choose a suitable oxidant, such as a reagent with strong oxidizing properties, and carefully control the reaction process at a specific temperature, pressure and reaction time. This oxidant needs to be carefully selected according to the characteristics of the substrate, not only to seek oxidation effect, but also to prevent excessive oxidation from damaging the product. The regulation of the reaction temperature is also the key. If it is too high, it is easy to cause side reactions, if it is too low, the reaction will be slow and the yield will be poor.
Second, it can also be achieved by methylation reaction based on pyrazine carboxylic acid. Among these, it is extremely important to choose the appropriate methylation reagent, such as a classic methylation reagent, with the appropriate catalyst, and react in a suitable solvent environment. The solvent needs to have good solubility to the reactants and reagents without interfering with the reaction. The catalyst can accelerate the reaction rate, but its dosage and activity need to be precisely controlled, otherwise the purity and yield of the product will be affected.
Third, there is a strategy to synthesize the pyrazine ring by introducing methyl and carboxyl groups at the same time. This path requires clever design of reaction steps, using raw materials containing specific functional groups, and one or more steps of cyclization reaction to construct the target structure. In this process, precise control of the ratio of raw materials, reaction sequence, and reaction conditions is crucial to successfully obtaining the product and improving the yield and purity.
All these synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively consider the availability of raw materials, cost, difficulty of reaction operation, and product quality, and make careful choices to achieve the ideal synthesis effect.
What is the price range of 5-methyl-pyrazinecarboxylic acid in the market?
The price of 5-methyl-pyrazine carboxylic acid in the market varies depending on the purity of the product, the situation of supply, and the amount purchased. If at the time of "Tiangong Kaiwu", although there is no such certainty, it can be deduced.
At present, for ordinary purity, the price per gram may be around tens to hundreds of yuan. If it is a high-purity product, it is used in the field of fine, such as medical research and high-quality trial drugs, and the price is high, or more than hundreds of yuan per gram.
If you buy it in bulk, the price may drop due to the game between supply and demand. Large enterprises ask for a whole ton, and the price may fall to thousands of yuan per kilogram; small enterprises ask for a small amount, and the price per kilogram may be more than 10,000 yuan.
The market is turbulent, and the price of raw materials, the technology of production, and the prosperity and weakness of demand all move their prices. If raw materials are easy to obtain and the technology of production is advanced, the price may drop; if they need to increase sharply and the supply is insufficient, the price may rise. The price is variable, about tens of yuan per gram to tens of thousands of yuan per kilogram.