5 Chloropyrazine 2 Carboxlic Acid
pyridine pyrrole pyrazine piperidine piperazine

5-chloropyrazine-2-carboxlic acid

    Specifications

    HS Code

    140191

    Name 5-chloropyrazine-2-carboxlic acid
    Chemical Formula C5H3ClN2O2
    Molar Mass 158.54 g/mol
    Appearance Solid (likely white or off - white powder)
    Solubility In Water Limited solubility
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 5-chloropyrazine-2-carboxlic acid supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemistry of 5-chloropyrazine-2-carboxlic acid?
    5-Chloropyrazine-2-carboxylic acid, an organic compound. Its appearance is often white to pale yellow solid powder.
    In terms of physical properties, the melting point of this substance is quite high, which is due to the existence of strong forces between molecules, such as hydrogen bonds and van der Waals forces, which make the molecules closely arranged, requiring a lot of energy to break the lattice and cause it to melt.
    Its solubility also has characteristics, and it is not good in polar solvents such as water. Although the molecule contains carboxyl groups that can form hydrogen bonds with water, the presence of chlorine atoms and pyrazine rings results in the limited polarity of the molecule and the weak interaction with water. However, in some polar organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), the solubility is relatively good, because these organic solvents can form a suitable interaction with 5-chloropyrazine-2-carboxylic acid molecules to help them disperse and dissolve.
    In terms of chemical properties, carboxyl groups make it acidic, which can neutralize with bases to form corresponding carboxylic salts. For example, when reacting with sodium hydroxide, the hydrogen atom of the carboxyl group is replaced by sodium ions to form a sodium salt of 5-chloropyrazine-2-carboxylate. At the same time, chlorine atoms act as active substituents and can participate in nucleophilic substitution reactions. Under appropriate nucleophilic reagents and reaction conditions, chlorine atoms can be replaced by other groups to derive compounds with diverse structures, which are widely used in the field of organic synthesis and can be used to construct more complex molecular structures for the creation of drugs, materials, and other organic compounds.
    What are the main uses of 5-chloropyrazine-2-carboxlic acid?
    5-Chloropyrazine-2-carboxylic acid (5-chloropyrazine-2-carboxylic acid) has its uses in various fields such as chemical industry and medicine.
    In the field of chemical industry, it can be a key raw material for organic synthesis. With it as a starting material, various organic compounds with special structures and properties can be prepared through various chemical reactions. For example, through condensation reaction with specific reagents, more complex heterocyclic systems can be constructed, providing a basis for the research and development of new materials.
    In the field of medicine, it is widely used. It can be used as a drug intermediate to help synthesize a variety of drugs. Due to the characteristics of its molecular structure, it can endow the synthesized drugs with specific biological activities. or can participate in the preparation of antibacterial drugs, by combining with specific targets in bacteria, interfering with their normal physiological metabolism to achieve antibacterial effect; or play a role in the development of anti-tumor drugs, inhibiting the growth of tumors by affecting the proliferation and differentiation of tumor cells.
    Or play a role in the creation of agricultural chemicals. It can be chemically modified to develop new pesticides with insecticidal, bactericidal or herbicidal effects, contributing to the growth of crops and the improvement of yield.
    All of these, 5-chloropyrazine-2-carboxylic acid has shown its important value in many fields, and it is a widely used chemical substance.
    What are the synthetic methods of 5-chloropyrazine-2-carboxlic acid?
    The synthesis method of 5-chloropyrazine-2-carboxylic acid has been investigated by many parties throughout the ages. One method is to use pyrazine-2-carboxylic acid as the initial raw material and first undergo halogenation reaction. In a suitable reaction vessel, pyrazine-2-carboxylic acid is added, and an appropriate amount of halogenating agent, such as chlorination agent, is mixed with chlorine atoms to replace hydrogen atoms at a specific position on the pyrazine ring at a specific temperature, pressure and catalyst to generate 5-chloropyrazine-2-carboxylic acid. In this process, temperature control is crucial. If it is too high, side reactions will easily occur, and if it is too low, the reaction rate will be slow.
    Another way is to use compounds containing chlorine and pyrazine structures as starting materials and transform them into functional groups. Under specific reaction conditions, the starting compound is gradually transformed through a series of chemical reactions, such as oxidation, reduction, substitution, etc., and finally 5-chloropyrazine-2-carboxylic acid is obtained. In the meantime, the conditions of each step of the reaction need to be precisely regulated, and the type and dosage of the reagents used have a great influence on the purity and yield of the product.
    Furthermore, from the basic organic raw materials, the pyrazine ring can be constructed by multi-step reaction and chlorine atoms and carboxyl groups can be introduced. First, an appropriate small organic molecule, such as a compound containing nitrogen and carbon, is formed by condensation, cyclization and other reactions to form a pyrazine ring structure. Then, at a suitable stage, chlorine atoms and carboxyl groups are introduced at specific positions by means of halogenation, carboxylation, etc., to obtain 5-chloropyrazine-2-carboxylic acid. Although this synthesis path is complicated, the reaction steps and conditions can be flexibly adjusted according to the characteristics of the desired product to achieve the desired synthesis effect.
    What is the market price of 5-chloropyrazine-2-carboxlic acid?
    5-Chloropyrazine-2-carboxylic acid, the price of this product in the market is difficult to determine. The price of this product often varies due to various reasons, and it cannot be covered in one word.
    First, it is related to the preparation method. If the preparation process is sophisticated and convenient, and the raw materials are easy to find and cheap, the cost of production is low, and the price in the market may not be high. On the contrary, if the preparation process is complicated, rare raw materials are required, and a lot of material resources and manpower are consumed, the price will be high.
    Second, it depends on the demand. In the pharmaceutical, chemical and other industries, if there is a high demand for this product, the supply will exceed the demand, and the price will rise; if the demand is low, the supply will exceed the demand, and the price will drop automatically.
    Third, market competition also has an impact. If there are many merchants in this product, competing for profits with each other, in order to compete for customers, the price may be reduced to Bo; if there are few players, and they are almost monopolized, the price will be controlled by them, or the price will be high.
    Fourth, regional differences are also related. In different places, the price may be different due to the difference in transportation costs, taxes, etc. In distant places, the price is often higher than near the place of origin.
    In the past, at some time or place, due to the improvement of the preparation process, the cost was greatly reduced, and the price plummeted, which shocked the market. Later, due to the development of new drugs by a pharmaceutical company, the demand for this product increased sharply, and the price rose again.
    In short, in order to know the exact market price of 5-chloropyrazine-2-carboxylic acid, it is necessary to carefully examine the current preparation method, market demand, competition situation and regional differences and many other factors, and comprehensively weigh them to obtain a more accurate price.
    What are the precautions for 5-chloropyrazine-2-carboxlic acid in storage and transportation?
    5-Chloropyrazine-2-carboxylic acid is an important chemical substance, and many matters need to be paid attention to during storage and transportation.
    When storing, the first choice of environment. It should be placed in a cool, dry and well-ventilated place. This is because if it is in a high temperature environment or triggers a chemical reaction, its quality will be damaged. Humid environment is also poor, which can easily cause the substance to be damp and deteriorate, affecting its chemical properties and purity.
    Furthermore, care should be taken to avoid mixing with incompatible substances. 5-Chloropyrazine-2-carboxylic acid may react with some oxidizing agents, reducing agents, etc., so it should be stored separately from such substances to prevent accidental chemical reactions and ensure the safety of storage.
    When transporting, the packaging must be stable and tight. Appropriate packaging materials must be selected to ensure that the substance is not damaged and leaked due to vibration, collision during transportation. If it is a long-distance transportation, it is necessary to strengthen packaging protection to resist the bumps in the road.
    At the same time, the transportation process should strictly follow relevant regulations and standards. Transporters need to be familiar with the characteristics of the substance and understand emergency treatment methods in case of leakage, and can take appropriate measures in time to avoid harm to the environment and personal safety.
    In conclusion, whether it is storing or transporting 5-chloropyrazine-2-carboxylic acid, it is necessary to take care of the environment, mixing, packaging and compliance with regulations to ensure the safety and quality of the substance.