5 Amino 5 Cyanopyrazine
pyridine pyrrole pyrazine piperidine piperazine

5-amino-5-cyanopyrazine

    Specifications

    HS Code

    947243

    Name 5 - amino - 5 - cyanopyrazine
    Molecular Formula C5H4N4
    Molar Mass 120.11 g/mol
    Appearance Solid (usually white or off - white)

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    General Information
    Where to Buy 5-amino-5-cyanopyrazine in China?
    As a trusted 5-amino-5-cyanopyrazine manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 5-amino-5-cyanopyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 5-amino-5-cyanopyrazine?
    5-Amino-5-cyanopyrazine, which is 5-amino-5-cyanopyrazine, has a wide range of uses. In the field of pharmaceutical chemistry, it is a key intermediate for the synthesis of a variety of specific drugs. Due to the special structure of this compound, it endows the prepared drug with unique pharmacological activity, which can be used to develop innovative drugs for specific diseases, and has great potential in anti-disease treatment.
    In the field of materials science, 5-amino-5-cyanopyrazine also plays an important role. Due to its ability to participate in the material synthesis process, ingeniously designed and reacted, new materials with unique properties can be prepared, such as materials with special optical, electrical or mechanical properties, which have potential applications in electronic devices, optical instruments and many other fields.
    In the field of organic synthesis, it is an important synthetic building block that can construct more complex organic molecular structures through various chemical reactions with other organic compounds. With its amino and cyano groups, it can perform a variety of functional group conversion reactions, providing organic synthesis chemists with a wealth of strategies and approaches to help create organic compounds with diverse structures and functions, thus promoting the continuous development and innovation of organic synthesis chemistry.
    What are the physical properties of 5-amino-5-cyanopyrazine?
    5-Amino-5-cyanopyrazine is one of the organic compounds. Its physical properties are particularly important and are related to applications in many fields.
    Looking at its appearance, it often shows a crystalline powder like white to light yellow, which is easy to identify and operate. Its color and texture are of characterization significance in practical application and storage.
    When it comes to melting point, the melting point of this compound is quite high, about 250 ° C. The level of melting point not only reflects the strength of the intermolecular force, but also highlights its thermal stability. High melting point means that its structure can remain stable under relatively high temperature environment, and it is not easy to melt and deform. It can be an important consideration when processing at high temperature.
    In terms of solubility, the solubility of 5-amino-5-cyanopyrazine in water is very small, which is closely related to the polarity of water molecules and the structure of the compound itself. However, in some organic solvents, such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), etc., it shows good solubility. This difference in solubility has a significant impact on chemical synthesis, separation and purification, and pharmaceutical preparations. In chemical synthesis, suitable solvents can promote the reaction and improve the yield; in separation and purification, the appropriate solvent system is selected according to its solubility, which helps to effectively separate it from the mixture; in the field of pharmaceutical preparations, solubility is related to the absorption and bioavailability of drugs.
    Furthermore, its density is about 1.48 g/cm ³, and the value of density affects its distribution and transmission in different media. In materials science and chemical engineering, density parameters are often used to calculate the amount of materials, the volume of the reaction system, etc., which is crucial for process design and optimization.
    In summary, the physical properties of 5-amino-5-cyanopyrazine, such as appearance, melting point, solubility, and density, each have their own importance and are indispensable factors for research and application in many fields.
    What is 5-amino-5-cyanopyrazine chemical synthesis method?
    The method of synthesis of 5-amino-5-cyanopyrazine is one of the most important tasks in chemical research. To make this substance, one of the common methods is to use pyrazine derivatives as the starting material. First take a suitable pyrazine precursor, in a suitable reaction environment, with specific reagents and conditions, so that it can be gradually converted.
    The first step, or choose a pyrazine compound, its structure should have a modifiable check point, that is, the amino group and cyano group are introduced into the base. Placing this pyrazine substrate in the reactor, adding an appropriate amount of base, base, can adjust the pH of the reaction system, so that the reaction is smooth. In this environment, reagents that can provide amino groups, such as ammonia derivatives, are added. Through nucleophilic substitution and other reaction mechanisms, the amino groups are gradually connected to specific positions on the pyrazine ring. This process requires fine temperature control. If the temperature is too high or too low, the reaction rate can be abnormal or by-products can be formed.
    After the amino group is connected, the next step is the introduction of the cyano group. At this time, it can provide sources of cyanide, such as potassium cyanide, sodium cyanide, etc. (when using this type of cyanide, pay attention to its toxicity and strictly abide by the operating specifications). Under another specific reaction condition, or accompanied by a catalyst, the cyano group is promoted to react with the amino-containing pyrazine intermediate to obtain 5-amino-5-cyanopyrazine.
    There are other methods, or starting from more basic raw materials, through multi-step reactions, the pyrazine ring is constructed, and the amino group and cyano are introduced in an orderly manner. For example, small molecules containing nitrogen and carbon are gradually constructed by a series of reactions such as condensation and cyclization. However, this path is often complicated and requires precise control of each step of the reaction. The purity and yield of the product can be affected from the proportion of raw materials, reaction time, and even the material and stirring rate of the reaction equipment.
    The method of preparing 5-amino-5-cyanopyrazine, although not the same, requires following chemical principles and operating procedures to be expected to obtain pure and sufficient products.
    What is the price of 5-amino-5-cyanopyrazine in the market?
    5-Amino-5-cyanopyrazine is in the market, and its price is difficult to determine. The market situation of this compound often changes due to a variety of reasons. Its preparation is difficult and easy, and it depends on the price. If the preparation method is difficult, requires multiple processes, special reagents, and the yield is not high, its price is high or high. On the contrary, if the preparation is easier, the price or slightly cheaper.
    Furthermore, the state of market supply and demand also affects its price. If there are many applicants, but there are few suppliers, the price will tend to rise; if the supply exceeds the demand, the price may fall. In addition, the price of raw materials is also a major factor. If the price of raw materials is high, the cost of 5-amino-5-cyanopyrazine will increase, and its market price will also rise accordingly.
    And different suppliers and different quality specifications have different prices. The better price is high, and the second price is low. To know the exact price, you need to consult the supplier of chemical raw materials and compare the quotations of different merchants to get a more realistic price. In addition, the chemical market is changing, and prices rise and fall from time to time, so it is difficult to get a temporary price, and it is difficult to prevail for a long time.
    What are 5-amino-5-cyanopyrazine manufacturers?
    5-Amino-5-cyanopyrazine is an organic compound, which is very important in the fields of chemical industry and pharmaceutical research and development. However, no clear records have been found in ancient books, because it is a product of modern chemical synthesis. In today's world, many chemical companies and scientific research institutions are committed to the production of such compounds.
    Overseas, such as Sigma-Aldrich in the United States, it is a giant in the supply of chemical reagents, providing a variety of purity and specifications of 5-amino-5-cyanopyrazine to meet the needs of scientific research and industrial production. In addition, Merck in Germany has also made outstanding achievements in the field of fine chemicals, or is involved in the production and sales of this compound.
    In China, many chemical companies are also involved in the production of this compound. For example, some chemical companies in Jiangsu, with their advanced synthesis technology and large-scale capacity, not only meet domestic demand, but also enter the international market. In addition, some scientific research enterprises in Shanghai, with their strong R & D strength, can provide high-purity, customized 5-amino-5-cyanopyrazine products to meet the requirements of high-end scientific research and special industrial applications.
    Although there are no manufacturers of this compound in ancient books, the chemical industry is booming today, and many domestic and foreign companies have become important producers, providing a solid material foundation for the development of related fields.