3 Hydroxypyrazine 2 Carboxamide
pyridine pyrrole pyrazine piperidine piperazine

3-Hydroxypyrazine-2-carboxamide

    Specifications

    HS Code

    435568

    Chemical Formula C5H5N3O2
    Molar Mass 139.11 g/mol
    Appearance Solid (usually white to off - white powder)
    Solubility In Water Moderately soluble
    Melting Point 180 - 184 °C (reported range)
    Boiling Point Decomposes before boiling
    Density N/A (no common data, usually considered as a powder, density of solid form may vary with packing)
    Pka N/A (no common data for this specific compound's pKa values)
    Odor Odorless (usually)
    Stability Stable under normal conditions, but may decompose on heating or under strong acidic/basic conditions

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    General Information
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    Frequently Asked Questions

    As a leading 3-Hydroxypyrazine-2-carboxamide supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-Hydroxypyrazine-2-carboxamide?
    3-Hydroxypyrazine-2-formamide is an important organic compound. It has a wide range of uses and has extraordinary applications in many fields.
    First in the field of medicine. This substance may have unique pharmacological activity and can be used as a potential drug lead compound. After in-depth research and modification, it is expected to develop new drugs for the fight against various diseases. Due to modern medical research, it is often focused on exploring molecules with specific biological activities to precisely act on disease targets. The structural characteristics of 3-hydroxypyrazine-2-formamide may give it the ability to interact with key molecules in the body, such as binding with specific enzymes and receptors, thereby regulating physiological functions and treating diseases.
    Furthermore, in the field of materials science, it may also have significant uses. It may participate in the synthesis of new functional materials. Because its chemical structure contains specific functional groups, it can chemically react with other substances to construct materials with special properties. For example, in optical materials, it can give materials unique optical properties; in electrical materials, it may also affect the electrical properties of materials, helping to develop new materials with excellent performance to meet the urgent needs of today's scientific and technological development for high-performance materials.
    In addition, in the field of organic synthetic chemistry, 3-hydroxypyrazine-2-formamide can be used as an important synthetic intermediate. With its structural characteristics, it can be converted into more complex and diverse organic compounds through a series of chemical reactions. Organic synthesis aims to build various organic molecules. The existence of this compound provides synthetic chemists with more synthetic paths and possibilities, promoting the continuous development and innovation of organic synthetic chemistry, enriching the types and structures of organic compounds, and laying the foundation for applications in other fields.
    What are the chemical properties of 3-Hydroxypyrazine-2-carboxamide?
    3-Hydroxypyrazine-2-formamide, this material is unique and has the properties of acid and base. Its hydroxyl group can release protons and is weakly acidic; the nitrogen of the amide group can accept protons and is weakly basic. Because of its nitrogen-containing heterocyclic and amide structure, it has a certain polarity and has a certain solubility in water and polar organic solvents, such as methanol, ethanol, and dimethyl sulfoxide.
    Its structure is stable, and it can react when exposed to strong acids, strong bases, or high temperatures. In acidic media, amide groups or hydrolysis into carboxylic acids and amines; in alkaline conditions, hydroxyl groups or salts. And because the compound contains a conjugated system, it has ultraviolet absorption characteristics and has absorption peaks at specific wavelengths, which can be detected by ultraviolet spectroscopy.
    In addition, its nitrogen heterocycle and amide structure make it have certain biological activity. It is used in the field of medicine and pesticide research and development, or as an important intermediate, participating in many organic synthesis reactions to construct complex compound structures, showing diverse chemical properties and potential application value.
    What is 3-Hydroxypyrazine-2-carboxamide synthesis method?
    The synthesis of 3-hydroxypyrazine-2-formamide is quite complicated and requires a delicate method. In the past, many specific steps were followed to prepare this substance.
    First, pyrazine is often used as the initial raw material. Pyrazine has a stable cyclic structure, but its activity can lead to reactions. In a suitable reaction environment, such as in a specific solvent, appropriate reagents are added to replace the specific position of the pyrazine ring. Halogenation can be used to introduce halogen atoms on the pyrazine ring, which are the key to subsequent reactions.
    Secondly, after halogenation, the nucleophilic substitution reaction is used to replace the halogen atom with a reagent containing hydroxyl groups, so as to introduce hydroxyl groups into the pyrazine ring. This step requires precise control of the reaction conditions, such as temperature, pH, etc. If the temperature is too high or too low, the reaction can be biased to other ways, or the reaction can be delayed. The imbalance of pH may also cause the reactants to decompose, or the reaction cannot proceed.
    Furthermore, at another specific position of the pyrazine ring, an amidation reaction is carried out with a suitable amidation reagent to introduce carboxyamide groups. This process requires attention to the activity and selectivity of the reagent to ensure that the carboxyamide groups are accurately connected to the target location.
    The synthesis process requires fine operation at every step. After the reaction is completed, it needs to be separated and purified to obtain pure 3-hydroxypyrazine-2-formamide. During separation, column chromatography, recrystallization and other methods can be used to remove its impurities and make the product reach the required purity.
    What is the market outlook for 3-Hydroxypyrazine-2-carboxamide?
    3-Hydroxypyrazine-2-formamide is a promising compound that has shown unique value in various fields such as medicine and chemical industry, and the market prospect is quite promising.
    Looking at the field of medicine, with the in-depth study of the pathogenesis of diseases, the demand for new therapeutic drugs is increasing day by day. 3-Hydroxypyrazine-2-formamide may be used as a lead compound to develop drugs for specific diseases due to its specific chemical structure and biological activity. For example, in the development of anti-tumor drugs, it may interfere with the growth and proliferation of tumor cells through specific mechanisms of action, bringing new hope for the fight against cancer. At present, the number of cancer patients in the world remains high, and the market size of anti-tumor drugs continues to expand, which undoubtedly opens up a broad market space for the application of 3-hydroxypyrazine-2-formamide in pharmaceutical research and development.
    The chemical industry is also where 3-hydroxypyrazine-2-formamide shines. It can be used as a key intermediate for the synthesis of a variety of fine chemicals. With the chemical industry's pursuit of refined and high-end products, the demand for high-quality intermediates continues to rise. The unique chemical properties of 3-hydroxypyrazine-2-formamide can help to synthesize many chemical products with excellent performance, such as high-performance materials and special function additives. With the rapid development of materials science, the market demand for these high-end chemical products is strong, making 3-hydroxypyrazine-2-formamide occupy an important position in the chemical industry chain.
    However, the development of the 3-hydroxypyrazine-2-formamide market also faces challenges. First, the optimization of the synthesis process and cost control are key problems. In order to achieve large-scale industrial production, it is necessary to develop more efficient and economical synthetic routes and reduce production costs in order to enhance the market competitiveness of products. Second, regulations and supervision are becoming increasingly strict. In the fields of medicine and chemical industry, product safety and quality requirements are extremely high. 3-Hydroxypyrazine-2-formamide related products must meet strict regulatory standards, which puts forward higher requirements for the R & D and production management capabilities of production enterprises. But overall, with the advancement of science and technology and the promotion of market demand, 3-Hydroxypyrazine-2-formamide is expected to shine in various fields and have a bright market prospect.
    What are the relevant safety precautions for 3-Hydroxypyrazine-2-carboxamide?
    3-Hydroxypyrazine-2-formamide is a special chemical. Many safety precautions must be kept in mind when using and contacting it.
    One is related to toxicity. The toxicity information of this substance may be limited, but when handling it, it should still be regarded as potentially toxic. Do not come into contact with the skin. If you come into contact with it inadvertently, rinse it with plenty of water immediately, and rinse it for a long time to remove the contaminated substance. If the contact area is large or uncomfortable, seek medical attention immediately. Do not let it come into contact with the eyes. Once in the eyes, be sure to rinse with flowing water or normal saline immediately, and seek medical assistance. Inhalation by mouth and nose should also be avoided. The operation should be carried out in a well-ventilated place, preferably in a fume hood to prevent inhalation of dust or steam. If inhaled, it should be rushed to a place with fresh air. If breathing difficulties, oxygen needs to be inhaled and medical treatment is required.
    Second, storage. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources. Due to its chemical properties, it needs to be stored separately from oxidants, acids, alkalis, etc., and must not be mixed to prevent dangerous chemical reactions. The packaging must also be sealed to avoid moisture and deterioration.
    Third, when using and operating. Wear appropriate protective equipment, such as protective gloves, goggles, gas masks, etc., to ensure your own safety. The operation process should be rigorous to prevent dust from flying and spreading. After the experiment is completed, the equipment used should be properly cleaned to avoid subsequent dangers caused by residual substances.
    Fourth, waste disposal. It cannot be discarded at will, and must be disposed of in accordance with relevant regulations and standards. Generally speaking, it should be handed over to a professional waste treatment agency and handled in an appropriate manner according to its characteristics to prevent pollution hazards to the environment.
    In general, when treating 3-hydroxypyrazine-2-formamide, regardless of storage, use or waste disposal, care must be taken and safety regulations must be strictly followed, so as to ensure the safety of personnel and the environment.