3-bromoimidazo[1,2-a]pyrazine

3-Bromoimidazo [1,2-a] pyrazine, one of the organic compounds. The chemical structure of this compound is imidazolo [1,2-a] pyrazine as the parent nucleus, and a bromine atom is connected to its 3-position carbon.
The structure of fulimidazolo [1,2-a] pyrazine is formed by fusing imidazole ring with pyrazine ring. The imidazole ring has a five-membered ring structure, containing two nitrogen atoms, and the position of the nitrogen atom makes the ring have a certain electron cloud distribution and chemical activity. The pyrazine ring is a six-membered ring, which also contains two nitrogen atoms, and presents a planar structure. After fusing the two rings, a unique conjugated system is formed, which endows the parent nucleus with special physical and chemical properties.
As for the bromine atom connected to the 3-position, it is a halogen element and has strong electronegativity. The presence of bromine atoms significantly affects the electron cloud density distribution of the molecule, changes its polarity, and then affects the solubility and reactivity of the compound. Due to its electronegativity, bromine atoms can reduce the electron cloud density around the 3-position carbon, making this position vulnerable to attack by nucleophiles, triggering various chemical changes such as substitution reactions, which is of great significance in the field of organic synthesis.

3-Bromoimidazo [1,2-a] pyrazine, Chinese name or 3-bromoimidazo [1,2-a] pyrazine, is widely used in the fields of medicine, materials science, and chemistry.
In the field of medicine, it is often used as an intermediate in organic synthesis to create new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms or develop therapies for specific diseases. For example, in the development of anti-cancer drugs, scientists modify their chemical structures in the hope of enhancing the targeting of drugs to cancer cells, improving anti-cancer efficacy, and reducing damage to normal cells.
In the field of materials science, 3-bromoimidazo [1,2-a] pyrazine can participate in the preparation of special functional materials. Due to its structural properties, it may endow the material with unique electrical and optical properties. For example, in the preparation of organic Light Emitting Diode (OLED) materials, adding this substance may optimize the luminous efficiency and stability of the material, thereby improving the display effect and service life of OLED displays.
In the field of chemical research, it is an important organic reagent. Chemists use it to participate in various chemical reactions to explore new synthesis pathways and reaction mechanisms. By studying its reaction characteristics, organic synthesis methodologies can be expanded, new ideas and methods can be provided for the synthesis of more complex organic compounds, and the continuous development of chemistry can be promoted.

3-Bromoimidazo [1,2-a] pyrazine is an important organic compound. Its synthesis methods are diverse, and each has its own advantages and disadvantages. The following is described in detail by you.
First, imidazolo [1,2-a] pyrazine is used as the starting material to introduce bromine atoms by halogenation reaction. Brominating reagents such as bromine (Br ²), N-bromosuccinimide (NBS), etc. can be selected. If bromine is used, it usually needs to be carried out in suitable solvents such as dichloromethane and carbon tetrachloride, and catalysts such as iron powder and iron tribromide are often required to promote the reaction. The advantage of this method is that the raw materials are easily available and the reaction conditions are relatively mild; the disadvantage is that the selectivity is sometimes poor, or side reactions occur, resulting in the formation of polybrominated products.
Second, bromine atoms can be introduced by constructing imidazolo [1,2-a] pyrazine rings. For example, bromine-containing pyridine or pyrazine derivatives are synthesized by cyclization with suitable nitrogen-containing reagents. The advantage of this strategy is that the steps may be simplified and the complex side reactions that may be generated by subsequent halogenation can be avoided. The disadvantage is that the synthesis of starting materials is more complex, and the reaction conditions are strict, and the reaction parameters need to be precisely controlled to ensure the smooth progress of the cyclization reaction.
Third, the coupling reaction catalyzed by transition metals is used. For example, halogenated imidazolo [1,2-a] pyrazine is coupled with brominated organometallic reagents under the action of transition metal catalysts such as palladium catalysts. This method has the advantage of high selectivity and can accurately construct the target product; however, the disadvantage is that the catalyst cost is high, and the reaction system requires strict anhydrous and anaerobic conditions, which makes the operation cumbersome.
When synthesizing 3-bromoimidazo [1,2-a] pyrazine, the most suitable synthesis method should be selected according to the actual situation, such as the availability of raw materials, cost, and purity requirements of the target product.

3-Bromoimidazo [1,2-a] pyrazine (3-bromimidazo [1,2-a] pyrazine) is a kind of organic compound. Looking at its physical properties, it may be solid under normal conditions, but the exact physical form is also determined by its purity and surrounding environmental factors.
When it comes to melting point, it is difficult to give accurately for the time being due to limited data. However, it is known that the melting point of this compound with different purity varies slightly. Generally speaking, the melting point of organic compounds can be accurately measured by melting point meters, and this value is crucial for the identification and purification of compounds.
In terms of boiling point, the exact value is also lacking. The boiling point of 3-bromoimidazo [1,2-a] pyrazine is controlled by intermolecular forces. There are van der Waals forces and hydrogen bonds between the molecules, resulting in its boiling point or a specific range. It can be determined by experimental means such as distillation, which is of great significance for the separation and purification of compounds.
In terms of solubility, the compound has good solubility in organic solvents, such as common ethanol, dichloromethane, ether, etc. Due to the principle of "similar miscibility", its organic structure is compatible with the molecular structure of organic solvents. Solubility in water or poor, because its molecular polarity does not match that of water.
Appearance may be white to light yellow crystalline powder, but it is only commonly speculated from similar compounds. Purity, synthetic method, and impurity conditions can all cause changes in appearance, color, and morphology. The physical properties of
3-bromoimidazo [1,2-a] pyrazine are crucial in the fields of organic synthesis and medicinal chemistry. In organic synthesis, properties such as melting point, boiling point, and solubility assist chemists in planning reaction conditions and isolating products. In medicinal chemistry, these properties are related to drug absorption, distribution, and metabolism, and affect the drug development process.

I don't know what the price range of 3-bromoimidazo [1,2-a] pyrazine is on the market. This compound is unusually easy to obtain, and its price is determined by many factors.
First, the difficulty of preparation has a great impact. If the synthesis requires complicated steps, rare raw materials or harsh reaction conditions, the cost will be high, and the price will also rise. Second, the amount of market demand is related to the price. If the demand is strong and the supply is limited, the price is naturally high; if the demand is low, the merchant may reduce the price to promote the sale. Third, purity is also the key. For high purity, the preparation cost is high, and the price is not cheap; for less pure, the price may be slightly lower.
However, we have not found the exact price information, and it is difficult to determine its price range. For details, you may consult chemical product suppliers, chemical reagent sales platforms, and they may be able to tell the exact price range.