2 Pyrazinecarboxamide N 2 4 Aminosulfonyl Phenyl Ethyl 5 Methyl
pyridine pyrrole pyrazine piperidine piperazine

2-Pyrazinecarboxamide, N-[2-[4-(aminosulfonyl)phenyl]ethyl]-5-methyl-

    Specifications

    HS Code

    705162

    Chemical Formula C14H18N4O3S
    Iupac Name N-(2-(4-(aminosulfonyl)phenyl)ethyl)-5-methylpyrazine-2-carboxamide
    Appearance Solid (predicted, as specific appearance data may vary)
    Physical State Solid at standard conditions
    Solubility Solubility characteristics would depend on solvents, predicted to have low solubility in water, higher in organic solvents like DMSO
    Pka No common data available without experimental work, acidic/basic nature influenced by amide, sulfonamide groups
    Logp Predicted to have a certain lipophilicity due to aromatic and alkyl groups, value would need experimental or computational determination

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    2-Pyrazinecarboxamide, what is the chemical structure of N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl-
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    First look at "2 - Pyrazinecarboxamide", which is a nitrogen-containing heterocyclic compound, the pyrazine ring is connected to the formamide group, which is the basic part of the structure.
    Look again at "N - [2 - [4 - (aminosulfonyl) phenyl] ethyl]", this paragraph indicates that the nitrogen atom is connected to an ethyl group, and the ethyl group is connected to a benzene ring, and the p-position of the benzene ring has aminosulfonyl, which is an important side chain of the structure.
    Finally "5 - methyl -", indicating that there is a methyl substitution at the 5th position of the pyrazine ring.
    In combination, the overall chemical structure is based on a pyrazine ring, with a formamide group attached to the ring, and a methyl group at the 5th position of the ring; at the same time, the nitrogen atom is connected to a specific side chain, which is composed of ethyl, benzene ring and para-aminosulfonyl group. In this way, the chemical structure of this compound is clear.
    2-Pyrazinecarboxamide, what are the physical properties of N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl-
    2-Pyrazine formamide, $N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl - This substance is an organic compound with unique physical properties. Its properties may be crystalline powder, and its solubility varies in different solvents due to the variety of groups in the molecular structure. In polar solvents such as water, aminosulfonyl groups can form hydrogen bonds with water molecules, or have a certain solubility, but in view of the presence of non-polar pyrazine rings and methyl groups in the molecule, the overall water solubility may not be very high. In organic solvents, such as ethanol and acetone, according to the principle of similarity dissolution, the molecule may have better dissolution performance due to the combination of polar and non-polar regions.
    Its melting point and boiling point are also determined by intermolecular forces. Interactions such as hydrogen bonds and van der Waals forces in the molecule require a specific energy to change its physical state. It is expected that the melting point is within a certain range. At this temperature, the molecule overcomes the lattice energy, the lattice structure disintegrates, and converts from a solid to a liquid state. The boiling point is higher, when the molecule obtains enough energy to break free from the liquid phase and become a gaseous state.
    In addition, the density of the compound is also an important physical property, which is closely related to its molecular mass and the degree of molecular accumulation. Due to the structure containing multiple atoms, the molecular mass is relatively large. If the molecules are packed tightly in the crystal, the density may be high. These physical properties are of great significance for their applications in chemical synthesis, drug development and other fields, and can help researchers choose suitable separation, purification and reaction conditions.
    2-Pyrazinecarboxamide, what is the use of N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl-
    2-Pyrazine formamide, N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl This substance is used in this world and is really related to the field of medicinal chemistry.
    Looking at the past, although there is no ancient book directly recording this substance, according to the current medical theory, its structure is unique or has specific pharmacological activities. In the process of drug development, compounds with novel structures are often explored in order to discover new therapeutic effects.
    Some structural fragments of this compound may bind to receptors to intervene in physiological and biochemical processes. For example, pyrazine formamide fragments are common in anti-tuberculosis drugs and may be involved in regulating cellular metabolic pathways. The N - [2 - [4 - (aminosulfonyl) phenyl] ethyl] -5 -methyl moiety, or endow it with targeting, can precisely act on specific cell or molecular targets.
    Or used to develop new anti-tumor drugs, through its structure to interact with cancer cell-related targets, inhibit cancer cell proliferation and induce apoptosis; or in the development of autoimmune disease drugs, regulate immune cell function and correct immune imbalance. Although there is no ancient precedent, today's medical researchers are following the scientific method to explore its potential uses, with the aim of seeking well-being for human health.
    2-Pyrazinecarboxamide, what is the synthesis method of N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl-
    To prepare 2-pyrazine formamide, N - [2 - [4 - (aminosulfonyl) phenyl] ethyl] -5 -methyl, the synthesis method is as follows.
    First take pyrazine as the starting material, and introduce carboxyl groups at its 2 positions, which can be achieved by suitable oxidation reactions. For example, under the conditions of moderate temperature and pressure and the assistance of catalysts, the group at a specific position of pyrazine is converted into carboxyl groups to obtain 2-pyrazinecarboxylic acid.
    Then, the 2-pyrazinecarboxylic acid interacts with reagents such as thionyl chloride to convert carboxyl groups into acid chloride. This acid chloride has good activity. Then take an amine compound containing [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl and react with it. The amine nucleophilic attacks the carbonyl carbon of the acyl chloride, removes hydrogen chloride, and forms the required amide bond, so as to obtain the main structure of the target product.
    During the reaction process, attention should be paid to the control of the reaction conditions. The temperature should not be too high or too low. If it is too high, the side reaction will be easy to produce, and if it is too low, the reaction rate will be slow. The purity of the reagent used is also crucial. Impure reagents or impurities are mixed in to affect the purity of the product. And the reaction system needs to maintain an appropriate pH, which can be adjusted with a buffer to facilitate the reaction to proceed in the desired direction. At the same time, the reaction time also needs to be accurately grasped. If it is too short, the reaction will not be completed, and if it is too long, it may cause product decomposition or other side reactions. In this way, after many fine operations and adjustments, 2-pyrazine formamide, N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl can be obtained.
    2-Pyrazinecarboxamide, N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl-related safety precautions
    2-Pyrazine formamide, N- [2- [4- (aminosulfonyl) phenyl] ethyl] -5-methyl, the relevant safety precautions for this chemical are as follows:
    First, the toxicity of chemical substances should be cautious. Although the exact toxicity is not known, many of these organically synthesized compounds may have certain toxicity. Or they can invade the human body by inhalation, skin contact or ingestion, harming human health. If inhaled, or cause respiratory irritation, causing cough, asthma, dyspnea and other diseases; skin contact, or cause allergies, redness, swelling, itching and even burns; accidental ingestion or damage to the digestive system, causing nausea, vomiting, abdominal pain, diarrhea, etc., or even involving other organs.
    Second, fire safety should not be ignored. When storing and using, its flammability should be carefully observed. If it is flammable substances, in case of open fire, hot topic or risk of explosion. Store away from fire and heat sources, and prepare suitable fire extinguishing equipment, such as dry powder fire extinguishers, carbon dioxide fire extinguishers, etc., just in case.
    Third, storage conditions must be appropriate. It should be stored in a cool, dry and well-ventilated place, away from direct sunlight, to prevent package damage from causing it to react and deteriorate with air, moisture, etc., affecting its stability and safety, and do not mix with oxidants, acids, alkalis, etc., to prevent dangerous reactions.
    Fourth, the operation protection must be comprehensive. When operating, wear protective gloves and goggles in front of appropriate protective clothing to prevent contact injuries. If operating in a poorly ventilated place, it is necessary to prepare effective ventilation equipment or wear a gas mask to ensure the safety of the air inhaled. In case of accidental contact during operation, the corresponding parts should be rinsed with a large amount of water according to different contact routes, and seek medical treatment as soon as possible if necessary.