2 Ethoxy 3 Isopropylpyrazine
pyridine pyrrole pyrazine piperidine piperazine

2-ethoxy-3-isopropylpyrazine

    Specifications

    HS Code

    947644

    Chemical Formula C9H16N2O
    Molecular Weight 168.24
    Appearance Colorless to pale yellow liquid
    Odor Nutty, earthy, roasted odor
    Boiling Point Around 214 - 216 °C
    Density Approx. 0.98 g/cm³
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, acetone
    Flash Point Around 88 °C

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    General Information
    Where to Buy 2-ethoxy-3-isopropylpyrazine in China?
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    Frequently Asked Questions

    As a leading 2-ethoxy-3-isopropylpyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-ethoxy-3-isopropylpyrazine?
    2-Ethoxy-3-isopropylpyrazine, this is an organic compound. It has a wide range of uses and is often used as a edible fragrance in the field of flavors, which can add a unique flavor to food. Because of its special aroma, it can be used in baked goods, candies, beverages, etc., to enhance the aroma level and taste of products and give a different flavor experience.
    In the field of chemical synthesis, it is also a key intermediate. Through a series of chemical reactions, it can be converted into other compounds with special properties and uses for the preparation of drugs, pesticides and other fine chemicals. Due to its structural properties, it can introduce specific groups for new compounds, which affect the properties and activities of the products.
    In terms of scientific research and exploration, it provides important materials for chemical research. Researchers can deepen their theoretical understanding of organic chemistry by studying its reaction characteristics, physical and chemical properties, etc., expand the methods and strategies of organic synthesis, and promote the progress and development of organic chemistry.
    Therefore, 2-ethoxy-3-isopropylpyrazine has important value in many fields such as food, chemical industry and scientific research, providing strong support for the development of related industries and scientific research.
    What are the physical properties of 2-ethoxy-3-isopropylpyrazine?
    2-Ethoxy-3-isopropylpyrazine is also an organic compound. Its physical properties are particularly important and are described as follows:
    First appearance, under room temperature and pressure, 2-ethoxy-3-isopropylpyrazine is a colorless to light yellow transparent liquid. The appearance is clear, with no visible impurities. Under the light, it is slightly shiny, just like the radiance of morning dew.
    Second and smell, this material has a unique aromatic smell, the aroma is complex and attractive, with a slight mixture of nuts and roasted aroma. It smells like being in a baking workshop, which is pleasant.
    When it comes to the boiling point, it is between 190 and 200 ° C. At this temperature, the substance gradually changes from the liquid state to the gaseous state, and the molecular motion intensifies, breaking free from the liquid phase. This boiling point value is measured at standard atmospheric pressure. If the air pressure changes, the boiling point also changes.
    Besides the melting point, its melting point is lower, about - 20 ° C. At this temperature, the substance solidifies from the liquid state to the solid state, and the molecular arrangement tends to be ordered from disorder, forming a regular lattice structure.
    In terms of solubility, 2-ethoxy-3-isopropylpyrazine is slightly soluble in water, but more soluble in common organic solvents such as ethanol, ether, acetone, etc. In organic solvents, its molecules interact with solvent molecules to disperse uniformly, just like fish swimming in water, free to blend.
    The density is about 1.02 - 1.06 g/cm ³, which is slightly heavier than water. When it drops on the water surface, it slowly sinks, just like a stone flat lake, sinking to the bottom.
    Its refractive index also has a specific value, between about 1.500 - 1.520. This property is related to the degree of refraction of light when it passes through the material, causing the light to change its propagation path in it, presenting a unique optical phenomenon.
    What is the chemistry of 2-ethoxy-3-isopropylpyrazine?
    2-Ethoxy-3-isopropylpyrazine is one of the organic compounds. It has specific chemical properties and is of great significance in the field of organic synthesis.
    This compound is often colorless to light yellow liquid in appearance and is relatively stable at room temperature and pressure. Looking at its physical properties, its boiling point, melting point, etc. are all related to the interaction between atoms in the molecular structure. Due to the presence of ethoxy and isopropyl in the molecule, its boiling point will be affected. Specifically, the presence of ethoxy and isopropyl increases the intermolecular force, making the boiling point relatively high.
    When it comes to chemical properties, the nitrogen atom on the pyrazine ring in 2-ethoxy-3-isopropyl pyrazine has a certain alkalinity and can react with acids to form corresponding salts. For example, when encountering strong acids, nitrogen atoms will accept protons and produce protonated products. At the same time, its ethoxy part can undergo nucleophilic substitution reactions due to the electronegativity of oxygen atoms. In case of nucleophilic reagents, ethoxy can be replaced to form new compounds. In addition, the carbon-carbon bond and carbon-hydrogen bond in isopropyl can undergo oxidation and halogenation reactions under appropriate conditions.
    In the field of organic synthesis, 2-ethoxy-3-isopropylpyrazine can be used as a key intermediate. Due to its special structure, more complex organic molecules can be constructed through various chemical reactions. For example, using it as a starting material, by modifying the substituents on the pyrazine ring, a series of compounds with different biological activities or physical properties can be prepared, which have potential applications in drug development, materials science and many other fields.
    What is 2-ethoxy-3-isopropylpyrazine production method?
    There are many ways to synthesize 2-ethoxy-3-isopropylpyrazine. The common one is to use pyrazine as the starting material and to prepare it by substitution reaction.
    First, pyrazine and halogenated ethane are heated and stirred in an organic solvent such as acetonitrile in the presence of a suitable base, such as potassium carbonate. This step is a nucleophilic substitution reaction, in which the halogen atom of the halogenated ethane leaves, and the ethoxy group is attached to the pyrazine ring to obtain the ethoxy-containing pyrazine derivative.
    Then, the resulting product is obtained, and then the nucleophilic substitution is repeated with an isopropylation reagent, such as isopropyl halide, in similar basic conditions and organic solvents. After careful temperature control and stirring, the isopropyl group is successfully connected to the specific position of the pyrazine ring, and then 2-ethoxy-3-isopropyl pyrazine is obtained.
    There are also other methods, using pyrazine derivatives containing specific substituents as raw materials, through functional group conversion. For example, a pyrazine compound with suitable substituents is first prepared. The substituents are gradually converted into ethoxy and isopropyl groups under specific reaction conditions, or oxidation, reduction, or rearrangement, etc., and the final product is obtained. This process requires fine regulation of reaction conditions to ensure that the reaction proceeds according to the expected path and the purity and yield of the product are good. All methods have their own advantages and disadvantages. In actual preparation, the choice should be based on factors such as the availability of raw materials, cost, and difficulty of reaction.
    2-ethoxy-3-isopropylpyrazine is widely used in which areas
    2-Ethoxy-3-isopropylpyrazine is widely used in the fields of fragrances, medicine and pesticides.
    In the field of fragrances, it emits a unique aroma and can be added to various flavors. Because it can give flavors a different flavor, it is used in food, beverage, cosmetics and other industries. For example, in the food industry, it can enhance the flavor and taste of baked goods, candies, etc., create a unique olfactory experience, improve product quality and attractiveness, and make consumers more likely to favor.
    In the field of medicine, such compounds may have certain biological activities. or can become a key intermediate in drug development, through a series of chemical reactions, converted into drugs with specific pharmacological effects. For example, some pyrazine derivatives have potential effects on the treatment or prevention of specific diseases, and 2-ethoxy-3-isopropylpyrazine may be listed here, providing possibilities for pharmaceutical innovation.
    In the field of pesticides, due to its structural characteristics, it may be able to derive high-efficiency and low-toxicity pesticide products. It can play a role in targeting specific pests or pathogens, ensuring the growth of crops, improving yield and quality. And compared with traditional pesticides, such pesticides developed based on this compound may be more suitable for environmental protection needs, with less harm to the environment and conducive to sustainable agricultural development.
    In summary, 2-ethoxy-3-isopropylpyrazine is widely used in the above fields and contributes significantly to the development of various industries.