2 Ethoxy 3 5 6 Methyl Pyrazine
pyridine pyrrole pyrazine piperidine piperazine

2-Ethoxy-3(5/6)-methyl pyrazine

    Specifications

    HS Code

    927737

    Chemical Formula C8H12N2O
    Molecular Weight 152.194 g/mol
    Boiling Point 199 - 201 °C
    Flash Point 79.4 °C
    Density 1.036 g/mL at 25 °C
    Water Solubility Insoluble
    Odor Nutty, roasted odor
    Appearance Colorless to pale yellow liquid

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    General Information
    Where to Buy 2-Ethoxy-3(5/6)-methyl pyrazine in China?
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    Frequently Asked Questions

    As a leading 2-Ethoxy-3(5/6)-methyl pyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Ethoxy-3 (5/6) -methyl pyrazine?
    2-Ethoxy-3 (5/6) -methylpyrazine is one of the organic compounds. It has a wide range of uses and has unique applications in the field of fragrances. This compound can impart unique aroma characteristics to fragrances and is often used to prepare various flavors, such as food flavors, cosmetic flavors, etc. In food flavors, it can increase its flavor, make food emit a unique and attractive fragrance, and enrich the taste experience. In cosmetic flavors, it can help products create a special fragrance atmosphere and enhance consumers' sensory enjoyment.
    Furthermore, it also has its own impact in the field of pharmaceutical chemicals. Or as a key intermediate in the synthesis of certain drugs, it can be converted into pharmaceutical ingredients with specific pharmacological activities through specific chemical reactions. This plays an indispensable role in the development of new drugs. Its structural properties and reactivity provide the possibility for the synthesis of drug molecules with specific structures, enabling scientists to create drugs with better efficacy and fewer side effects.
    In materials science, there may also be potential applications. Due to its special chemical structure, it may participate in the synthesis process of certain materials, which affects the properties of materials, such as stability and conductivity, and then opens up new paths for the development of new materials. Overall, 2-ethoxy-3 (5/6) -methylpyrazine has shown important value in many fields, promoting the development and progress of related industries.
    What are the physical properties of 2-Ethoxy-3 (5/6) -methyl pyrazine?
    2-Ethoxy-3 (5/6) -methylpyrazine, this compound is an organic compound. Its physical properties are quite important and are related to many applications.
    Looking at its properties, at room temperature, it is mostly a colorless to pale yellow liquid with a clear texture. Its color is light and clear, like the thin mist of early morning dew, giving people a sense of purity.
    When it comes to aroma, this compound exudes a unique fragrance, just like the aroma of roasted nuts and rich coffee, with a long and complex charm. This fragrance can attract appetite and lay the foundation for its application in the field of food flavoring.
    Besides, the boiling point is between 190 and 200 degrees Celsius. Just as the boiling point of water is the key node of its qualitative change, this boiling point determines its state change under a specific temperature environment. In this temperature range, molecular activity intensifies, sublimating from liquid to gaseous state.
    As for the density, it is about 1.02 - 1.06 g/cm ³. This value indicates that the mass of a unit volume is determined by the density of an object in water, and its density affects the distribution and state when mixed with other substances.
    In terms of solubility, it has good solubility in organic solvents such as ethanol and ether, just like fish get water and can be evenly dispersed in it; but it has poor solubility in water, just like oil and water are difficult to blend. This property needs to be taken into account when separating, purifying and preparing related products. The physical properties of 2-ethoxy-3 (5/6) -methylpyrazine, from its properties and aroma to its boiling point, density and solubility, are unique and interrelated, and play a key guiding role in its application in the fields of fragrance and chemical industry.
    Is 2-Ethoxy-3 (5/6) -methyl pyrazine chemically stable?
    The chemical properties of 2-ethoxy-3 (5/6) -methylpyrazine are still stable. In its molecular structure, the pyrazine ring has a certain conjugate system, which endows it with a relatively stable chemical skeleton. The presence of ethoxy groups can produce electronic effects with surrounding groups due to the lone pair electrons of oxygen atoms, but this effect has a slight impact on molecular stability. Although the introduction of methyl groups has changed the electron cloud distribution of the molecule, it has not caused a significant active check point in the molecular structure.
    From the perspective of reactivity, the nitrogen atom on the pyrazine ring is slightly basic and may protonate under acidic conditions. However, the pyrazine ring itself is conjugated and stable, and it is difficult to open or rearrange the ring under normal conditions. And ethoxy is relatively inert to methyl, and it is not easy to replace and eliminate when there are no special reagents and conditions.
    However, it should be noted that in case of strong oxidants, strong acids or strong bases, and extreme conditions such as high temperature and high pressure, its stability may be affected. Strong oxidants such as potassium permanganate may cause oxidation of ethoxy and methyl; strong acids and strong bases may promote nucleophilic substitution and electrophilic substitution on the pyrazine ring, thereby changing the molecular structure.
    In conclusion, under normal and conventional conditions, 2-ethoxy-3 (5/6) -methylpyrazine is chemically stable, but under specific extreme conditions or special reagents, or a chemical reaction occurs to change its chemical properties.
    What are the methods for preparing 2-Ethoxy-3 (5/6) -methyl pyrazine?
    2-Ethoxy-3 (5/6) -methylpyrazine. There are many different methods for preparing this substance, and the details are as follows.
    First, the corresponding pyrazine derivative can be started. With a specific pyrazine compound, under suitable reaction conditions, ethoxy and methyl are introduced. If a pyrazine substrate is selected, under the catalytic action of a base, with an ethoxy-containing reagent, such as halogenated ethane, the nucleophilic substitution reaction is carried out to introduce ethoxy. Then, with an appropriate methylating reagent, such as iodomethane, under specific conditions, the methyl group is connected to the corresponding position of the pyrazine ring, and the target product can be obtained through a multi-step reaction.
    Second, we can consider starting from the construction of pyrazine rings. Select suitable nitrogenous and carbon-containing raw materials, such as diamines and dicarbonyl compounds. Under the presence of suitable temperatures, solvents and catalysts, the two undergo cyclization and condensation reactions to initially form pyrazine rings. Then, the obtained pyrazine products are functionalized according to the above method of introducing ethoxy and methyl groups, and the reaction conditions are carefully adjusted to make each step of the reaction proceed smoothly, so as to achieve the purpose of preparing 2-ethoxy-3 (5/6) -methylpyrazine. When preparing
    , it is necessary to pay attention to the precise control of the reaction conditions, such as temperature, pH, reaction time, etc., which have a great impact on the reaction process and product purity. The choice of solvent is also critical. According to the characteristics of each step of the reaction, the appropriate solvent should be selected to facilitate the efficient progress of the reaction. And after each step of the reaction, the product should be properly separated and purified to ensure the quality and purity of the final product.
    What is the price range for 2-Ethoxy-3 (5/6) -methyl pyrazine in the market?
    My question is about the market price range of 2-ethoxy-3 (5/6) -methylpyrazine. However, the price on the market often changes due to many factors, such as differences in origin, quality differences, supply and demand conditions, seasonal changes, and the volume of transactions.
    If this chemical is traded in a place where chemical raw materials are of high quality and in large quantities, its price may be relatively low. The origin is close to the user, and it can also reduce the cost of transportation, so the price will drop. If the market demand exceeds the supply, the price will rise; otherwise, if the supply exceeds the demand, the price may fall.
    As far as I know, the current market price range ranges from tens to hundreds of yuan per kilogram. However, this is only an approximate figure and is not an exact value. To get an accurate price, you need to consult the chemical raw material supplier in detail, or check the real-time quotation of the chemical product trading platform to know the exact price range.