2 Amino 5 Cyanopyrazine
pyridine pyrrole pyrazine piperidine piperazine

2-AMINO-5-CYANOPYRAZINE

    Specifications

    HS Code

    140314

    Chemical Formula C5H4N4
    Molecular Weight 120.11 g/mol
    Appearance Solid (usually a powder)
    Color Typically white to off - white
    Odor Odorless (or very faint odor)
    Melting Point Around 220 - 225 °C
    Solubility In Water Slightly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Stability Stable under normal conditions, but can react with strong oxidizing or reducing agents
    Cas Number 5467-77-4

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    General Information
    Where to Buy 2-AMINO-5-CYANOPYRAZINE in China?
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    Frequently Asked Questions

    As a leading 2-AMINO-5-CYANOPYRAZINE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-AMINO-5-CYANOPYRAZINE?
    2-Amino-5-cyanopyrazine, an important organic compound, has its key uses in many fields.
    First, in the field of medicinal chemistry, it is an important synthesis intermediate. In the process of creating many drugs, 2-amino-5-cyanopyrazine plays an indispensable role. Due to its specific chemical structure, it can be constructed through a series of chemical reactions with specific pharmacological activities. Through this synthesis path, it is possible to develop therapeutic drugs for various diseases, such as antibacterial drugs, antiviral drugs, and even anti-cancer drugs.
    Second, in the field of materials science, it also has its uses. The preparation of some functional materials requires the introduction of organic compounds with specific structures as building units. The unique structure of 2-amino-5-cyanopyrazine may endow the material with special electrical, optical or mechanical properties. For example, in the synthesis of some organic optoelectronic materials, it may participate in the formation of a specific conjugate system, thereby improving the photoelectric conversion efficiency of the material, which can be used in organic Light Emitting Diode (OLED), solar cells and other devices.
    Furthermore, in the field of pesticides, it also has potential applications. It can be used as a key raw material for the synthesis of new pesticides, and can develop high-efficiency, low-toxicity and environmentally friendly pesticide products. With its structural characteristics, it may interact with specific biological targets in pests to achieve precise insecticidal or bactericidal effects, while reducing adverse effects on the environment and non-target organisms.
    In short, 2-amino-5-cyanopyrazine has shown broad application prospects in many fields such as medicine, materials, and pesticides due to its unique chemical structure, providing an important material basis for technological innovation and development in related fields.
    What are the physical properties of 2-AMINO-5-CYANOPYRAZINE?
    2-Amino-5-cyanopyrazine is an important organic compound. Its physical properties are particularly critical and are relevant to many fields of application.
    Looking at its properties, under normal temperature and pressure, it is mostly white to light yellow crystalline powder. This form is easy to store and use, and the shape of the powder also affects its dispersion and reaction characteristics in different media.
    When it comes to melting point, it is about 162-166 ° C. The value of the melting point can help to identify the purity of the substance. The melting point of the pure product is relatively fixed. If it contains impurities, the melting point is often deviated. This property is crucial in the process of quality control and purification. < Br >
    In terms of solubility, it has low solubility in water, but it can be soluble in some organic solvents, such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF), etc. Such solubility characteristics provide a basis for the selection of solvents in organic synthesis reactions. In a specific reaction system, selecting a suitable solvent can ensure that 2-amino-5-cyanopyrazine is fully dissolved, thereby promoting the smooth progress of the reaction.
    Furthermore, the stability of this substance cannot be ignored. Under conventional environmental conditions, 2-amino-5-cyanopyrazine has certain chemical stability. However, when exposed to specific chemical reagents such as strong oxidants, strong acids, and strong bases, chemical reactions are prone to occur, resulting in structural changes. Therefore, during storage and use, it is necessary to avoid contact with such substances to ensure the integrity of their chemical structure and stable properties.
    In summary, the physical properties of 2-amino-5-cyanopyrazine, from their properties, melting point, solubility to stability, have a profound impact on their application in scientific research, industrial production and other fields. In-depth understanding and rational utilization of these properties is the key to maximizing their value.
    What are the chemical properties of 2-AMINO-5-CYANOPYRAZINE?
    2-Amino-5-cyanopyrazine, this is an organic compound. It has a variety of chemical properties, let me tell you one by one.
    First of all, its physical properties, or solid under normal conditions, vary depending on specific environmental conditions. Its color may be white to light yellow powder, which is determined by its chemical structure and crystal morphology.
    As for chemical properties, both amino and cyano groups are active. Amino-NH2O, alkaline, can react with acids to form corresponding salts. In the case of strong acids, such as hydrochloric acid, the amino nitrogen atom can accept protons and form cations. This is a common reaction of acid-base neutralization. It is often used in organic synthesis to change the solubility and reactivity of compounds.
    Cyano-CN is also not inferior, and it has electrophilic and nucleophilic properties. During nucleophilic reactions, cyano-carbon atoms can act as nucleophilic centers and undergo addition or substitution reactions with electrophilic reagents. Under certain conditions, cyano groups can be hydrolyzed and converted into carboxyl-COOH, which is very important in the preparation of carboxyl-containing compounds in organic synthesis.
    Furthermore, the pyrazine ring of 2-amino-5-cyanopyrazine has a conjugated system, which makes the molecule stable to a certain extent. However, due to conjugation, the electron cloud density distribution on the ring is affected by the amino and cyano groups, resulting in different reactivity at different positions on the ring. This compound has a wide range of uses in the field of organic synthesis and can be used as an intermediate to construct complex organic molecular structures through various reactions, laying the foundation for the synthesis of drugs, materials and other substances.
    What are 2-AMINO-5-CYANOPYRAZINE synthesis methods?
    There are various methods for the synthesis of 2-amino-5-cyanopyrazine in the past. One usually starts with pyrazine derivatives and reacts with specific reagents under suitable conditions. For example, choose a pyrazine containing a specific substituent and introduce a halogen atom through the halogenation step. This halogen has good activity and can undergo nucleophilic substitution reaction with reagents containing amino and cyanyl groups.
    At that time, the halogenation step requires temperature control, time control and selection of suitable halogenating agents, such as commonly used hydrogen halide or phosphorus halide. In the nucleophilic substitution step, the ratio of reagents and the choice of reaction solvent are also critical. Common solvents include polar aprotic solvents, which can help reagents dissolve and promote the reaction. < Br >
    There are also nitrogen-containing heterocyclic compounds as raw materials, which are synthesized by cyclization reaction. First, a chain-like precursor containing suitable functional groups is prepared, and then under the action of a catalyst, intramolecular cyclization occurs to construct a pyrazine ring. During this cyclization process, the type, dosage of catalyst and the pH of the reaction environment all affect the formation of the product. If the catalyst activity is not suitable, or the cyclization is incomplete, the yield decreases.
    Another attempt has been made to explore biosynthesis, using the catalytic activity of specific microorganisms or enzymes to synthesize under mild conditions. However, at that time, this biological method has not been widely used due to strict requirements on reaction conditions, and the difficulty of microbial culture and enzyme purification. The process of
    synthesis requires fine control of each step, from the purity of raw materials to the precise regulation of reaction conditions, all of which are related to the quality and yield of the product. Although various synthesis methods at that time had their own advantages and disadvantages, they all laid the foundation for future in-depth research on the synthesis of this compound.
    What is the price range of 2-AMINO-5-CYANOPYRAZINE in the market?
    The price of 2 - AMINO - 5 - CYANOPYRAZINE in the city of Wuguanfu often changes for various reasons. The abundance of raw materials, the difficulty of making methods, and the amount of demand are all causes of price changes.
    In the past, if raw materials were abundant, easy to obtain, and well made, and the market was stable, the price might be in a suitable area. However, if raw materials are scarce, difficult to find, complicated to make, and the market demand surges, the price will rise.
    Nowadays, as far as I know, the price varies from time to time. In the peak season of raw material production, if there is no major change, the price may be relatively flat, and the price per unit may be between [X1] and [X2]. However, if the raw materials are not harvested, or the manufacturing process is in trouble, the price may jump to more than [X3].
    It is also key to seek the market. If many companies compete to buy them for newly developed drugs or newly produced materials, the price will also rise. On the contrary, if there is a shortage of demand and oversupply, the price will decline.
    In short, the price of 2 - AMINO - 5 - CYANOPYRAZINE on the market fluctuates between [X1] and [X3], but this is only an approximation. The actual price often varies with market conditions, which is difficult to determine.