2-Amino-5-chloropyrazine

2-Amino-5-chloropyrazine has a wide range of uses. In the field of medicine, it is a key intermediate for the synthesis of many drugs. Due to its unique chemical structure, it can interact with specific targets in organisms to help develop new antibacterial, antiviral and anti-tumor drugs. For example, in the creation of antibacterial drugs, it can participate in the construction of compounds with unique antibacterial mechanisms, showing good inhibitory activity against drug-resistant bacteria.
It is also an important synthetic raw material in pesticides. It can derive efficient and low-toxic insecticides, fungicides, etc. Due to the structural properties of 2-amino-5-chloropyrazine, these pesticides can precisely act on specific physiological processes of pests or bacteria, achieving good control effects, and have little impact on the environment.
In the field of materials science, it also has applications. It can be used to prepare functional materials, such as some materials with special photoelectric properties. Because its structure can endow materials with unique electronic properties, it may have potential application value in the fields of organic Light Emitting Diodes, sensors and other fields, providing new ways for material performance improvement and functional expansion.
In conclusion, 2-amino-5-chloropyrazine plays an important role in the fields of medicine, pesticides and materials science due to its special structure, and has a driving effect on the development of related industries.

2-Amino-5-chloropyrazine is one of the organic compounds. Its physical properties, first appearance, at room temperature, are mostly white to light yellow crystalline powders, with fine texture and quite pure appearance.
As for the melting point, it is about 155-159 ° C. This melting point characteristic is crucial for the identification and purity judgment of the substance. When the temperature gradually rises, the substance slowly melts from solid to liquid, and this transformation process occurs in an orderly manner according to its specific melting point.
In terms of solubility, 2-amino-5-chloropyrazine is slightly soluble in water. Water is the source of all things, but the dissolution of this substance in water is limited, and only a small number of molecules can be evenly dispersed in it. However, it exhibits good solubility in organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF). In DMSO, it can be rapidly dispersed to form a uniform solution, just like fish entering the ocean, intermolecular interactions and integration.
In addition, its density is also one of the important physical properties. Although the exact value varies slightly due to measurement conditions, it is roughly within a certain range. This density characteristic is related to its existence state in different environments and its distribution when mixed with other substances.
Furthermore, its smell is weak, and it can only detect a faint special smell, without a strong pungent feeling, which is also the embodiment of its physical properties. Various physical properties are related to each other, and together outline the unique physical appearance of 2-amino-5-chloropyrazine, which is of important guiding value in the application research of many fields such as chemical industry and medicine.

The chemical synthesis methods of 2-amino-5-chloropyrazine have been used in ancient times, and there are many kinds. Today, I will describe them in detail.
First, 5-chloropyrazine-2-carboxylic acid is used as the starting material and can be obtained by acylation, aminolysis, dehydration and other multi-step reactions. First, 5-chloropyrazine-2-carboxylic acid is reacted with suitable acylating reagents to obtain the corresponding acid chloride. This step requires attention to the control of reaction conditions. The temperature and reagent ratio are all exquisite. The activity of acid chloride is quite high. When preparing, it should be operated at low temperature to avoid side reactions. Then ammoniolysis with ammonia gas or ammonia derivatives is carried out to generate 5-chloropyrazine-2-formamide. This process requires the selection of an appropriate reaction solvent to facilitate the smooth progress of the reaction. Finally, a molecule of water is removed by the action of a dehydrating agent, and 2-amino-5-chloropyrazine is obtained.
Second, 2,5-dichloropyrazine is used as the starting material. 2,5-dichloropyrazine reacts with ammonia sources under suitable conditions, and ammonia can replace one of the chlorine atoms. However, the selectivity of the reaction needs to be carefully regulated. Reaction temperature, pressure and ammonia concentration all have a great impact on the proportion of the product. The selectivity of the reaction can be improved by adding specific catalysts, such as some metal complexes, to promote the reaction to form 2-amino-5-chloropyrazine. Control the reaction process to avoid excessive aminolysis to form 2,5-diaminopyrazine and other by-products.
Third, nitrogen-containing heterocyclic compounds are also used as raw materials and prepared by cyclization, substitution and other reactions. First construct the pyrazine ring structure, and cyclize the nitrogen-containing raw materials to form the pyrazine parent nucleus through a suitable reaction. The reaction mechanism of this step is complicated, and the structure of the reactants and reaction conditions need to be precisely grasped. 2-Amino-5-chloropyrazine is obtained by introducing chlorine atoms through halogenation reaction, and then substituting amino groups for halogen atoms at specific positions. This method has many steps, and each step requires fine operation to ensure the purity and yield of the final product.
The above synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to comprehensively consider many factors such as the availability of raw materials, the ease of control of reaction conditions, the purity of the product and the cost, and choose the optimal method.

In today's world, the price range of 2 - Amino - 5 - chloropyrazine in the city is difficult to say in a word. Its price often changes for many reasons, such as the abundance of raw materials, the difficulty of process, the amount of demand, the distance of the region, and the competitive situation of the market.
Looking at the price of chemical industry in the past, if the supply of raw materials is sufficient and the production process is simple and mature, the price may be stable and low. On the contrary, if raw materials are scarce, difficult to obtain, or the process is complicated, and a lot of manpower and material resources are required, the price will rise.
Furthermore, the impact of market demand cannot be underestimated. If the demand for this product increases sharply in a certain domain at a certain time, the supply exceeds the demand, and the merchant may raise the price; if the demand is low, the supply exceeds the demand, and the price will also drop for promotional sales.
As for the difference between regions, it is also the key. In places with convenient transportation and industrial agglomeration, the price may be lower than elsewhere due to low transportation costs and good industrial coordination. In remote places, due to the superposition of transportation, storage and other costs, the price may be higher.
The state of market competition also affects the price. If there are many merchants and the competition is intense, in order to compete for customers, the price may be reduced; if the market is almost monopolized, the price may be controlled by a few merchants, and the situation is higher.
However, although it is difficult to determine its price range, it is common sense that when the supply of raw materials is stable, the market competition is orderly, and the demand does not fluctuate greatly, the price per kilogram may be between a few hundred and a few thousand yuan. This is only speculation, and the actual price still needs to be determined according to the current market conditions.

2-Amino-5-chloropyrazine is an important chemical substance. Its storage conditions are related to its quality and stability, and cannot be ignored.
This substance should be stored in a cool and dry place. A cool environment can slow down its chemical reaction due to excessive temperature. If stored in a hot place, the molecular movement will intensify, or its structure will mutate, damaging its inherent chemical properties. As for drying, because moisture is often the medium of chemical reactions, it can cause adverse reactions such as hydrolysis, eroding the purity of 2-amino-5-chloropyrazine.
Furthermore, it should be placed in a well-ventilated place. With good ventilation, harmful gases that may accumulate around can be removed to prevent them from interacting with 2-amino-5-chloropyrazine. And with good ventilation, it can maintain the stability of the storage environment and prevent local temperature and humidity imbalance.
Also keep away from fire sources and oxidants. 2-amino-5-chloropyrazine is in danger of fire, or even explosion. The oxidant has strong oxidizing properties. When it encounters 2-amino-5-chloropyrazine, it is prone to violent oxidation reactions, destroying its chemical structure, and causing safety risks.
It should be sealed and stored. The seal can be separated from outside air, moisture and impurities to maintain its purity and chemical properties. If the seal is not good, air and moisture will drive in for a long time, and it will change over time.
And the place of storage should be clearly marked. The name of "2-Amino-5-chloropyrazine" and its characteristics, storage attention, so that the person who takes it can see it at a glance, avoid operation errors, and ensure the safety of storage and use.