2 Amino 3 Hydroxypyrazine
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-3-hydroxypyrazine

    Specifications

    HS Code

    240348

    Chemical Formula C4H5N3O
    Molar Mass 111.10 g/mol
    Appearance Solid (usually white to off - white)
    Solubility In Water Moderate solubility
    Melting Point 230 - 235 °C (approximate, may vary with purity)
    Boiling Point Decomposes before boiling
    Odor Odorless or very faint odor
    Pka Value Data specific to its acidic or basic groups can be used to calculate relevant pKa values in different environments
    Stability Stable under normal conditions, but may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-Amino-3-hydroxypyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Amino-3-hydroxypyrazine?
    2-Amino-3-hydroxypyrazine has a wide range of uses and is used in various fields.
    First, in the field of pharmaceutical chemistry, this is an important organic synthesis intermediate. During the development of medicine, a series of chemical reactions can be carried out to construct molecular structures with specific biological activities based on 2-amino-3-hydroxypyrazine. For example, the synthesis of some antibacterial drugs, with its unique chemical structure, can combine with specific targets in the body of bacteria, interfere with the metabolic process of bacteria, and achieve antibacterial effect. Or in the research and development of anti-tumor drugs, using it as the starting material and modifying it to create drugs that can precisely act on tumor cells and inhibit the proliferation and diffusion of tumor cells.
    Second, in the field of materials science, it also has extraordinary functions. It can participate in the preparation of special materials, and after appropriate reactions and treatments, it can become a part of the material structure, giving the material special properties. For example, in the synthesis of some photoelectric materials, the introduction of 2-amino-3-hydroxypyrazine can improve the electronic transmission performance of the material, thereby enhancing the performance of the material in optoelectronic devices such as Light Emitting Diode, solar cells and other applications.
    Furthermore, in the field of analytical chemistry, due to its specific chemical properties, it can be used as an analytical reagent. In the qualitative or quantitative analysis of some substances, it is used to react specifically with the target substance to generate products with specific properties, so as to realize the detection and analysis of the target substance. For example, in the detection of some metal ions, 2-amino-3-hydroxypyrazine can form stable complexes with specific metal ions, and the content of metal ions can be accurately determined by detecting the relevant properties of the complexes. From this perspective, although 2-amino-3-hydroxypyrazine is an organic compound, it plays a key role in many fields of modern science and technology, and its wide range of uses cannot be underestimated.
    What are the physical properties of 2-Amino-3-hydroxypyrazine?
    The physical properties of 2-amino-3-hydroxypyrazine are particularly important and relate to many uses. At room temperature, this compound is mostly in the shape of a solid state, and its appearance is often white to light yellow powder. The texture is fine and visible. Its melting point is fixed, about 190-195 ° C. This property can be an important basis for separation, purification and identification.
    When it comes to solubility, 2-amino-3-hydroxypyrazine is slightly soluble in water, although not very soluble, but in hot water, the amount of solubility can increase. In addition, it also has a certain solubility in polar organic solvents such as methanol, ethanol, dimethyl sulfoxide, etc. This characteristic makes it possible to choose a variety of solvents when preparing solutions or participating in chemical reactions.
    Furthermore, the density of 2-amino-3-hydroxypyrazine is also one end of its physical properties. Its density is about 1.53 g/cm ³, although this value may vary slightly due to measurement conditions, it is roughly within this range. This density data is relevant to the measurement and ratio of materials in the process of chemical production and preparation, and should not be underestimated.
    As for its stability, under normal conditions, 2-amino-3-hydroxypyrazine is quite stable. However, if exposed to strong light, high temperature or high humidity, its chemical structure may have a gradual change, which will affect its physical properties and chemical activity. Therefore, when storing, it should be placed in a cool, dry and dark place to ensure its quality.
    What is the chemistry of 2-Amino-3-hydroxypyrazine?
    2-Amino-3-hydroxypyrazine, this is an organic compound. Looking at its chemical properties, it is quite unique.
    It contains amino groups and hydroxyl groups, both of which have active chemical activity. Amino groups can participate in many reactions, such as reacting with acids to form salts, which are like the intersection of a gentleman and a friend. When encountering an acid, the nitrogen atom in the amino group combines with the proton in the acid by virtue of its lone pair of electrons to form a salt. This process is like a friendly embrace between the two, achieving a new harmonious state.
    Hydroxyl groups are also not idle and can participate in esterification reactions. Like a well-prepared event, the hydroxyl group interacts with the acid under specific conditions to remove a molecule of water and form an ester compound. This reaction requires suitable temperature, catalyst and other conditions, just as the event requires the right place and organization.
    In addition, the pyrazine ring structure of 2-amino-3-hydroxypyrazine gives it a certain stability. The pyrazine ring is like a strong castle, providing a stable structure for the entire molecule. However, the substituents on its ring add another activity to the molecule.
    In different chemical reaction environments, the amino and hydroxyl groups of 2-amino-3-hydroxypyrazine either act alone or cooperate to initiate a variety of chemical reactions. In this way, the compound is like a shining star in the field of organic synthesis and has a wide range of application potential. It can be used as a key intermediate to help synthesize various complex and special functional organic compounds.
    What are 2-Amino-3-hydroxypyrazine synthesis methods?
    The synthesis method of 2-amino-3-hydroxypyrazine has been explored by many parties throughout the ages, and the following is described in detail.
    First, a specific pyrazine derivative is used as the starting material. Take this derivative first and place it in a delicately prepared reaction system, in which an appropriate amount of catalyst needs to be added. This catalyst, like a guide for chemical reactions, can significantly increase the reaction rate and guide the reaction in the desired direction. Then, under precisely controlled temperature and pressure conditions, slowly react. The regulation of temperature is like controlling the temperature, not overheating or low temperature, otherwise it will affect the formation of the product. The grasp of pressure is also crucial, and it needs to complement the temperature. In this way, after several hours or even days of reaction, the raw material is gradually converted to produce the target product 2-amino-3-hydroxypyrazine.
    Second, another path is adopted. Nitrogen-containing heterocyclic compounds are used as the starting cornerstone and combined with reagents with specific functional groups. This bonding process needs to be carried out in a suitable solvent. The choice of solvent is very particular, and it needs to be able to dissolve the reactants well without interfering with the reactants. Then, specific reaction aids are added, which can optimize the reaction environment and promote the efficient progress of the reaction. Under certain reaction time and conditions, the molecular structure of 2-amino-3-hydroxypyrazine is finally constructed through ingenious transformation and recombination between functional groups.
    Third, more basic chemical raw materials, such as simple small molecule compounds containing carbon, nitrogen and oxygen, are also achieved through multi-step reactions. The first step is to make these small molecule compounds undergo a specific condensation reaction to build a preliminary molecular framework. This step requires quite strict reaction conditions, and requires precise control of the ratio of reactants, the pH of the reaction and other factors. Subsequently, after several steps of modification and transformation, amino and hydroxyl functional groups were gradually introduced, carefully carved, and finally the complete molecule of 2-amino-3-hydroxypyrazine was formed to obtain this precious organic compound.
    2-Amino-3-hydroxypyrazine in what areas
    2-Amino-3-hydroxypyrazine is useful in various fields. In the field of medicine, this is an important synthetic building block. It can be used to create various drugs to treat various diseases. Because of its unique structure, it can interact with many biological targets in the body, or can regulate physiological functions, or can cure diseases. For example, when developing antibacterial drugs, it may use its own structural characteristics to interfere with the metabolic pathway of bacteria, thereby inhibiting the growth and reproduction of bacteria.
    In the field of materials science, 2-amino-3-hydroxypyrazine also has its function. Can participate in the preparation of special functional materials. Using it as a raw material, through specific chemical reactions, materials with special optical and electrical properties can be synthesized. Such materials may be applied to optoelectronic devices, such as Light Emitting Diode, solar cells, etc., to contribute to improving the performance of devices.
    In the field of agriculture, it can also be seen. Or can be used to develop new pesticides or plant growth regulators. With its chemical properties, it may affect the physiological processes of plants, promote plant growth and development, enhance plant resistance, resist pest attacks, and ensure crop yield and quality.
    In chemical research, 2-amino-3-hydroxypyrazine is often used as a key intermediate. Chemists can chemically modify it to generate a wide range of compounds with different structures, thus expanding the variety of chemical substances, contributing to the development of organic synthetic chemistry, and helping to explore more novel chemical reactions and properties.