2 Amino 3 5 Dibromopyrazine
pyridine pyrrole pyrazine piperidine piperazine

2-Amino-3,5-dibromopyrazine

    Specifications

    HS Code

    149879

    Chemical Formula C4H2Br2N4
    Molecular Weight 265.909 g/mol
    Appearance Solid (likely white to off - white powder)
    Melting Point Data may vary, check literature
    Boiling Point Data may vary, check literature
    Solubility In Water Low solubility (amine and pyrazine rings may offer some polarity but bromine substituents reduce it)
    Solubility In Organic Solvents Soluble in polar organic solvents like DMSO, DMF
    Pka Amine Group Data may vary, around 4 - 6 for the amino group in pyrazine derivatives
    Density Data may vary, check literature
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    General Information
    Where to Buy 2-Amino-3,5-dibromopyrazine in China?
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    Frequently Asked Questions

    As a leading 2-Amino-3,5-dibromopyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2-Amino-3,5-dibromopyrazine?
    2-Amino-3,5-dibromopyrazine is a class of organic compounds. Its main uses are quite extensive, and it has a significant effect in the field of medicinal chemistry.
    One of them can be a key intermediate for drug synthesis. When creating new antibacterial and antiviral drugs, 2-amino-3,5-dibromopyrazine is often used as the starting material. Due to its unique molecular structure, various active groups can be introduced through many chemical reactions, and then drug molecules with specific pharmacological activities can be constructed. For example, by substitution reactions with compounds containing specific functional groups, drugs with targeted inhibitory effects on specific pathogens can be generated, adding a weapon to human disease fighting.
    Second, it is also useful in the field of materials science. It can be used as a raw material for the preparation of special functional materials. After specific processing, it can participate in the construction of materials with unique electrical and optical properties. For example, in the preparation of organic optoelectronic materials, 2-amino-3,5-dibromopyrazine can impart better charge transfer properties or fluorescence properties to the material, and may have potential application value in the manufacturing of organic Light Emitting Diode (OLED) devices, opening up new paths for the development of materials science.
    Furthermore, in the field of pesticide chemistry, it also shows certain potential. It can be used to develop new pesticides, target specific pests or plant diseases, and play a high-efficiency control effect. Relying on the relationship between its structure and biological activity, through rational design and modification, it is expected to create environmentally friendly, high-efficiency and low-toxicity pesticide varieties, which will help the sustainable development of agriculture and protect the healthy growth of crops.
    From this perspective, although 2-amino-3,5-dibromopyrazine is an organic compound, it has important uses in many fields such as medicine, materials, and pesticides, and has contributed to the development of related disciplines and industries.
    What are the physical properties of 2-Amino-3,5-dibromopyrazine?
    2-Amino-3,5-dibromopyrazine, which has special physical properties and is related to chemical affairs, is quite important. Its color state, at room temperature, is often white-like powder, with fine texture and uniform appearance. This is the visually recognizable state.
    When it comes to the melting point, its melting point is quite high, about 250 to 255 degrees Celsius. When heated up to this point, it begins to melt into a liquid state, which is due to the characteristics of its intermolecular forces. The determination of the boiling point also requires specific equipment and rigorous operation. Because of its stable chemical structure, the attractive force between molecules is large, and high energy is required to make it gasify.
    As for solubility, in the solvent of water, the degree of solubility is very small, and it seems to be incompatible with water. Because the polarity of the compound is contrary to the polarity of water, it is difficult to blend. However, in organic solvents, such as dichloromethane, N, N-dimethylformamide, its solubility is quite good, and it can be miscible with these solvents to form a uniform solution. This property can facilitate the separation, purification and choice of reaction medium in the process of organic synthesis.
    The density of 2-amino-3,5-dibromopyrazine is higher than that of ordinary water. When placed in water, it can be seen that it sinks to the bottom, which is due to its large molecular mass and compact structure. Its stability is quite high under general conditions. However, in special chemical environments such as strong acids, strong bases or high temperatures, strong oxidants, etc., the structure may be damaged, triggering chemical reactions and generating different compounds. These are all important physical properties of 2-amino-3,5-dibromopyrazine, which are of key significance in the research and application of chemistry.
    What is the chemical synthesis method of 2-Amino-3,5-dibromopyrazine?
    The chemical synthesis of 2-amino-3,5-dibromopyrazine has been known for a long time and has been tempered by practice. The following are the common methods for its synthesis, described in ancient Chinese.
    First, choose a suitable starting material, and pyrazine is often used as the base material. To obtain this 2-amino-3,5-dibromopyrazine, first modify the pyrazine. In a suitable reaction vessel, put pyrazine and dissolve it in a suitable solvent. This solvent needs to be able to fully disperse and stabilize the reactants, such as common organic solvents, halogenated hydrocarbons and the like.
    Then bromine atoms are introduced. The method of bromination is often added with brominating reagents. Commonly used brominating reagents, such as liquid bromine, are compatible with suitable catalysts. This catalyst can help bromine atoms to be precisely added to the specific positions of the pyrazine ring, that is, the 3rd and 5th positions. During the reaction, the temperature should be controlled and the time should be controlled. If the temperature is too high, it may cause excessive bromination or side reactions; if the temperature is too low, the reaction will be slow and the efficiency will be low. Generally speaking, between low temperature and moderate temperature, the reaction should be slowly observed, and the reaction process should be closely observed.
    After the bromination reaction is completed, the body after 3,5-dibromo pyrazine is obtained. At this time, the amination step is carried out again. The method of amination is mostly based on reagents containing amino groups. If a derivative of ammonia is used, react with 3,5-dibromopyrazine under specific conditions. This reaction condition also needs to be carefully regulated, such as the pH of the reaction system, temperature and reaction time. The appropriate pH can promote the effective substitution of amino groups, and the temperature and time depend on the completeness of the reaction.
    After the reaction is completed, the product is separated and purified to obtain pure 2-amino-3,5-dibromopyrazine. The separation method is often used in combination with extraction, distillation, recrystallization, etc. Extraction can initially separate the product from the impurities, distillation can further purify according to the difference in boiling point, and recrystallization can obtain high-purity crystal products.
    So, according to the above steps, 2-amino-3,5-dibromopyrazine can be synthesized, but the way of synthesis requires attention to the subtleties in order to obtain the ideal product.
    What is the price range of 2-Amino-3,5-dibromopyrazine in the market?
    At present, the price of chemistry often changes due to various reasons, such as the abundance of materials, the difficulty of craftsmanship, and the amount of market demand. 2 - Amino - 3,5 - dibromopyrazine This chemical reagent is difficult to determine the price in the market.
    In the past, the price of chemical substances was constant. If the preparation of this material requires rare materials, or the process is complicated, time-consuming and costly, the price will be high. On the contrary, if the raw materials are easy to obtain, the production method is simple, and the price may be slightly cheaper.
    However, the market is changing rapidly today. If you want to know the exact price range of 2 - Amino - 3,5 - dibromopyrazine, you should consult the chemical reagent merchants or the relevant chemical trading platforms. There are many merchants there, and the quotations are different. If you compare them comprehensively, you can get a more accurate price range at the moment. Or because of the amount of purchase, the price is also different, and the quantity is large or you can get a preferential price. Therefore, if you want to know the details, it is the right way to visit the market and consult the merchants in person.
    What are the Quality Standards for 2-Amino-3,5-dibromopyrazine
    2-Amino-3,5-dibromopyrazine is an important chemical substance in organic synthesis. Quality Standards for it are related to many key aspects.
    First of all, the appearance is discussed. It should be in the form of a white-like to light yellow crystalline powder. It has a uniform color and no obvious impurities and foreign matter. This is one of the basic thresholds to ensure its quality.
    In terms of purity, this is the top priority. Generally speaking, its purity needs to reach more than 98.0%, which can be determined by precise analytical methods such as high-performance liquid chromatography (HPLC). High purity can ensure stable performance in subsequent synthesis reactions. If the purity is insufficient, impurities may interfere with the reaction process, resulting in a decrease in the yield of the product or even the formation of wrong products.
    Melting point is also a key quality indicator. The melting point of 2-amino-3,5-dibromopyrazine is roughly within a specific range, such as [specific melting point range], and the melting point can be accurately determined by a melting point meter. The accuracy of the melting point can reflect the purity of the substance and the integrity of the crystal structure. If the melting point deviation is too large, it is very likely to indicate that the substance is impure or the crystal form is abnormal.
    The relevant moisture content must generally be controlled below 0.5%. Excessive moisture may affect its chemical stability, and even act as a interfering factor in some reactions, changing the reaction path. The Karl Fischer method is often used to determine moisture, which is highly sensitive and can accurately determine trace moisture.
    As for the content of heavy metals, it must be strictly controlled. Take lead (Pb) as an example, its content should not exceed 10ppm. Heavy metal impurities will not only affect the performance of the product, but also pose serious safety hazards in subsequent applications, especially in the synthesis of pharmaceuticals and food-related fields. Advanced technologies such as atomic absorption spectroscopy (AAS) or inductively coupled plasma mass spectrometry (ICP-MS) are often used to detect heavy metals.
    The above Quality Standards are the key elements to ensure the quality of 2-amino-3,5-dibromopyrazine, and are of vital significance in many aspects such as production and scientific research.