2 5 Dibromo 3 Methoxypyrazine
pyridine pyrrole pyrazine piperidine piperazine

2,5-dibromo-3-methoxypyrazine

    Specifications

    HS Code

    727871

    Chemical Formula C5H4Br2N2O
    Molecular Weight 265.906

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    General Information
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    Frequently Asked Questions

    As a leading 2,5-dibromo-3-methoxypyrazine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2,5-dibromo-3-methoxypyrazine?
    2% 2C5-dibromo-3-methoxyacetophenone, its chemical properties are as follows:
    In this compound, the bromine atom coexists with the methoxy group and acetophenone structure. The bromine atom has the characteristics of a halogen atom and can participate in nucleophilic substitution reactions. Under the action of appropriate nucleophilic reagents, the bromine atom can be substituted, such as reacting with nucleophilic reagents such as alkoxides and amines to form new substitution products.
    Methoxy group is the power supply group, which can increase the electron cloud density of the benzene ring and affect the reactivity of the benzene ring. This power supply effect makes the ortho and para-sites of the benzene ring more prone to electrophilic substitution reactions, such as halogenation, Due to the action of methoxy groups, the reaction tends to proceed in its adjacent and para-positions. In the
    acetophenone structure, the carbonyl group is an electron-withdrawing group, which can reduce the electron cloud density of the benzene ring, and then this effect interacts with the methoxy group. Carbonyl groups can also participate in many reactions, such as addition reactions with nucleophiles, like reactions with Grignard reagents, which can generate corresponding alcohols. In addition, the α-hydrogen of carbonyl groups has a certain activity, and halogenation or condensation reactions can occur under the action of bases.
    In conclusion, 2% 2C5-dibromo-3-methoxyacetophenone exhibits diverse chemical properties due to the characteristics and interactions of functional groups, and has important uses in the field of organic synthesis. Various organic compounds can be constructed through different reaction paths.
    What are the common synthesis methods of 2,5-dibromo-3-methoxypyrazine?
    The common synthesis methods of 2% 2C5-dibromo-3-methoxybenzaldehyde are as follows:
    One is to use the corresponding phenol as the starting material. First, the phenol is reacted with the halogenated alkane under basic conditions to achieve methoxylation, and then the bromine atom is introduced at a specific position by halogenation reaction. For example, m-cresol is used as the starting material and reacted with iodomethane in an alkaline environment to generate m-methoxytoluene, and then brominated with a suitable brominating agent, such as liquid bromine or N-bromosuccinimide (NBS), under a specific catalyst or light conditions, the target product can be obtained. The advantage of this path is that the raw materials are common and easy to obtain, and the steps are relatively clear. However, the selectivity of the bromination step may need to be carefully regulated to prevent unnecessary side reactions.
    The second is to use benzaldehyde derivatives as starting materials. The benzaldehyde ring of benzaldehyde is brominated first, and then the methoxy group is introduced. Benzaldehyde can be selected, and bromine is used as the brominating agent. Under the catalysis of appropriate catalysts such as iron powder or iron tribromide, the specific position of the benzene ring is brominated to obtain bromobenzaldehyde-containing intermediates. Then, methoxylation reagents such as sodium methoxide are used, and methoxy groups are introduced under suitable solvents and reaction conditions. The advantage of this method is that the bromination position selectivity may be easier to control, but the bromination reaction conditions may be stricter, and the methoxylation step
    The third can be synthesized by the Grignard reagent method. Halogenated aromatics are used as starting materials to prepare Grignard reagents, which react with methoxy-substituted carbonyl compounds to form alcohol intermediates, and then oxidize to obtain the target product 2% 2C5-dibromo-3-methoxybenzaldehyde. Although this method can construct complex structures, the preparation of Grignard reagents requires an anhydrous and oxygen-free environment, which requires high reaction operation.
    All these methods have advantages and disadvantages. In actual synthesis, the appropriate synthesis path needs to be weighed according to various factors such as raw material availability, cost, purity and yield of the target product.
    In which fields is 2,5-dibromo-3-methoxypyrazine used?
    2% 2C5-dibromo-3-methoxybenzaldehyde, which is used in medicine, pesticides, materials and other fields.
    In the field of medicine, it is an important intermediate in organic synthesis. In the synthesis path of many drugs, this is the starting material or key intermediate. For example, in the preparation of some compounds with specific biological activities, 2% 2C5-dibromo-3-methoxybenzaldehyde can build the core structure of drug molecules through a series of reactions, and then lay the foundation for the development of new antibacterial and anti-tumor drugs.
    In the field of pesticides, with its unique chemical structure, it can participate in the synthesis of a variety of high-efficiency pesticides. It can be used to prepare pesticide components with high activity for specific pests or diseases. By precisely designing reactions, adjusting their chemical properties and activities, the effect of pesticides on target organisms can be improved, and the impact on non-target organisms can be reduced, so as to achieve the creation of green and efficient pesticides.
    In the field of materials, it can be used as a synthetic precursor of functional materials. By polymerizing or modifying with other organic compounds, materials with special optical, electrical or thermal properties can be prepared. For example, in the synthesis of organic photoelectric materials, the introduction of this substance can change the molecular structure and electron cloud distribution of the material, thereby optimizing the photoelectric conversion efficiency of the material. It is used in organic Light Emitting Diodes, solar cells and other devices.
    What is the market price of 2,5-dibromo-3-methoxypyrazine?
    Today there is 2,5-dibromo-3-methoxyacetophenone, what is the market price? This product is in the market, and its price varies depending on quality, quantity, and market conditions. If the quality is high and the quantity is large, the price may be slightly lower; if the quality is low, the price may be slightly higher.
    I have tried various shops in the market, and I may buy this product for the needs of pharmacy and research. In the pharmaceutical workshop, in order to seek good quality, I will not hesitate to buy it at a high price, although the price is high. However, in the ordinary chemical shop, if the quantity is not huge, the price is also moderate, so that it can be used for various research tests.
    The market situation of Guanfu, the price of this product ranges from a few dollars to tens of dollars per gram. It varies depending on the procurement of raw materials and the simplicity of the manufacturing process. If raw materials are easy to obtain, the manufacturing process is straight, and the price will go down; if raw materials are rare and the manufacturing process is complicated, the price will rise.
    And the market is easy to change over time, and the price is also variable. When raw materials are abundant, the price may drop slightly; if raw materials are scarce, merchants must increase the price to protect their profits. In order to know the exact price, when you consult pharmaceutical companies and chemical merchants around the world, you can get a near-real price.
    What are the storage conditions for 2,5-dibromo-3-methoxypyrazine?
    2% 2C5-dibromo-3-methoxyacetophenone, this is a precious organic compound, and its storage conditions are quite critical. According to the principles of "Tiangong Kaiwu", each product has its own characteristics and exists in a way that can preserve its quality and prolong its use.
    When storing this compound, the first environment is dry. Because its properties are easy to contact with water vapor and change, it needs to be placed in a dry place and protected from moisture. As mentioned in "Tiangong Kaiwu", all products should be stored dry to prevent mildew and rot. The same is true for this compound. If it is in a humid environment, the functional groups such as bromophobic groups and methoxy groups are disturbed, causing its structure to mutate and lose its original properties. < Br >
    The second is the appropriate temperature. It should be stored in a cool place to avoid hot topics at high temperatures. Under high temperatures, the molecular movement intensifies, and the stability of this compound may be damaged, or reactions such as decomposition and polymerization may occur. According to "Tiangong Kaiwu", many materials are damaged due to temperature inappropriateness, so the temperature of this compound should be controlled within an appropriate range to ensure the stability of its chemical properties.
    Furthermore, it must be protected from light. Light is often the cause of chemical reactions. This compound may stimulate electron transitions in molecules due to light, causing chemical bonds to break or rearrange. Therefore, when storing, it is advisable to use a light-shielding device, such as a dark glass bottle, to prevent it from contacting with light.
    Also, the storage place should be well ventilated. Even if all kinds of protection are taken, the compound may still have a small amount of volatilization. If the ventilation is not smooth and the volatile gas accumulates, one will damage its quality and the other may cause safety. According to the method created by "Tiangong Kaiwu", ventilation is essential for creating an indoor environment, and the same is true for the storage of compounds.
    In addition, this compound should be stored in isolation from oxidants, acids, bases and other substances. Because of its specific chemical activity, it is easy to cause violent chemical reactions when it encounters the above substances, resulting in danger. If "Tiangong Kaiwu" records the compatibility of various materials, the storage of this compound should also strictly abide by this rule.